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o-Toluidine

o-Toluidine structure

CAS No:
95-53-4
Formula:
C7H9N
Chemical Name:
o-Toluidine
Synonyms:
Benzenamine,2-methyl-;o-Toluidine;2-Methylbenzenamine;2-Aminotoluene;o-Methylaniline;o-Methylbenzenamine;2-Methyl-1-aminobenzene;2-Toluidine;2-Methylaniline;o-Tolylamine;1-Amino-2-methylbenzene;o-Aminotoluene;2-Amino-1-methylbenzene;2-Methylphenylamine;2-Tolylamine;NSC 15348
Categories:
Organic Chemistry > Heterocyclic Ring

Description

o-Toluidine (ortho-toluidine) is an organic compound with the chemical formula C7H9N.o-Toluidine is primarily used in the manufacture of dyes. o-Toluidine is highly toxic to humans when absorbed through the skin, inhaled as vapor, or swallowed. Acute (short-term) exposure of humans to o-toluidine affects the blood (i.e., methemoglobinemia), with clinical signs of central nervous system depression. The chronic (long-term) effects in workers exposed to o-toluidine include anemia, anorexia, weight

O-toluidine (ortho-toluidine) is an organic compound with the chemical formula C7H9N. This arylamine is a colorless to pale-yellow liquid with a poor solubility in water.

o-Toluidine Basic Attributes

Molecular Weight：

107.15

Exact Mass：

107.15

BRN：

741981

EC Number：

202-429-0

HScode：

29214300

Characteristics

PSA：

XLogP3：

1.43

Appearance：

light yellow to light amber liquid

Density：

1.008 g/cm³ @ Temp: 20 °C

Melting Point：

-16.3 °C

Boiling Point：

200.3 °C

Flash Point：

185 °F

Refractive Index：

1.568

Water Solubility：

H2O: 1.5 g/100 mL (25 ºC)

Storage Conditions：

2-8°C

Vapor Pressure：

0.26 mm Hg ( 25 °C)

Vapor Density：

3.7 (vs air)

Toxicity：

Oral-rat LD50: 670 mg/kg; Oral-Mouse LD50: 520 mg/kg

Flammability characteristics：

Open flame is flammable; reacts strongly with nitric acid; burning emits toxic nitrogen oxide fumes

Explosive limit：

1.5-7.5%(V)

Odor：

Aromatic aniline-like odor

Safety Information

Packing level：

Hazard category：

6.1

Transport codes：

UN 2920 8/PG 1

wgk germany：

hazard class code：

45-23/25-36-50-35-20/22-10-39/23/24/25-23/24/25-11

safety instructions：

53-45-61-36/37/39-26-36/37-16-7

RTECS Number：

XU2975000

Marks：

T,N,F

Storage features：

The warehouse is ventilated, low temperature and dry; stored separately from acids and oxidants

Explosive characteristics：

Explosive when mixed with air

Stability/Shelf Life：

Stable under normal temperatures and pressures. Substance undergoes color change upon exposure to light and air.

Precautionary statement(s)：

P201-P261-P273-P301 + P310-P305 + P351 + P338-P311

Hazard Statements：

H301-H319-H331-H350-H400

RIDADR：

UN 1708

Toxicity

Toxicity class：

moderately toxic

o-Toluidine Use and Manufacturing

Methods of Manufacturing

The preparation method is prepared by catalytic hydrogenation reduction of o-nitrotoluene. Due to the different hydrogenation catalysts, the reaction conditions are different. For example, a copper catalyst is used and the reaction temperature is 260°C, and a nickel catalyst can also be used.

Uses

Used in the production of dye products such as date red base GBC, scarlet base G, red base RL, naphthol ASD, acid pink 3B, basic magenta and basic pink T, as well as pesticides insecticidal amidine, saccharin, vulcanization accelerator, Beneficiation agent toluene arsenic acid, etc.

Analysis Methods

Name	Column Shape	Active Phase(℃)	Retention index	Temperature Control	Method	Comments	Reference
Kovats' RI, polar column, isothermal	Packed	PEG-2000	1796.	179.	isothermal	He, Celite 545 (44-60 mesh); Column length: 3. m	Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal	Packed	PEG-2000	1807.	180.	isothermal	He, Celite 545 (44-60 mesh); Column length: 3. m	Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal	Packed	PEG-2000	1808.	200.	isothermal	He, Celite 545 (44-60 mesh); Column length: 3. m	Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal	Packed	PEG-2000	1814.	200.	isothermal	He, Celite 545 (44-60 mesh); Column length: 3. m	Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal	Capillary	DB-1	1032.7		temperature ramp	30. m/0.25 mm/0.25 μm, He, 3. K/min; T_start: 40. C; T_end: 325. C	Sun, G.Stremple, P.Retention index characterization of flavor, fragrance, and many other compounds on DB-1 and DB-XLB2003, retrieved from http://www.chem.agilent.com/cag/cabu/pdf/b-0279.pdf.

Computed Properties

Molecular Weight:107.15
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:107.073499291
Monoisotopic Mass:107.073499291
Topological Polar Surface Area:26
Heavy Atom Count:8
Complexity:70.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Synthesis Route

75794-20-6

100305-95-1

67-66-3

67-66-3

Material

Methanol

Price Analysis

Make your o-Toluidine purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on o-Toluidine prices .

Data: 2026-07-17
Price: 13000.00Yuan/mt
Change: 5200.0

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