N,4-Dimethylbenzylamine
-
N,4-Dimethylbenzylamine
structure -
-
CAS No:
699-04-7
-
Formula:
C9H13N
-
Chemical Name:
N,4-Dimethylbenzylamine
-
Synonyms:
Benzenemethanamine,N,4-dimethyl-;Benzylamine,N,p-dimethyl-;N,4-Dimethylbenzenemethanamine;N,4-Dimethylbenzylamine;N-Methyl-N-(4-methylbenzyl)amine;N-Methyl-4-methylbenzylamine;N-(4-Methylbenzyl)-N-methylamine;4-Methyl-N-methylbenzylamine;1-(4-Methylphenyl)-N-methylmethanamine
-
CAS No:
Safety Information
R22;R34
S23-S26-S36/37/39
C:Corrosive;
P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P405, P501
H302+H312+H332
|Danger|H302+H312+H332 (100%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
N,4-Dimethylbenzylamine Use and Manufacturing
To a stirred solution of 4-methylbenzyl chloride (2.5 g, 17.85 mmol) in EtOH (15 ml) was added 40 percent methylamine solution (5 ml) and stirred for 4 h . It was monitored by thin layer chromatography. The reaction mixture was evaporated, quenched with water (30 ml) and extracted in dichloromethane (2x 25 ml). The combined organic layer was dried over anhydrous sodium sulfate and concentrated under vacuo to afford yellow oil (2.1 g, 87percent).To a stirred solution of 4-methylbenzyl chloride (2.5 g, 17.85 mmol) in EtOH (15 ml) was added 40 percent methylamine solution (5 ml) and stilted for 4 h. It was monitored by thin layer chromatography. The reaction mixture was evaporated, quenched with water (30 ml) and extracted in dichloromethane (2x 25 ml). The combined organic layer was dried over anhydrous sodium sulfate and concentrated under vacuo to afford yellow oil (2.1 g, 87percent).
Computed Properties
Molecular Weight:135.21
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:135.104799419
Monoisotopic Mass:135.104799419
Topological Polar Surface Area:12
Heavy Atom Count:10
Complexity:82.7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
