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Proxibarbal

Proxibarbal structure

Proxibarbal 

structure
  • CAS No:

    2537-29-3

  • Formula:

    C10H14N2O4

  • Chemical Name:

    Proxibarbal

  • Synonyms:

    2,4,6(1H,3H,5H)-Pyrimidinetrione,5-(2-hydroxypropyl)-5-(2-propen-1-yl)-;Barbituric acid,5-allyl-5-(2-hydroxypropyl)-;2,4,6(1H,3H,5H)-Pyrimidinetrione,5-(2-hydroxypropyl)-5-(2-propenyl)-;5-(2-Hydroxypropyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione;Axeen;Ipronal;5-Allyl-5-(2-hydroxypropyl)barbituric acid;5-Allyl-5-(β-hydroxypropyl)barbituric acid;HH 184;Centralgyl;Proxibarbal;Centralgol;Hydroxydial;Proxibarbital;(±)-Ipronal;42013-34-3

Description

Proxibarbal is a member of barbiturates.|Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing immunoallergic thrombocytopenia.

Proxibarbal Basic Attributes

226.232

226.23

219-803-4

Y54BSX54CS|RE966VDY2Y

N - Nervous system

Characteristics

95.5

0.23760

1.2754 g/cm3

157-158 °C

1.493

LD50 intraperitoneal in mouse: 2500mg/kg

Safety Information

III

6.1(b)

UN 3249

Drug Information

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)

Axeen

Proxibarbal Use and Manufacturing

Uses

Relaxant (smooth muscle);analgesic; anti-inflammatory.

Pharmaceuticals

Computed Properties

Molecular Weight:226.23
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:226.09535693
Monoisotopic Mass:226.09535693
Topological Polar Surface Area:95.5
Heavy Atom Count:16
Complexity:331
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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