 Home > Encyclopedia > 3-Nitro-5-(trifluoromethyl)benzenamine

3-Nitro-5-(trifluoromethyl)benzenamine

3-Nitro-5-(trifluoromethyl)benzenamine structure

CAS No:
401-94-5
Formula:
C7H5F3N2O2
Chemical Name:
3-Nitro-5-(trifluoromethyl)benzenamine
Synonyms:
Benzenamine,3-nitro-5-(trifluoromethyl)-;m-Toluidine,α,α,α-trifluoro-5-nitro-;3-Nitro-5-(trifluoromethyl)benzenamine;3-Trifluoromethyl-5-nitroaniline;5-Trifluoromethyl-3-nitroaniline;3-Nitro-5-trifluoromethylaniline;3-Amino-5-nitrobenzotrifluoride
Categories:
Organic Chemistry > Organic Fluorine Compound

Request for Quotation

3-Nitro-5-(trifluoromethyl)benzenamine Basic Attributes

Molecular Weight：

206.12

Exact Mass：

206.12

DSSTox ID：

DTXSID00379667

HScode：

2921420090

Characteristics

PSA：

71.8

XLogP3：

Density：

1.5±0.1 g/cm3

Melting Point：

80-81.5 °C

Boiling Point：

280.7°C at 760 mmHg

Flash Point：

123.5±27.3 °C

Refractive Index：

1.525

Safety Information

Hazard category：

6.1

Transport codes：

2811

hazard class code：

20/21/22-36/37/38

safety instructions：

26-36/37/39-36

Marks：

Xi,Xn

Hazard note：

Irritant

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P403+P233, P405, P501

Hazard Statements：

H302

3-Nitro-5-(trifluoromethyl)benzenamine Use and Manufacturing

General procedure: A substituted aniline (3.0 mmol) and CDI (3.0 mmol) were dissolvedin anhydrous dichloromethane (15 mL) and the reaction was stirred atroom temperature for 1 h under a nitrogen atmosphere. The solvent wasthen removed under reduced pressure, yielding the crude carbamoylimidazolesas solids. The carbamoylimidazoles were then dissolved indichloromethane (5 mL), and added to a solution of amine 13a or 13b(2.0 mmol) in dichloromethane (15 mL). The reaction was then left tostir for 1 h at room temperature. Dichloromethane (50 mL) was thenadded, and the organic layer was washed with water (3×100 mL). Theorganic layer was dried over Na2SO4 and concentrated under reducedpressure. The product was purified on silica gel by step-wise gradientelution with dichloromethane/ethyl acetate (100:0 to 90:10).

Computed Properties

Molecular Weight:206.12
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Exact Mass:206.03031189
Monoisotopic Mass:206.03031189
Topological Polar Surface Area:71.8
Heavy Atom Count:14
Complexity:226
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 3-Nitro-5-(trifluoromethyl)benzenamine

Jinshu Peptide Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Distributor Supplier of peptone

Most professional factory direct supply high quality 3-Amino-5-nitrobenzotrifluoride

CAS No.: 401-94-5

Grade: Pharmaceutical Grade

Content: 99%

Inquiry

Latest News on 3-Nitro-5-(trifluoromethyl)benzenamine

Learn More Other Chemicals

4-(Trifluoromethyl)benzeneacetic acid

32857-62-8
3-BROMO-2-FLUORO-6-PICOLINE

375368-78-8
2,4-Diisopropylphenol

2934-05-6
1,2-Diiodotetrafluoroethane Formula

354-65-4
6-METHYL-2-PIPERIDINECARBOXYLICACID Formula

99571-58-1
2,4-Dichloro-6-picoline Formula

42779-56-6
1-BROMO-1H,1H,2H,2H-PERFLUORODECANE Structure

21652-57-3
Perfluorohexanoic acid Structure

307-24-4
What is 6-chloro-2-naphthalenethiol

392330-26-6
What is 2,3-Dichloro-5-nitropyridine

22353-40-8

Hot Searches: barium hydroxide; amitraz; formaldehyde formaldehyde; gluconic acid; bioglutide; remeron generic name

Guide of 3-Nitro-5-(trifluoromethyl)benzenamine

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

3-Nitro-5-(trifluoromethyl)benzenamine

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.