Opipramol
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Opipramol
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CAS No:
315-72-0
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Formula:
C23H29N3O
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Chemical Name:
Opipramol
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Synonyms:
1-Piperazineethanol,4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-;4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol;5H-Dibenz[b,f]azepine,1-piperazineethanol deriv.;G 33040;GR 33040;Endison;Opipramol;Opipramol G;Opramidol;N-[3-[4-(2-Hydroxyethyl)piperazino]propyl]iminostilbene;NSC 169867
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CAS No:
Description
Crystalline Solid
2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.|Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.|A tricyclic antidepressant with actions similar to AMITRIPTYLINE.
Opipramol Basic Attributes
363.5
363.50
206-254-0
D23ZXO613C
169867
DTXSID3023394
N - Nervous system
2933990090
Characteristics
30
3.24930
1.129 g/cm3
100.5 °C
555.1ºC at 760 mmHg
290.5ºC
1.6500 (estimate)
-20°C Freezer
Drug Information
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)|Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (See all compounds classified as Adrenergic Uptake Inhibitors.)
Hydrochloride, Opipramol
Computed Properties
Molecular Weight:363.5
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:363.231062557
Monoisotopic Mass:363.231062557
Topological Polar Surface Area:30
Heavy Atom Count:27
Complexity:448
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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