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Home > Biochemical Engineering
Biochemical engineering transforms laboratory findings from biotechnology into industrial-scale production processes. This field, often termed biochemical engineering, encompasses various facets such as fermentation engineering, large-scale cultivation of animal and plant cells, enzyme engineering, biochemical reaction engineering, downstream engineering (biological separation engineering), biological functional elements (like enzyme electrodes), and the control and optimization of biochemical techniques. Biochemical engineering emerges from merging modern biotechnology with conventional chemical technology, and it is a discipline that successfully applies the principles and methods of chemical engineering to the industrial development of biotechnology laboratories.

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11217 Biochemical Engineering items

(-)-Pimecrolimus

CAS No: 137071-32-0

Formula: C43H68ClNO11

Categories: Biochemical Engineering > Inhibitors

Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12.Target: OthersPimecrolimus blocks T-lymphocyte activation pathway by inhibiting calcineurin function [1]. Pimecrolimus prevents the release of cytokines and pro-inflammatory mediators from mast cells. Pimecrolimus binds to macrophilin-12, the pimecrolimusmacrophilin complex then binds to the cytosolic enzyme calcineurin phosphatase. The pimecrolimus-macrophilin complexMore

Bupivacaine hydrochloride

CAS No: 18010-40-7

Formula: C18H28N2O.ClH

Categories: Biochemical Engineering > Inhibitors

ChEBI: A racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. The monohydrate form is commonly used as a local anaesthetic.More

Lafutidine

CAS No: 118288-08-7

Formula: C22H29N3O4S

Categories: Biochemical Engineering > Inhibitors

Lafutidine is a second generation of H2-receptor antagonist. H2-receptor antagonist can strongly inhibit gastric acid secretion compared with conventional drugs such as antacids. Unlike conventional H2-receptor antagonist, lafutidine inhibits gastric acid secretion during daytime as well as nighttime in clinical studies in humans. Lafutidine also has gastroprotective activity independent of its acid antisecretory efficacy, preventing noxious agent-induced gastric mucosal injury and acceleratingMore

FMOC-L-asparagine

CAS No: 71989-16-7

Formula: C19H18N2O5

Categories: Biochemical Engineering > Amino Acids and Derivatives

white to light yellow crystal powdeMore

Deoxynojirimycin

CAS No: 19130-96-2

Formula: C6H13NO4

Categories: Biochemical Engineering > Blood Glucose Regulators

1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes oMore

Glucamine

CAS No: 488-43-7

Formula: C6H15NO5

Categories: Biochemical Engineering > Hair Conditioning

Crystalline SolidMore

Vardenafil

CAS No: 224785-90-4

Formula: C23H32N6O4S

Categories: Biochemical Engineering > Inhibitors

Vardenafil is a PDE5 inhibitor used for treating erectile dysfunction.Target: PDE5Vardenafil specifically inhibited the hydrolysis of cGMP by PDE5 with an IC50 of 0.7 nM (6.6 nM). In contrast, the IC50 of vardenafil for PDE1 was 180 nM; for PDE6, 11 nM; for PDE2, PDE3 and PDE4, more than 1000 nM. Relative to PDE5, the ratios of the IC50 for PDE1 were 257 (60), for PDE6 16 (7.4). Vardenafil significantly enhanced the SNP-induced relaxation of human trabecular smooth muscle at 3 nM (10 nM)More

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D-Isoleucine

CAS No: 319-78-8

Formula: C6H13NO2

Categories: Biochemical Engineering > Amino Acids and Proteins

white to very slightly yellow powderMore

1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo-, sodium salt (1:2)

CAS No: 122628-50-6

Formula: C14H6N2O8.2Na

Categories: Biochemical Engineering > Antioxidant Ingredient

Methoxatin (disodium salt) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy.Target:Methoxatin has been isolated from guinea-pig neutrophils. The presence of Methoxatin in guinea-pig neutrophils and suggest that it has a possible role, direct or indirect, in the O2.(-)-producing respiratory burst. More

Trelagliptin

CAS No: 865759-25-7

Formula: C18H20FN5O2

Categories: Biochemical Engineering > Inhibitors

Trelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). IC50 value:Target: DPP4Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-dailMore

Chrysophanol

CAS No: 481-74-3

Formula: C15H10O4

Categories: Biochemical Engineering > Plant Extracts

Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. More

Corosolic acid

CAS No: 4547-24-4

Formula: C30H48O4

Categories: Biochemical Engineering > Biosynthetic Natural Products

Corosolic acid isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.IC50 value: 26.8 μg/ml in vitroTarget:In vitro: Corosolic acid displayed about the same potent cytotoxic activity as ursolic acid against several human cancer cell lines. In addition, the compound displayed antagonistic activity against the phorbol ester-induced morphological modification of K-562 leukemic cells, indicating the suppression of protein kinase C (PKC) activMore

L-Selenomethionine

CAS No: 3211-76-5

Formula: C5H11NO2Se

Categories: Biochemical Engineering > Amino Acids and Derivatives

L-SelenoMethionine is a major natural food-form of selenium.Target:The median lethal dose (LD50) of L-SelenoMethionine in rats given an intraperitoneal injection was determined to 4.25 mg Se/kg body and thus is comparable to that of selenite or selenate. In mice, the LD50 of L-SelenoMethionine was 8.8 ± 1.37 mg Se/kg, and the minimal lethal dose, 4.0 mg Se/kg, after intravenous injection. More

Baicalein

CAS No: 491-67-8

Formula: C15H10O5

Categories: Biochemical Engineering > Chinese Herbs

Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM. More

Telaprevir

CAS No: 402957-28-2

Formula: C36H53N7O6

Categories: Biochemical Engineering > Inhibitors

Telaprevir is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide. More

Frequently Asked Questions

What are the applications of biochemical engineering?

Biochemical engineering has wide-ranging applications, including the industrial production of enzymes, vaccines, antibiotics, and biofuels; environmental protection through wastewater treatment and bioremediation; and fermentation processes in the food and beverage industry.

What is biochemical oxygen demand (BOD)?

Biochemical Oxygen Demand (BOD) measures the amount of oxygen consumed by biochemical reactions in water, serving as an indicator of organic pollutant levels. For example, sewage discharge can raise BOD, reducing oxygen availability and harming aquatic life. Biochemical engineers use biochemical techniques and treatment processes to reduce BOD, ensuring safer water ecosystems and supporting environmental sustainability.

Biochemical engineering vs biomedical engineering?

Biochemical engineering focuses on applying biochemical reactions and techniques for industrial-scale production of biological products. In contrast, biomedical engineering combines engineering principles with medical sciences, concentrating on designing medical devices, diagnostic tools, and therapies. While biochemical engineering emphasizes industrial bio-product production, biomedical engineering aims to improve healthcare outcomes through technology.

What is biochemical engineering?

Biochemical engineering is a branch of engineering that emerged in the 1980s, focusing on the large-scale production of biochemical products. It integrates principles from biology, chemistry, and engineering to study biochemical reactions and techniques. This field investigates intracellular components such as proteins, sugars, lipids, and nucleic acids, which are essential for producing various biological substances, including enzymes, vaccines, and biofuels.

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