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Flavonoids

Quercitrin

(522-12-3)
Has been used as textile dye.Flavine yellow shade is prepared by extracting quercitron bark with high pressure steam and consists mainly of quercitrin:Tisdale, Can. Text. J. 57, 44 (1941).

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Acacetin

(480-44-4)
VEGF expression inhibitor and tumor angiogenesis. A flavonoid with antiaggregatory activity in human blood.

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Amentoflavone

(1617-53-4)
Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects.IC50 value:Target:In vitro: In irradiated v79 cells, Pretreatment with amentoflavone 24 hours prior to 8 Gy 60Co γ-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass [2]. Amentoflavone dose-dependently inhibited the viability of SW480 cells, and a high concent

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Linarin

(480-36-4)
Monanthoside has anti-staphylococcus aureus and hemolytic streptococcus, anti-aging effect, anti-hypoxia effect, anti-adverse stimulus effect, two-way regulation effect on the body, anti-fatigue effect, inhibiting blood sugar rise, toxicity and mutagenicity Research on teratogenicity and its effect on learning and memory. The anthocyanin has anti-aging, anti-anoxia, anti-adverse stimulus, two-way regulation of the body, anti-fatigue, inhibiting blood sugar rise, toxicity and mutagenicity and te

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Gallocatechin

(970-73-0)
(+)-Gallocatechin is a polyphenol compound from green tea, possesses anticancer activity[1].

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Calycosin

(20575-57-9)
Calycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.IC50 value:Target: in vitro: calycosin had obvious anti-proliferation effects on SKOV3 cells in a dose- and time-dependent manner. calycosin up-regulated the Bax/Bcl-2 ratio and cleaved caspase-3, cleaved caspase-9 expression in a dose-dependent manner. In summary, calycosin might exert anti-growth and induce-apoptosis activity against ovarian cancer SKOV3 cells through activating caspase

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Myricitrin

(17912-87-7)
It was isolated from the leaves of Myrtus communis an inhibitory activity against nifuroxazide, aflatoxine B1 and H2O2 induced mutagenicity. Antioxidant

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Icariside II

(113558-15-9)
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

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Oroxylin A

(480-11-5)
Oroxylin A is a natural active flavonoid with strong anticancer effects.IC50 value:Target:In vitro: Oroxylin A suppressed the MDM2-mediated degradation of p53 via downregulating MDM2 transcription in wt-p53 cancer cells [1]. Oroxylin A remarkably reduced the generation of lactate and glucose uptake under hypoxia in HepG2 cells, inhibited HIF-1α expression and its stability [2]. Oroxylin A promotes superoxide dismutase (SOD2) gene expression through SIRT3-regulated DNA-binding activity of

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Flavonoids, also known as bioflavonoids (bioflavonoids), are a type of compound that exists in nature and has a 2-phenyl flavonone structure. Widely distributed in the plant kingdom, it is a large class of important natural compounds. Flavonoids mostly have colors, and their different colors add more colors to the family of natural pigments.

Frequently Asked Questions

What are flavonoids and why are they important?

Flavonoids are a diverse group of phytonutrients found in almost all fruits and vegetables. They are known for their antioxidant, anti-inflammatory, and immune-supporting properties. Common subclasses include flavones, flavonols, flavanones, isoflavones, and anthocyanidins. Due to their health-promoting effects, flavonoids are widely used in dietary supplements, functional foods, and natural therapeutics.

What are the common natural sources of flavonoids?

Flavonoids occur naturally in a wide variety of plant-based foods and beverages. Rich sources include citrus fruits (flavanones), berries (anthocyanidins), onions and apples (flavonols), soybeans (isoflavones), and tea—especially green and black tea (catechins and theaflavins). Including a colorful diet with diverse fruits, vegetables, legumes, and herbs helps ensure adequate flavonoid intake.

What should buyers consider when sourcing high-quality flavonoid extracts?

When sourcing flavonoid extracts, buyers should evaluate:1. Purity and concentration levels (e.g., HPLC-certified assays).2. Botanical origin and extraction method (e.g., solvent-free or ethanol-based).3. Compliance with regulatory standards like ISO, GMP, or FDA GRAS status.4. Supplier transparency regarding heavy metals, pesticides, and microbial testing.5. Batch-to-batch consistency and documentation (Certificates of Analysis).These factors ensure safety, efficacy, and suitability for end-use applications.

Are there different types of flavonoid compounds used commercially?

Yes, several flavonoid compounds are commonly used in commercial products. Key examples include quercetin (a flavonol with strong antioxidant activity), hesperidin (a citrus flavanone supporting vascular health), epigallocatechin gallate (EGCG from green tea, known for metabolism support), genistein (a soy isoflavone used in hormonal health formulations), and rutin (used for capillary strength and anti-edema effects). Each type offers distinct biological activities and application benefits.

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