Hypercalcemia
Hypercalcemia refers to an abnormal increase in serum ionized calcium concentration. When the amount of calcium entering the extracellular fluid (intestines, bones) exceeds the amount of calcium excreted (intestines, kidneys), hypercalcemia occurs, and the blood calcium concentration is higher than 2.75mmol/L. There are two major causes of hypercalcemia: PTH-dependent and PTH-independent hypercalcemia. It is generally believed that when serum calcium is above 3.75mmol/L, hypercalcemic crisis may occur, which is life-threatening if not properly handled and is a clinical emergency.
Related Drugs
Ibandronate
Indication: This product is suitable for hypercalcemia caused by malignant tumors with or without bone metastasis: used to treat bone pain caused by osteolytic bone metastasis of malignant tumors.
Manufacturer:
Nanjing Hencer Pharmaceutical Co., Ltd.
Pamidronate Disodium Injection
Indication: Hypercalcemia and bone destruction and dissolution caused by malignant tumors and their bone metastases, eliminate pain, improve exercise ability, reduce pathological fractures, and reduce patients' requirements for radiotherapy. It can delay the development of osteolytic lesions, but has no effect on related complications (such as fractures and mortality). Bone lesions of Paget's disease and osteoporosis caused by various reasons
Manufacturer:
Zhejiang Jinhua Aotuokang Pharmaceutical Group Inc. Co.
Pamidronate Disodium Injection
Indication: Hypercalcemia and bone destruction and dissolution caused by malignant tumors and their bone metastases, eliminate pain, improve exercise ability, reduce pathological fractures, and reduce patients' requirements for radiotherapy. It can delay the development of osteolytic lesions, but has no effect on related complications (such as fractures and mortality). Bone lesions of Paget's disease and osteoporosis caused by various reasons
Manufacturer:
Qingdao Jinfeng Pharmaceutical Co., Ltd.
Zoledronic acid injection
Indication: Bone pain caused by osteolytic bone metastases of malignant tumors, hypercalcemia caused by malignant tumors.
Manufacturer:
Chengdu Tiantai Mountain Pharmaceutical Co., Ltd.
Sodium dihydrogen phosphate
Indication: 1. Used for the prevention and treatment of hypophosphatemia. It is also used as a phosphorus additive in total intravenous hypernutrient therapy to prevent hypophosphatemia. 2. As an auxiliary medication for urinary tract infection, this drug can acidify urine, thereby enhancing the antibacterial activity of methenamine mandelate and methenamine hippurate, and can eliminate the odor and turbidity of ammonia-containing urine during urinary tract infection. 3. Prevention of calcium-containing kidney stones. This drug can acidify urine, increase the solubility of calcium, and prevent calcium deposition in urine, thereby preventing the recurrence of calcium-containing kidney stones. 4. Treatment of hypercalcemia. In recent years, this drug has not been commonly used to treat hypercalcemia, and other safer and more effective methods have been used.
Manufacturer:
Hunan Warrant Chiral Pharmaceutical Co., Ltd.
Disodium Clodronate for Injection
Indication: 1. Hypercalcemia complicated by malignant tumors. 2. Bone pain caused by osteolytic cancer metastasis. 3. Can prevent or delay osteolytic bone metastasis of malignant tumors. 4. Various types of osteoporosis.
Manufacturer:
Hainan Lingkang Pharmaceutical Co., Ltd.
Pamidronate disodium
Indication: Hypercalcemia complicated by malignancy and bone pain caused by osteolytic cancer metastasis.
Manufacturer:
Hubei Wushi Pharmaceutical Co., Ltd.
Pamidronate disodium
Indication: Hypercalcemia complicated by malignancy and bone pain caused by osteolytic cancer metastasis.
Manufacturer:
Sichuan Tiandao Pharmaceutical Co., Ltd.
Pamidronate disodium
Indication: Hypercalcemia complicated by malignancy and bone pain caused by osteolytic cancer metastasis.
Pamidronate disodium
Indication: Hypercalcemia complicated by malignancy and bone pain caused by osteolytic cancer metastasis.
Manufacturer:
Fuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd.