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Onychomycosis
Onychomycosis is an infection of the nails caused by dermatophytes, yeasts and non-dermatophyte filamentous fungi (molds). The nail disease caused by dermatophytes infecting the nail plate alone is called tinea unguium. Tinea unguium is mostly directly transmitted by tinea pedis, while tinea fingernails may be transmitted by tinea manuum or directly infected by scratching tinea in other parts of the body. Tinea unguium is commonly known as "onychomycosis" and is called chicken claw wind or putty nails in traditional Chinese medicine. It is mostly caused by the long-term spread of tinea manuum and tinea pedis, which leads to the loss of nail health.
  • Site of disease:

    Hands and feet
  • Infectious :

    Contagious
  • Frequent population:

    Diabetes, low immunity, malnutrition...
  • Related symptoms:

    Thickened nails Yellow nails Red or black spots on nails Mica-like nails Brittle nails
  • Concurrent disease:

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TERBINAFINE- terbinafine hydrochloride_tablet
Indication: Terbinafine tablets are indicated for the treatment of onychomycosis of the toenail or fingernail due to dermatophytes (tinea unguium). Terbinafine tablets, are an allylamine antifungal indicated for the treatment of onychomycosis of the toenail or fingernail due to dermatophytes (tinea unguium).
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ITRACONAZOLE_- itraconazole_capsule
Indication: Itraconazole capsules immunocompromised and non-immunocompromised 1. Blastomycosis, pulmonary and extrapulmonary 2. Histoplasmosis, including chronic cavitary pulmonary disease and disseminated, non- meningeal histoplasmosis, and 3. Aspergillosis, pulmonary and extrapulmonary, in patients who are intolerant of or who are refractory to amphotericin B therapy. Specimens for fungal cultures and other relevant laboratory studies (wet mount, histopathology, serology) should be obtained before therapy to isolate and identify causative organisms. Therapy may be instituted before the results of the cultures and other laboratory studies are known; however, once these results become available, antiinfective therapy should be adjusted accordingly. Itraconazole capsules non-immunocompromised 1. Onychomycosis of the toenail, with or without fingernail involvement, due to dermatophytes (tinea unguium), and 2. Onychomycosis of the fingernail due to dermatophytes (tinea unguium). Prior to initiating treatment, appropriate nail specimens for laboratory testing (KOH preparation, fungal culture, or nail biopsy) should be obtained to confirm the diagnosis of onychomycosis. (See CLINICAL PHARMACOLOGY: Special Populations, CONTRAINDICATIONS, WARNINGS, and ADVERSE REACTIONS: Postmarketing Experience for more information.) Description of Clinical Studies: Blastomycosis: Analyses were conducted on data from two open-label, non-concurrently controlled studies (N=73 combined) in patients with normal or abnormal immune status. The median dose was 200 mg/day. A response for most signs and symptoms was observed within the first 2 weeks, and all signs and symptoms cleared between 3 and 6 months. Results of these two studies demonstrated substantial evidence of the effectiveness of itraconazole for the treatment of blastomycosis compared with the natural history of untreated cases. Histoplasmosis: Analyses were conducted on data from two open-label, non-concurrently controlled studies (N=34 combined) in patients with normal or abnormal immune status (not including HIV-infected patients). The median dose was 200 mg/day. A response for most signs and symptoms was observed within the first 2 weeks, and all signs and symptoms cleared between 3 and 12 months. Results of these two studies demonstrated substantial evidence of the effectiveness of itraconazole for the treatment of histoplasmosis, compared with the natural history of untreated cases. Histoplasmosis in HIV-infected patients: Data from a small number of HIV-infected patients suggested that the response rate of histoplasmosis in HIV-infected patients is similar to that of non-HIV-infected patients. The clinical course of histoplasmosis in HIV-infected patients is more severe and usually requires maintenance therapy to prevent relapse. Aspergillosis: Analyses were conducted on data from an open-label, “single-patient-use” protocol designed to make itraconazole available in the U.S. for patients who either failed or were intolerant of amphotericin B therapy (N=190). The findings were corroborated by two smaller open-label studies (N=31 combined) in the same patient population. Most adult patients were treated with a daily dose of 200 to 400 mg, with a median duration of 3 months. Results of these studies demonstrated substantial evidence of effectiveness of itraconazole as a second-line therapy for the treatment of aspergillosis compared with the natural history of the disease in patients who either failed or were intolerant of amphotericin B therapy. Onychomycosis of the toenail: Analyses were conducted on data from three double-blind, placebo-controlled studies (N=214 total; 110 given itraconazole capsules Onychomycosis of the fingernail: Analyses were conducted on data from a double-blind, placebo-controlled study (N=73 total; 37 given itraconazole capsules
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TAVABOROLE- tavaborole_solution
Indication: Tavaborole topical solution, 5% is an oxaborole antifungal indicated for the treatment of onychomycosis of the toenails due to Trichophyton rubrum Trichophyton mentagrophytes Tavaborole topical solution is an oxaborole antifungal indicated for the topical treatment of onychomycosis of the toenails due to Trichophyton rubrum Trichophyton mentagrophytes 1.
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Indication: Purpose
Antifungal
Use
This product facilitates the recovery of nailsinfluenced by nail fungus and aids in avertingrecurrent athlete''s foor through daily usage.lteffectively targets diverse conditions likeomychomycosis, atrophy, uneven surfacesmstratification, nail thickening, yellowing, nailremoval, turbidity, discoloration, and other nailirregulartes.Beyondresoling these concerns,our product goes further by nurturing nails,encouraging their natural repair process, andgently reinstating theirinnate smoothness andluster.
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TERBINAFINE HYDROCHLORIDE- terbinafine hydrochloride_tablet
Indication: Terbinafine Hydrochloride Tablets are indicated for the treatment of onychomycosis of the toenail or fingernail due to dermatophytes (tinea unguium) (see DOSAGE AND ADMINISTRATION CLINICAL STUDIES Prior to initiating treatment, appropriate nail specimens for laboratory testing (KOH preparation, fungal culture, or nail biopsy) should be obtained to confirm the diagnosis of onychomycosis.
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