Tetracycline antibiotics. This product is a broad-spectrum antibacterial agent with bactericidal effects at high concentrations. Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria, and spirochetes are also sensitive to this product. This product is more effective against Gram-positive bacteria than Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, and Yersinia are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant Neisseria gonorrhoeae is also resistant to doxycycline. Due to the widespread use of tetracyclines over the years, common clinical pathogens have become seriously resistant to this product, including Gram-positive bacteria such as Staphylococcus and most Gram-negative bacilli.

This product is an intermediate in the synthesis of Schisandrae Chinensis A, which can reduce liver damage and alanine aminotransferase (ALT) elevation caused by carbon tetrachloride; inhibit liver microsomal lipid peroxidation caused by carbon tetrachloride, carbon tetrachloride metabolism into carbon monoxide, and reduce the consumption of reduced coenzyme II and oxygen, thereby protecting the structure and function of liver cell biomembrane; can reduce prednisone-induced liver ALT elevation, promote liver regeneration in mice with partial hepatectomy; has a significant induction effect on cytochrome P450 enzyme activity, enhances the detoxification ability of carbon tetrachloride and certain carcinogens; improves protein metabolism in some hepatitis patients, increases albumin and reduces globulin. It has no negative conversion effect on HbsAg and HbeAg, and cannot shrink enlarged liver and spleen.

This product belongs to the benzamide antipsychotic drug. Its characteristic action is to selectively block the dopamine (DA2) receptors of the mesolimbic system, with little effect on other neurotransmitter receptors, mild anticholinergic effect, and no obvious sedative and anti-excitement and agitation effects. This product also has strong antiemetic and gastric juice secretion inhibitory effects.

It has the effect of competitively blocking the binding of histamine to H2 receptors and inhibiting the effect of gastric acid. Its molarity is 5 to 12 times that of cimetidine, making it a potent H2 receptor blocker.

This product belongs to the macrolide antibiotics, which is the dodecyl sulfate of erythromycin propionate. It has antibacterial activity against Staphylococcus, various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. may also be sensitive to this product. This product also has antibacterial activity against various anaerobic bacteria except Bacteroides fragilis and Fusobacterium; it also has inhibitory effects on Legionella, Campylobacter fetus, some spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product is an antibacterial agent, but it also has a bactericidal effect on some bacteria at high concentrations. This product can pass through the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site (P site), blocking the transfer RNA (t-RNA) binding to the P site, and also blocking the displacement of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis. This product is only effective against bacteria with active division.