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Nicergoline Tablets

Function and Efficacy

This product is a semi-synthetic ergot alkaloid derivative. It has alpha-receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It promotes the conversion of the neurotransmitter dopamine to increase nerve conduction, strengthen the synthesis of brain protein, and improve brain function. This product is a semi-synthetic ergot alkaloid derivative. It has alpha-receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It promotes the conversion of the neurotransmitter dopamine to increase nerve conduction, strengthen the synthesis of brain protein, and improve brain function.

Ingredients

Main ingredients: The main ingredient of this product is nicergoline, and its chemical name is: 10α-methoxy-1,6-dimethylergoline-8β-methanol-5-bromonicotinate.

Name Description Content CAS NO. Manufacturer
NicergolineIngredients

This product is a semi-synthetic ergot alkaloid derivative. It has alpha-receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It promotes the conversion of neurotransmitter dopamine to increase nerve conduction, strengthens the synthesis of brain protein, and improves brain function.

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27848-84-6 35

Appearance

This product is a sugar-coated tablet, which appears white or off-white after removing the sugar coating.

Indication

1. Improve low desire and emotional disorders (slow reaction, lack of concentration, memory loss, lack of ideas, depression, anxiety, etc.) caused by cerebral arteriosclerosis and sequelae of cerebral stroke. 2. Acute and chronic peripheral circulatory disorders (limb vascular occlusive disease, Raynaud's syndrome, other symptoms of poor peripheral circulation). It is also suitable for vascular dementia, especially in the early stage of treatment, it can improve cognition, memory, etc., and can reduce the severity of the disease.

Usage and Dosage

Oral administration, do not chew. 20~60mg (2~6 tablets) per day, divided into 2-3 doses. Continue to administer for a sufficient period of time, at least six months, and the doctor will decide whether to continue the administration.

Adverse Reactions

No serious adverse reactions have been reported. There may be hypotension, dizziness, stomach pain, hot flashes, facial flushing, drowsiness, insomnia, etc. In clinical trials, an increase in uric acid concentration in the blood was observed, but this phenomenon was not related to the dosage and administration time.

Precautions

This product is not suitable for the following situations: recent myocardial infarction, acute bleeding, severe bradycardia, orthostatic regulation dysfunction, bleeding tendency and allergy to nicergoline.

Special Population Medication

Precautions for children: According to the current indications, this drug is not for children. Precautions for pregnancy and lactation: Toxicity tests failed to show the teratogenic effect of nicergoline. The indications of this drug show that this drug is not for pregnant and lactating women. Precautions for the elderly: Pharmacokinetic and tolerability tests show that there is no difference in dosage and administration method between adults and elderly patients.

Drug Interactions

Nicergoline tablets may enhance the effects of antihypertensive drugs. Since nicergoline is metabolized by CYTP4502D6, interactions with drugs that are metabolized by the same pathway cannot be ruled out.

Storage

Keep away from light and store in airtight container.

Packaging Specification

10 mg

Validity Period

36 months.

Manufacturer

Hainan Zambon Pharmaceutical Co., Ltd.

  • Founded in:

    1988-10-12
  • Address:

    No. 20, Keyuan Road, Haikou City, Hainan Province
  • Tax NO.:

    9146000062000917X7
  • Registered Funds:

    7 million yuan
  • Website:

  • Email:

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