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Amoxicillin Sodium for Injection

Function and Efficacy

Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.

Ingredients

The main ingredient of this product is amoxicillin sodium. Its chemical name is (2S,5R,6R)-3,3-dimethyl-6-[(R)-(-)-2-amino-2-(4-hydroxyphenyl)acetylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane. Molecular formula: C16H18N3NaO5S. Molecular weight: 387.40

Name Description Content CAS NO. Manufacturer
Amoxicillin sodiumIngredients

Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.

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34642-77-8 16

Appearance

This product is white or off-white powder or crystal.

Indication

It is suitable for patients with the following infections caused by sensitive bacteria (non-β-lactamase strains) who need hospitalization or cannot take oral medicine: upper respiratory tract infection, urogenital tract infection, skin and soft tissue infection, lower respiratory tract infection, etc. This product can also be used to treat typhoid fever and leptospirosis.

Usage and Dosage

Intramuscular injection or intravenous drip after dilution. Adults take 0.5-1g once, once every 6-8 hours (3-4 times a day). Children take 50-100mg/kg per day based on body weight, divided into 3-4 doses. For other details, see the instructions.

Adverse Reactions

1. Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis. 2. Allergic reactions such as rash, drug fever and asthma. 3. Anemia, thrombocytopenia, eosinophilia, etc. 4. Serum aminotransferase may be slightly elevated. 5. Superinfection caused by Candida or drug-resistant bacteria. 6. Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior may occur.

Precautions

Contraindicated in patients with penicillin allergy or penicillin skin test positive

Drug Interactions

1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but their clinical significance is unclear.

Storage

Keep in dark place and sealed

Packaging Specification

2.0g (calculated as C16H19N3O5S)

Manufacturer

Shandong Lukang Pharmaceutical Co., Ltd.

  • Founded in:

    1993-02-15
  • Address:

    No. 88, Deyuan Road, Jining High-tech Zone, Shandong Province
  • Tax NO.:

    913700001659297311
  • Registered Funds:

    880.229735 yuan
  • Website:

  • Email:

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