High Quality Light Yellow Oil Latanoprost CAS 130209-82-4 with best price and fast delivery

Latanoprost More Info

Latanoprost is a prostaglandin analog used primarily in the treatment of elevated intraocular pressure (IOP) associated with conditions such as glaucoma and ocular hypertension. It is marketed under the brand name Xalatan and is administered as an ophthalmic solution.

Mechanism of Action

Latanoprost acts as a selective agonist at the FP receptor, which is a subtype of prostaglandin receptors. Its primary mechanism involves:
Increasing Aqueous Humor Outflow: Latanoprost enhances the outflow of aqueous humor through the uveoscleral pathway, thereby reducing IOP. This mechanism is crucial since elevated IOP is a significant risk factor for optic nerve damage and visual field loss in glaucoma patients.
Prodrug Conversion: Upon topical application, latanoprost is converted into its active form, latanoprost acid, which is responsible for its therapeutic effects. Peak concentrations in the aqueous humor are typically reached about 2 hours after administration, with IOP reduction beginning approximately 3–4 hours post-application and peaking at 8–12 hours.

Applications

Latanoprost is indicated for:
Open-Angle Glaucoma: To lower elevated IOP in patients diagnosed with this condition.
Ocular Hypertension: Effective in managing high IOP not associated with glaucoma.

Routes of Administration

Latanoprost is administered topically to the eye as an ophthalmic solution. The typical dosage is one drop in the affected eye(s) once daily, preferably in the evening.

Safety and Side Effects

Common Side Effects
Patients using latanoprost may experience several side effects, including:
Eye Irritation: Symptoms such as burning, stinging, or redness.
Changes in Eye Color: Increased pigmentation of the iris, particularly in individuals with lighter-colored eyes.
Eyelash Changes: Lengthening, thickening, and darkening of eyelashes.
Blurred Vision: Temporary visual disturbances may occur.
Serious Side Effects
More severe reactions can include:
Allergic Reactions: Signs such as hives, difficulty breathing, or swelling of the face and throat require immediate medical attention.
Macular Edema: Accumulation of fluid in the macula can lead to vision impairment.
Severe Eye Infections: Symptoms such as eye swelling or discharge may indicate infection.

Pharmacokinetics

Absorption and Distribution
Latanoprost is well absorbed through the cornea after topical administration. The prodrug form is hydrolyzed to its active acid form upon absorption, achieving peak concentrations in the aqueous humor within 2 hours.
Metabolism and Excretion
The active form of latanoprost undergoes rapid metabolism primarily in the liver via fatty acid beta oxidation. The elimination half-life is approximately 17 minutes. Most metabolites are excreted through urine, with about 88% of the topical dose recovered.
Special Considerations
Patients using latanoprost should be aware that changes in eye color and eyelash appearance may be permanent. It is also important to advise patients to avoid using latanoprost if they are allergic to it or any components of its formulation.

Package Image

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.