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Brief Introduction to Minoxidil
Minoxidil, also known as long pressure, minoxidil, molecular formula and relative molecular mass C9H15N5O = 209.25, is a white or off-white crystalline powder, slightly soluble in ethano*, slightly soluble in acetone. Can act directly on the blood vessel wall, dilate small arteries, reduce peripheral resistance, so that the blood pressure drop, can also increase the heart rate and cardiac output, but its antihypertensive effect is more significant than hydralazine and long-lasting.
Pharmacological effects
Minoxidil directly dilates small arteries, thus lowering Chemicalbook pressure, but the specific mechanism is not known. This product does not dilate small veins. Peripheral vascular resistance reduction caused by reflex heart rate acceleration, cardiac output increased. After lowering the pressure, renin activity increases, causing water and sodium retention. This product does not interfere with the vasomotor reflex, so upright hypotension does not occur. Minoxidil is a commonly used and effective drug for the treatment of hair loss, but its pharmacological action and its action of the target cells, but not very clear, in recent years, studies have shown that minoxidil may be through the following multiple pathways to promote hair growth.