99% Purity Ivermectin Powder 70288-86-7 Safe Customs Clearance

Ivermectin acts as a white or slightly yellow crystalline powder, soluble in methanol, esters, and aromatic hydrocarbons, insoluble in water. Ivermectin, also known as Ivermectin in English, is an antibiotic drug that has bactericidal activity against nematodes, insects, and mites. Injections and tablets made from Ivermectin are mainly used to treat gastrointestinal nematode disease, cowhide fly maggots, stripe fly maggots, sheep nose fly maggots, and pig and sheep scabies. In addition, ivermectin can also be used to treat parasitic nematodes in poultry, such as roundworms and lung nematodes. It can also be made into agricultural insecticides and acaricides, used to kill mites, diamondback moths, cabbage caterpillars, leaf miner flies, psyllids, nematodes, etc. that widely parasitize plants. The prominent feature of this drug is that it has mild side effects and can kill multiple parasites both inside and outside the body with a single dose. Plant based pesticide Ivermectin Ivermectin is a plant-based pesticide made by grinding, dissolving, adding additives and penetrating agents to various plants and Chinese herbal medicines such as cowpea seeds and bitter bean grass. The mechanism of action is mainly based on contact killing, supplemented by stomach toxicity, which promotes plant growth. It can be used to control all kinds of aphids and leaf eating pests. Dilute 1000~2000 times of water with spray, and the control effect is more than 98%. This drug belongs to the new generation of plant insecticides with low toxicity, low residue, and no harm to humans, animals, and the environment. Its insecticidal mechanism is to inhibit chitin synthesis in insect epidermis. Imidaclopramide is mainly a stomach toxin, but it can also invade insect cuticles and have an effect. The prevention and control of leaf eating pests have the advantages of special mechanism of action, good control effect, long residual period, low control cost, resistance to rainwater, low resistance of pests to drugs, and safety of plants, humans, animals, natural enemies, and the environment. The instructions for ivermectin [pharmacological effects] have a killing effect on microfilaments, but the exact mechanism is not clear. This product may act as an agonist of the neurotransmitter gamma tyrosine (GABA), disrupting the GABA-mediated synaptic transmission process in the central nervous system, leading to paralysis and death of the insect's nervous system. Although this product has no effect on adult worms, it can affect the normal development of microfilaments in the female uterus and inhibit their release from the pregnant uterus. Ivermectin has a slower and more persistent effect on microfilaments than ethambutol. It can quickly reduce the number of microfilaments in the patient's skin, but its effect on microfilaments in the patient's cornea and anterior chamber is relatively slow, and the decrease in microfilament number in this area is quite slow. After oral administration, the blood drug concentration reaches its peak at 4 hours, with T1/2 at 10 hours. Animal experiments have shown that only 1-2% of the oral dose appears in the urine as the prototype drug, while the rest is excreted from the feces. The drug concentration in the liver and adipose tissue is very high and cannot pass through the blood-brain barrier. The drug concentration in GABA containing nerve cells in mammals is very low, so the central nervous system response after medication is rare. [Indications] are the main drugs used to treat filariasis. [Dosage and Administration] Oral administration. Take it one hour before meals. The usual dosage for treating panococcal filariasis is 0.15-0.2mg/kg based on body weight, once every 6-12 months, depending on symptoms and the recurrence time of microfilaments. It can prevent further development of eye lesions (mostly caused by microfilaments), but because this product cannot kill adult insects, it cannot be cured. [Preparation and Specifications] Ivermectin Tablets 6mg [Adverse Reactions] Uninfected humans and other mammals have good tolerance to this product. Animals may experience drowsiness, dyskinesia, dilated pupils, tremors, and other reactions after receiving high doses, and excessive doses can lead to death. The side effects of medication in patients with panococcal filariasis are brief and mild, mostly limited to rash or itching (caused by death of intradermal microfilaments), and lymph node lesions (swelling and pain, seen in the neck, axilla, groin, and other areas). Rare dizziness, orthostatic hypotension (fainting), fever, headache, joint pain, fatigue, etc. The eye lesions did not worsen. Occasional changes in electrocardiogram, the significance of which is unclear. No carcinogenic or teratogenic effects. The side effects of medication in patients with panococcal filariasis are brief and mild, mostly limited to rash or itching (caused by death of intradermal microfilaments), and lymph node lesions (swelling and pain, seen in the neck, axilla, groin, and other areas). Rare dizziness, orthostatic hypotension (fainting), headache, joint pain, fatigue, etc. The eye lesions did not worsen. Occasional changes in electrocardiogram, the significance of which is unclear. No carcinogenic or teratogenic effects