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4-Bromoanisole CAS:104-92-7

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Unit Price: Get Latest Price
CAS No.:

104-92-7

Grade:

Industrail Grade

Content:

99%

Port:

SHJANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2025-12-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    4-Bromoanisole Basic information
    Product Name: 4-Bromoanisole
    Synonyms: p-methoxyphenylbromide;2-Bromoanisole,98%;4-Bromomethoxybenzene;4-Methoxy-1-bromobenzene;4-Methoxybromobenzene;4-Methoxyphenyl bromide;4-methoxyphenylbromide;Anisole, p-bromo-
    CAS: 104-92-7
    MF: C7H7BrO
    MW: 187.03
    EINECS: 203-252-1
    Product Categories: Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;alkyl bromide;Anisole;AnisoleSeries;Aromatic Ethers
    Mol File: 104-92-7.mol
    Shop 4-Bromoanisole CAS:104-92-7-Detailed Image 1

    4-Bromoanisole Chemical Properties
    Melting point  9-10 °C (lit.)
    Boiling point  223 °C (lit.)
    density  1.494 g/mL at 25 °C (lit.)
    refractive index  n20/D 1.564(lit.)
    Fp  202 °F
    storage temp.  Store below +30°C.
    solubility  Chloroform (Sparingly), Ethyl Acetate (Slightly)
    form  Liquid
    color  Clear colorless to slightly yellow
    Water Solubility  immiscible
    Merck  14,1428
    BRN  1237590
    Dielectric constant 7.4000000000000004
    Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
    InChIKey QJPJQTDYNZXKQF-UHFFFAOYSA-N
    CAS DataBase Reference 104-92-7(CAS DataBase Reference)
    NIST Chemistry Reference Benzene, 1-bromo-4-methoxy-(104-92-7)
    EPA Substance Registry System Benzene, 1-bromo-4-methoxy- (104-92-7)

    Safety Information
    Hazard Codes  Xn
    Safety Statements  23-24/25
    WGK Germany  2
    RTECS  BZ8501000
    8
    TSCA  Yes
    HS Code  29093038
    Toxicity LD50 orl-mus: 2200 mg/kg GISAAA 44(12),19,79


    4-Bromoanisole Usage And Synthesis
    Chemical Properties 4-Bromoanisole is a colourless to pale yellow oily liquid with a pleasant smell similar to that of anise seed. Insoluble in water, soluble in ethanol, ether and chloroform. It is one of three isomers of bromoanisole, the others being 3-bromoanisole and 2-bromoanisole. It is the precursor to many 4-anisyl derivatives.
    Uses 4-Bromoanisole finds application as an intermediate in synthetic chemistry. It is used in the preparation of aryl 1,3-diketones and ethyl 4-methoxycinnamate. It is a used as a brominating reagent. Further, it is used in Suzuki coupling reaction with phenylboronic acid as well as in Heck reaction.
    Preparation 4-Bromoanisole is obtained by reacting p-bromophenol with dimethyl sulfate.
    Definition ChEBI: 4-bromoanisole is a monomethoxybenzene carrying a bromo substituent at position 4. It is a monomethoxybenzene and an organobromine compound.
    Biological Functions 4-Bromoanisole is compound sometimes used in RNA extraction which serves to further eliminate DNA contamination. It interacts with genomic DNA(gDNA) and through a separation phase, it will be located in the organic layer instead of the aqueous layer (upper layer) containing the RNA extract.
    Synthesis Reference(s) Tetrahedron Letters, 35, p. 7429, 1994 DOI: 10.1016/0040-4039(94)85333-9
    Synthesis, p. 868, 1986 DOI: 10.1055/s-1986-31813
    General Description 4-Bromoanisole is a useful brominating reagent. It is formed as reaction product in the reaction between HOBr and anisole. Suzuki coupling of 4-bromoanisole with phenylboronic acid catalyzed by palladium pincer complexes has been studied. Heck Reaction of 4-bromoanisole with ethyl acrylates in room-temperature ionic liquids is reported to afford ethyl 4-methoxycinnamate.
    Safety Profile Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic vapors of Br-.
    Purification Methods Crystallise the anisole by repeated partial freezing, then distil it under reduced pressure. [Beilstein 6 III 741, 6 IV 1044.]

    Shop Orthophosphorus acid 10294-56-1-Detailed Image 1

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    ——  Q&A  ——

    Q1:Do you provide sample?

    A: Yes, we can provide free sample, you only need pay the shipping cost.

    Q2: What is the lead time?

    A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

    Q3: How can I buy? What is the payment method?

    A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer, 

    Q4:What if there are quality issues?

    A:We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.



    Certificates

    Basic Info
    Product Name:

    4-Bromoanisole

    Other Name:

    Benzene,1-bromo-4-methoxy-;Anisole,p-bromo-;1-Bromo-4-methoxybenzene;p-Bromoanisole;4-Bromoanisole;p-Bromanisole;p-Bromophenyl methyl ether;4-Methoxy-1-bromobenzene;p-Methoxyphenyl bromide;p-Methoxybromobenzene;4-Methoxybromobenzene;4-Anisyl bromide;4-Methoxyphenyl bromide;p-Anisyl bromide;4-Bromomethoxybenzene;p-Bromomethoxybenzene;4-Bromo-1-methoxybenzene;1-Methoxy-4-bromobenzene;NSC 8042;4-Bromoanisol

    CAS No.:

    104-92-7

    Molecular Formula:

    C7H7BrO

    InChIKeys:

    InChIKey=QJPJQTDYNZXKQF-UHFFFAOYSA-N

    Molecular Weight:

    187.036

    Exact Mass:

    187.03

    EC Number:

    203-252-1

    UNII:

    U430F901J9

    NSC Number:

    8042

    DSSTox ID:

    DTXSID2059308

    HScode:

    29093038

    Characteristics
    PSA:

    9.2

    XLogP3:

    3.16

    Density:

    1.494 g/mL at 25 °C(lit.)

    Melting Point:

    13.5 °C

    Boiling Point:

    215 °C

    Flash Point:

    202 °F

    Refractive Index:

    n 20/D 1.564(lit.)

    Water Solubility:

    immiscible

    Vapor Pressure:

    0.20 mmHg

    Toxicity:

    LD50 orl-mus: 2200 mg/kg GISAAA 44(12),19,79

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H315 Causes skin irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    4-Bromoanisole (1-Bromo-4-methoxybenzene)

    250 KG Jan 21, 2026
    Brazil

    4-Bromoanisole

    30 MT Nov 15, 2024
    India

    Para Bromo Anisole

    1.00 MT Oct 23, 2023
    Post an enquiry for this product
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