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1-Bromo-3-chloropropane 109-70-6

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Unit Price: Get Latest Price
CAS No.:

109-70-6

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2025-12-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    1-Bromo-3-chloropropane Chemical Properties
    Melting point  -59 °C
    Boiling point  144-145 °C (lit.)
    density  1.592 g/mL at 25 °C (lit.)
    vapor pressure  7.5 hPa (20 °C)
    refractive index  n20/D 1.486(lit.)
    Fp  81 °C
    storage temp.  room temp
    solubility  2.24g/l insoluble
    form  liquid
    color  Clear liquid
    explosive limit 3.2-8.6%(V)
    Water Solubility  insoluble
    BRN  605278
    Stability: Volatile
    CAS DataBase Reference 109-70-6(CAS DataBase Reference)
    IARC 2B (Vol. 125)
    NIST Chemistry Reference Propane, 1-bromo-3-chloro-(109-70-6)
    EPA Substance Registry System Propane, 1-bromo-3-chloro- (109-70-6)


    1-Bromo-3-chloropropane Usage And Synthesis
    Description 1-Bromo-3-chloropropane is a halogenated alkane compound containing one bromine atom and one chlorine atom in its structure. Due to the high electronegativity of halogens, the molecule of 1-Bromo-3-chloropropane is highly electrophilic and is easily attacked by electrophilic reagents such as nucleophilic reagents, Lewis acid, etc., which undergoes nucleophilic substitution reactions. The compound is relatively stable at room temperature, but is susceptible to elimination reactions at high temperatures or in the presence of strong acids or bases. In addition, prolonged exposure to air should be avoided because 1-Bromo-3-chloropropane molecules contain halogen atoms that are susceptible to reaction by oxygen and moisture in the air to produce products such as alcohols and aldehydes.
    Chemical Properties It is a clear and colorless liquid that is soluble in ethanol, ether, and chloroform but insoluble in water.
    Uses 1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
    Preparation The most common method for producing 1-Bromo-3-chloropropane is through the free-radical addition of anhydrous hydrogen bromide to allyl chloride. Alternatively, it can be prepared by reacting ethylene with methylene chlorobromide.
    Definition ChEBI: 1-Bromo-3-chloropropane (I-BCP or 109-70-6) is an organochlorine compound that can be used as a safer and equally effective alternative to chloroform. It serves as a phase-separation agent for the one-step method of RNA isolation from biological samples like animal and plant tissue. I-BCP can replace CHCl3 in RNA phase separations.
    General Description 1-bromo-3-chloropropane appears as a colorless liquid. Insoluble in water and denser than water. May be toxic by inhalation, ingestion or skin absorption. Used to make pharmaceuticals and other chemicals.
    Air & Water Reactions Insoluble in water.
    Reactivity Profile Halogenated aliphatic compounds, such as 1-Bromo-3-chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

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    ——  Q&A  ——

    Q1:Do you provide sample?

    A: Yes, we can provide free sample, you only need pay the shipping cost.

    Q2: What is the lead time?

    A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

    Q3: How can I buy? What is the payment method?

    A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer, 

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    Certificates

    Basic Info
    Product Name:

    1-Bromo-3-chloropropane

    Other Name:

    Propane,1-bromo-3-chloro-;1-Bromo-3-chloropropane;Trimethylene bromide chloride;Trimethylene chlorobromide;1-Chloro-3-bromopropane;3-Chloro-1-bromopropane;3-Bromopropyl chloride;3-Bromo-1-chloropropane;3-Chloropropyl bromide;ω-Chlorobromopropane;NSC 9183;3-Chloropropan-1-yl bromide

    CAS No.:

    109-70-6

    Molecular Formula:

    C3H6BrCl

    InChIKeys:

    InChIKey=MFESCIUQSIBMSM-UHFFFAOYSA-N

    Molecular Weight:

    157.44

    Exact Mass:

    157.44

    BRN:

    605278

    EC Number:

    203-697-1

    UNII:

    KA4WR2LS00

    ICSC Number:

    1665

    NSC Number:

    9183

    UN Number:

    2688

    DSSTox ID:

    DTXSID1051565

    Color/Form:

    COLORLESS LIQUID

    HScode:

    29034980

    Characteristics
    PSA:

    0

    XLogP3:

    2.18

    Appearance:

    1-bromo-3-chloropropane appears as a colorless liquid. Insoluble in water and denser than water. May be toxic by inhalation, ingestion or skin absorption. Used to make pharmaceuticals and other chemicals.

    Density:

    1.5969 g/cm3 @ Temp: 20 °C

    Melting Point:

    -58.90 °C

    Boiling Point:

    143.3 °C @ Press: 760 Torr

    Flash Point:

    81 °C

    Refractive Index:

    n 20/D 1.486(lit.)

    Water Solubility:

    H2O: insoluble

    Storage Conditions:

    room temp

    Vapor Pressure:

    Vapour pressure, kPa at 25°C: 0.85

    Vapor Density:

    Relative vapour density (air = 1): 5.4

    Toxicity:

    Oral-Rat  LD50: 930 mg/kg; Oral-Mouse LD50:1290 mg/kg

    Flammability characteristics:

    Open flame is flammable; reacts with oxidant; decomposes with high heat and emits toxic chlorine and bromide gas in case of acid

    Explosive limit:

    3.2-8.6%(V)

    Experimental Properties:

    LB/GAL: 13.27 @ 25 °C

    Air and Water Reactions:

    Insoluble in water.

    Reactive Group:

    Halogenated Organic Compounds

    Reactivity Profile:

    Halogenated aliphatic compounds, such as 1-BROMO-3-CHLOROPROPANE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Acute toxicity - Category 3, Inhalation

    Specific target organ toxicity – single exposure, Category 3

    Germ cell mutagenicity, Category 2

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H331 Toxic if inhaled

    H335 May cause respiratory irritation

    H341 Suspected of causing genetic defects

    H412 Harmful to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames, NO sparks and NO smoking. Above 57°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    1-Bromo-3-Chloropropane

    40 MT Sep 4, 2025
    Post an enquiry for this product
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