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4'-Methylpropiophenone CAS:5337-93-9 C10H12O

Name: 4'-Methylpropiophenone CAS:5337-93-9 C10H12O
Brand: Orient
SKU: pr2512241129
Price: 4 USD
Availability: InStock

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CAS No.:

5337-93-9

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2026-01-24

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	4'-Methylpropiophenone
Synonyms:	ETHYL-P-TOLYLKETON;LABOTEST-BB LT00053050;P-TOLYL ETHYL KETONE;P-METHYLPROPIOPHENONE;4-METHYLPROPIOPHENONE;P-Methyl phenylethylketone;1-(4-methylphenyl)-propan-1-one;Ethylp-tolylketone
CAS:	5337-93-9
MF:	C10H12O
MW:	148.2
EINECS:	226-267-5
Product Categories:	C10;Carbonyl Compounds;Aromatic Propiophenones (substituted);Ketones;Carbonyl Compounds;Intermediate;5337-93-9;ADVANCED INT.
Mol File:	5337-93-9.mol

4'-Methylpropiophenone Chemical Properties

Melting point	7.2 °C
Boiling point	238-239 °C(lit.)
density	0.993 g/mL at 25 °C(lit.)
refractive index	n20/D 1.528(lit.)
Fp	229 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in chloroform and hexane.
form	Oil
Specific Gravity	0.99
color	Colourless
BRN	2042137
InChI	InChI=1S/C10H12O/c1-3-10(11)9-6-4-8(2)5-7-9/h4-7H,3H2,1-2H3
InChIKey	PATYHUUYADUHQS-UHFFFAOYSA-N
SMILES	C(C1=CC=C(C)C=C1)(=O)CC
CAS DataBase Reference	5337-93-9(CAS DataBase Reference)
NIST Chemistry Reference	4'-Methylpropiophenone(5337-93-9)

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29143990

MSDS Information

4'-Methylpropiophenone Usage And Synthesis

Chemical Properties	clear light yellow liquid
Uses	4'-methylpropiophenone has been reported to be used in the synthesis of pharmaceutical compounds such as tolperisone and other muscle relaxants. The substance is also a starting material in the synthesis of 4-methylmethcathinone (mephedrone). Mephedrone has been encountered as a ‘legal high’ and on the illicit drug market masquerading as cocaine (in powder form), MDMA (in tablet form) and as an adulterant. According to the 2016 European Drugs Market Report produced by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), mephedrone has created a specific demand and carved its own distinct market share.
Uses	4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions.
Application	4′-Methylpropiophenone can be used as a building block to synthesize: N-(4-Chlorophenyl)-N′-[1-(4-methylphenyl)propyl]urea as a potential CRAC channel inhibitor. Mono and trinuclear cobaloxime/organocobaloxime complexes, which are used as efficient catalysts for the synthesis of cyclic carbonates. Tolperisone (TOL) via acid-catalyzed reaction with piperidine hydrochloride and 1,2-dioxolane.
Definition	ChEBI: 4-methylpropiophenone is an aromatic ketone that is propiophenone bearing a methyl group at C-4. It derives from a propiophenone.
Synthesis	4'-Methylpropiophenone can be synthesized through various methods. One common approach involves the reaction of propiophenone with methylmagnesium bromide or methyl lithium in the presence of a catalyst. Another method utilizes Friedel-Crafts acylation, where propiophenone is acylated with methyl chloride or methyl bromide using a Lewis acid catalyst. These methods allow for the controlled introduction of the methyl group onto the phenyl ring.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

4′-Methylpropiophenone

Other Name:

1-Propanone,1-(4-methylphenyl)-;Propiophenone,4′-methyl-;1-(4-Methylphenyl)-1-propanone;4′-Methylpropiophenone;p-Methylpropiophenone;Ethyl p-tolyl ketone;Ethyl 4-methylphenyl ketone;1-(4-Tolyl)-1-propanone;NSC 852;1-p-Tolylpropan-1-one

CAS No.:

5337-93-9

Molecular Formula:

C10H12O

InChIKeys:

InChIKey=PATYHUUYADUHQS-UHFFFAOYSA-N

Molecular Weight:

148.2

Exact Mass:

148.20

BRN:

2042137

EC Number:

226-267-5

UNII:

8490C17WAB

NSC Number:

852

DSSTox ID:

DTXSID00201535

HScode:

2914399090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

17.1

XLogP3:

2.6

Appearance:

Light yellow liquid.

Density:

0.9883 g/cm³ @ Temp: 21.7 °C

Melting Point:

7.2 °C

Boiling Point:

236 °C

Flash Point:

229 °F

Refractive Index:

1.507

Water Solubility:

soluble in chloroform and hexane.

Storage Conditions:

Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.

Vapor Pressure:

0.09 mmHg

See More 4′-Methylpropiophenone Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Sub-category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H401 Toxic to aquatic life
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 4′-Methylpropiophenone Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

8 Inquiries

Country	Product	Purchase Quantity	Date Posted
China	5337-93-9	0.5 MT	Sep 24, 2024
India	4'-Methylpropiophenone	10 L	Dec 19, 2025
United States	4′-Methylpropiophenone	2 MT	Mar 5, 2025
Kazakstan	4-Methylpropiophenone	25 KG	Sep 13, 2024
Austria	4-Methylpropiophenone	1 TON	Jan 25, 2024
India	4'-Methylpropiophenone	10 KG	Jan 2, 2026
India	4 methylepropiopbenon	200 KG	Oct 5, 2025
Denmark	2-Phenethyl bromide	100 KG	Jun 23, 2025

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