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2-Hydroxyethylhydrazine CAS:109-84-2

Name: 2-Hydroxyethylhydrazine CAS:109-84-2
Brand: Orient
SKU: pr2512263175
Price: 4 USD
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CAS No.:

109-84-2

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2026-01-26

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	2-Hydroxyethylhydrazine
Synonyms:	1-(2-Hydroxyethyl)hydrazine;2-Hydrazineethanol;BETA-HYDROXYETHYL HYDRAZINE;ETHANOL-2-HYDRAZINE;HYDROXYETHYL HYDRAZINE;(2-Hydroxyethyl)drazine;2-Hydroxyethylhydrazine,97%;2-HYDROXYETHYLHYDRAZINE, TECH., 90%
CAS:	109-84-2
MF:	C2H8N2O
MW:	76.1
EINECS:	203-711-6
Product Categories:	Pharmaceutical Intermediate;pharmacetical;Aliphatics
Mol File:	109-84-2.mol

2-Hydroxyethylhydrazine Chemical Properties

Melting point	−70 °C(lit.)
Boiling point	155-160 °C32 mm Hg(lit.)
density	1.123 g/mL at 25 °C(lit.)
refractive index	n20/D 1.493(lit.)
Fp	165 °F
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	soluble in DMSO, Methanol
pka	14.79±0.10(Predicted)
form	Liquid
color	Colorless to Almost colorless
Water Solubility	Soluble in water, alcohols and glycols.
Merck	13,4794
BRN	1731669
InChIKey	GBHCABUWWQUMAJ-UHFFFAOYSA-N
CAS DataBase Reference	109-84-2(CAS DataBase Reference)
NIST Chemistry Reference	2-Hydroxyethylhydrazine(109-84-2)
EPA Substance Registry System	2-Hydroxyethylhydrazine (109-84-2)

Safety Information

Hazard Codes	T
Risk Statements	23/24/25-36/37/38-40-25
Safety Statements	23-26-36/37/39-45-60-20
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
RTECS	KL2800000
Hazard Note	Toxic
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29280000

MSDS Information

2-Hydroxyethylhydrazine Usage And Synthesis

Description	2-Hydroxyethylhydrazine (HEH) is the primary decomposition product of the high-energy ionic liquid 2-hydroxyethylhydrazinium nitrate (HEHN). As a hydrazine fuel, HEHN is the most widely used liquid monocomponent propellant in the aerospace sector. while HEH is a key target for investigating the reaction mechanism of HEHN.
Chemical Properties	Clear colorless oily liquid
Uses	2-Hydroxyethylhydrazine is used as an intermediate, plant growth regulator, flowering inducer for pineapples.
Uses	(2-Hydroxyethyl)hydrazine is used as a plant growth regulant, a component in jet fuels, intermediate for organic synthesis especially heterocycles used in agrochemicals, pharmaceuticals, stabilizers and polymerizations, Chain extender for urethane formulations, corrosion inhibitor.
Definition	ChEBI: 2-hydrazinoethanol is a member of hydrazines. It has a role as a herbicide. It is functionally related to an ethanol.
Preparation	2-Hydroxyethylhydrazine is prepared by heating about 2 to 17 parts of hydrazine hydrate dissolved in water to about 30℃ to about 100℃. in a closed system. Then, 1 part of ethylene oxide is gradually added to the hydrazine hydrate, and the temperature of the reaction mixture is maintained in the range of about 30℃ to 70℃ during the addition.
General Description	2-Hydroxyethylhydrazine reacts with β-diketones having strong electron-withdrawing substituents to yield 5-hydroxy-4,5-dihydropyrazoles.
Hazard	Moderate fire risk. Irritant.
Biological Activity	2-Hydroxyethylhydrazine (HEH) is a potent and highly specific inhibitor of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae. Following HEH addition to culture medium, the incorporation of L-[3-¹⁴C]serine, L-[methyl-¹⁴C]methionine, and S-adenosyl-L-[methyl-¹⁴C]methionine into phosphatidylcholine was markedly reduced. In the presence of this inhibitor, cells ceased growth with an IC50 value of 66 pM. Although cellular activity remained unaffected, the addition of choline restored cell growth. This indicates that active phospholipid methylation is unnecessary as long as phosphatidylcholine is supplied via the CDP-choline pathway. The restoration of cell growth by choline suggests that HEH's primary target in vivo is phospholipid methylation.
Synthesis	75-21-8 109-84-2 The general procedure for synthesizing 2-hydrazinoethanol from ethylene oxide was as follows: ethylene oxide was added to a VO1 liquefied gas storage tank and pressurized to 1.0~1.5 MPa using nitrogen. 80% hydrazine hydrate was added to a VO2 storage tank, and the molar ratio of hydrazine hydrate to ethylene oxide was controlled to be 8:1. the hydrazine hydrate was fed at a total feed flow rate of 2.0 L/h via feed pumps PO1 and PO2, respectively. The temperature of the micro-mixer was maintained at 40°C, the temperature of the cracking reactor was set at 60°C, the temperature of the micro-heat exchanger was controlled in the range of 0-10°C, and the back pressure of the back-pressure valve was set at 1.5-2.5 MPa. The two liquid feedstocks were mixed in a CPMM-R300 micro-mixer and then entered into the cracking reactor for further reaction. The reaction liquid is cooled by a micro heat exchanger and then micro-fed to the receiving vessel. Most of the water and excess hydrazine hydrate were removed by decompression distillation, and the final colorless oily liquid 2-hydroxyethylhydrazine was obtained. The purity of the product was 89.5% and the yield was 98% by GC. Finally, the entire microreactor system was washed using water.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Hydroxyethylhydrazine

Other Name:

Ethanol,2-hydrazinyl-;Ethanol,2-hydrazino-;2-Hydrazinylethanol;BOH;HEH;(β-Hydroxyethyl)hydrazine;2-Hydrazineethanol;(2-Hydroxyethyl)hydrazine;Ethanolhydrazine;1-(2-Hydroxyethyl)hydrazine;2-Hydrazinoethanol;2-Hydrazinoethyl alcohol;N-(2-Hydroxyethyl)hydrazine;Hydroxyethylhydrazine;Hydrazineethanol;NSC 189820;2-Hydrazinylethan-1-ol;856640-34-1

CAS No.:

109-84-2

Molecular Formula:

C2H8N2O

InChIKeys:

InChIKey=GBHCABUWWQUMAJ-UHFFFAOYSA-N

Molecular Weight:

76.1

Exact Mass:

76.10

EC Number:

203-711-6

UNII:

8T2Z8Z231F

NSC Number:

189820

DSSTox ID:

DTXSID1020728

HScode:

29280000

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

58.3

XLogP3:

-1.6

Appearance:

Liquid

Density:

1.123 g/cm³ @ Temp: 23 °C

Melting Point:

-70 °C

Boiling Point:

219 °C

Flash Point:

165 °F

Refractive Index:

n 20/D 1.493(lit.)

Water Solubility:

soluble in water,alcohols and glycols.

Storage Conditions:

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Vapor Pressure:

0.015mmHg at 25°C

See More Hydroxyethylhydrazine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Dermal

Skin irritation, Category 2

Eye irritation, Category 2

Acute toxicity - Category 3, Inhalation

Specific target organ toxicity â single exposure, Category 3

Carcinogenicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H311 Toxic in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H331 Toxic if inhaled H335 May cause respiratory irritation H351 Suspected of causing cancer
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Hydroxyethylhydrazine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Japan	2-Hydroxyethylhydrazine	2 TON	Apr 22, 2025

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