Industrial Grade 99.5% Dimethyl Sulphate CAS 77-78-1 Methylating Agent for Organic Synthesis

Dimethyl Sulphate (DMS, Sulfuric Acid Dimethyl Ester, CAS:77-78-1,EINECS:201-058-1, HS Code:29209010, molecular formula (CH₃)₂SO₄, MW:126.13) is a colorless transparent oily liquid with a faint onion-like odor, produced via advanced continuous esterification process of dimethyl ether with sulfur trioxide followed by vacuum distillation purification. Our industrial grade DMS features ≥99.5% minimum purity with strictly controlled acidity and moisture content, complying with HG/T 4001-2008 and international industrial standards. As the most efficient and cost-effective methylating agent in organic chemistry, it readily transfers methyl groups to various nucleophiles under mild conditions, enabling the synthesis of thousands of downstream chemicals. It is slightly soluble in cold water but hydrolyzes rapidly in hot water or alkaline solutions to form sulfuric acid and methanol.

Organic Synthesis & Chemical Manufacturing (Core Application)
Universal methylating agent for introducing methyl groups into alcohols, phenols, amines and carboxylic acids
Primary raw material for producing dimethyl sulfoxide (DMSO), caffeine, theophylline and vanillin
Intermediate for synthesizing surfactants, plasticizers and rubber chemicals
Pharmaceutical Industry
Key reagent for manufacturing analgesics (aminopyrine, analgin), antibiotics and cardiovascular drugs
Used in producing antimalarials, antihistamines and central nervous system medications
Pesticide Industry
Intermediate for synthesizing insecticides (acephate), fungicides (dimethomorph) and herbicides
Enables the construction of active molecular structures in modern agrochemicals
Dye & Fragrance Industry
Methylating agent for producing cationic dyes, azo dyes and optical brighteners
Used in synthesizing various synthetic fragrances and flavor compounds

Product Advantages
✅ 99.5% ultra-high purity with minimal impurities, ensuring high reaction yield and product quality
✅ Low acidity profile preventing equipment corrosion and side reactions during synthesis
✅ Excellent methylating efficiency requiring lower dosage compared to alternative methylating agents
✅ Stable chemical properties under normal storage and transportation conditions
✅ Strict batch-by-batch quality control with complete COA and regulatory documentation
✅ Large-scale production capacity with stable supply to support long-term bulk orders
✅ Comprehensive safety support including detailed MSDS and emergency response guidance

Packaging & Storage
Standard packaging: 250kg UN certified steel drums with nitrogen sealing; ISO tank containers available for bulk orders. Store in a cool, dry, well-ventilated Class 6.1 toxic substance warehouse with explosion-proof lighting and ventilation systems. Keep containers tightly sealed to prevent leakage and moisture absorption. Strictly isolate from strong alkalis, ammonia, oxidizing agents and food/feed products. Store in an area without drain or sewer access to prevent environmental contamination. Shelf life is 12 months under proper storage conditions.

1. 1.A 70,000 ㎡ warehouse (20,000 MT capacity) with moisture-proof and temperature-controlled systems, enabling efficient fulfillment of large-volume orders.
2. 2.Free samples (Ship within 3-7 days) to let you test products at zero trial cost.
3. 3.Transparent lead time for hazardous chemicals: 45–60 days, with clear delivery schedules.
4. 4.Certified with a Hazardous Chemical Business License and ISO certification, ensuring smooth customs clearance.
5. 5.6 packaging options with customizable logos to minimize product loss during transportation.
6. 6.Over 400 chemical SKUs available for one-stop procurement, helping you reduce sourcing costs.