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3-AMinopyridine462-08-8

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$33-34/MT FOB

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CAS No.:

462-08-8

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

上海

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Price valid (until):

2026-07-18

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

3-Aminopyridine Basic information

Product Name:	3-Aminopyridine
Synonyms:	3-amino-pyridin;3-Aminopyridine ,98%;3-mydroxypiperidine;3-aMatopyridate;NSC 15040;Pyridine, 3-aMino- (8CI);AMINOPYRIDINE, 3-(RG);462-08-0
CAS:	462-08-8
MF:	C5H6N2
MW:	94.11
EINECS:	207-322-2
Product Categories:	Building Blocks;C5;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines;Pharmaceutical intermediates;FINE Chemical & INTERMEDIATES;Pyridine;Organics;Pyridine series;Pyridines derivates
Mol File:	462-08-8.mol

3-Aminopyridine Chemical Properties

Melting point	60-63 °C(lit.)
Boiling point	248 °C(lit.)
density	1.0308 (estimate)
refractive index	1.5560 (estimate)
Fp	124 °C
storage temp.	Poison room
solubility	>1000g/l
pka	6.04(at 25℃)
form	Liquid
color	Clear colorless to yellow
PH	10 (100g/l, H2O, 20℃)
Water Solubility	It is soluble in water as well as soluble in alcohol, benzene.
Sensitive	Air Sensitive & Hygroscopic
Merck	14,473
BRN	105692
InChI	1S/C5H6N2/c6-5-2-1-3-7-4-5/h1-4H,6H2
InChIKey	CUYKNJBYIJFRCU-UHFFFAOYSA-N
SMILES	Nc1cccnc1
LogP	0.110
CAS DataBase Reference	462-08-8(CAS DataBase Reference)
NIST Chemistry Reference	3-Pyridinamine(462-08-8)
EPA Substance Registry System	3-Aminopyridine (462-08-8)

Safety Information

Hazard Codes	T,Xi
Risk Statements	23/24/25-33-36/37/38-25
Safety Statements	36/37/39-45-37/39-28B-26
RIDADR	UN 2671 (AMINOPYRIDINES (o-, m-, p,))
WGK Germany	3
RTECS	US1650000
F	3-8-9-23
Hazard Note	Toxic/Irritant
TSCA	TSCA listed
HazardClass	6.1
PackingGroup	II
HS Code	29333999
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT RE 2 STOT SE 3
Toxicity	LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65

MSDS Information

Provider	Language
3-Pyridinamine	English
ACROS	English
SigmaAldrich	English
ALFA	English

3-Aminopyridine Usage And Synthesis

Chemical Properties	white to light yellow crystal powder
Uses	3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,
Uses	manufacture of pharmaceuticals and dyes.
Uses	3-Aminopyrodine is also used as an intermediate for agrochemicals, pharmaceuticals and colorants. These are involved in photosensitizer chemistry, luminescent materials, metal complex chemistry and liquid crystal. Aminopyridine is used as a monomer for polymerization. It is also used in the Production of cationic dyes and Apa amoxicillin sodium raw materials.
Synthesis Reference(s)	Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2 The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047
Safety Profile	Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,.
Purification Methods	It crystallises from benzene, CHCl3/pet ether (b 60-70o), or benzene/pet ether (4:1). [Beilstein 22/9 V 3.]

3-Aminopyridine Preparation Products And Raw materials

Raw materials	Potassium hydroxide-->tert-Butanol-->Aluminum oxide-->Nicotinamide-->Lead tetraacetate-->3-Piperidinamine, 6-chloro--->Sulfuric acid-->2-Chloro-5-nitropyridine-->5-Amino-2-chloropyridine-->5-Amino-2-bromopyridine
Preparation Products	3-IODO-2-NITROPYRIDINE-->6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE-->N-(4-FORMYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE-->TERT-BUTYL 4-FORMYLPYRIDIN-3-YLCARBAMATE-->Pirenzepine-->2,6-Dichloropyridin-3-amine-->3-HYDRAZINOPYRIDINE Dihydrochloride-->3-Iodopyridine-->2,6-Dibromopyridin-3-amine-->1,5-NAPHTHYRIDINE-2-CARBOXYLICACID -->2-Chloro-3-fluoropyridine-->2,6-Dibromopyridine

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Basic Info

Product Name:

3-Aminopyridine

Other Name:

3-Pyridinamine;Pyridine,3-amino-;3-Aminopyridine;β-Aminopyridine;3-Pyridylamine;m-Aminopyridine;3-Pyridinylamine;NSC 15040;2376813-18-0

CAS No.:

462-08-8

Molecular Formula:

C5H6N2

InChIKeys:

InChIKey=CUYKNJBYIJFRCU-UHFFFAOYSA-N

Molecular Weight:

94.11

Exact Mass:

94.11

BRN:

105692

EC Number:

207-322-2

UNII:

69JE8P2L84

NSC Number:

15040

DSSTox ID:

DTXSID9047461

HScode:

2933399090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

38.9

XLogP3:

-0.02

Appearance:

Clear colorless to yellow Liquid

Density:

1.1±0.1 g/cm3

Melting Point:

64.5 °C

Boiling Point:

252 °C

Flash Point:

124 °C

Refractive Index:

1.588

Water Solubility:

It is soluble in water as well as soluble in alcohol, benzene.

Storage Conditions:

Poison room

Vapor Pressure:

0.021mmHg at 25°C

Toxicity:

Peritoneal-mouse LD50: 28 mg/kg; subcutaneous-mouse LD50: 30 mg/kg

Flammability characteristics:

Open flame is flammable; heated to decompose toxic nitrogen oxide gas

See More 3-Aminopyridine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Dermal

Skin irritation, Category 2

Eye irritation, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H311 Toxic in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 3-Aminopyridine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	2 AMINO PYRIDINE	5000.00 KG	Oct 10, 2024
India	2 HYDROXY 1,4 NAPTHOQUINONE	4000.00 KG	Oct 10, 2024
India	STEARYL ISOCYANATE	500.00 KG	Oct 10, 2024

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