 Home > Encyclopedia > 2-Amino-3-bromopyridine

2-Amino-3-bromopyridine

2-Amino-3-bromopyridine structure

CAS No:
13534-99-1
Formula:
C5H5BrN2
Chemical Name:
2-Amino-3-bromopyridine
Synonyms:
2-Pyridinamine,3-bromo-;Pyridine,2-amino-3-bromo-;3-Bromo-2-pyridinamine;3-Bromo-2-aminopyridine;2-Amino-3-bromopyridine;(3-Bromopyridin-2-yl)amine;2-Amino-3-bromo-2-pyridine
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Request for Quotation

Description

grey to brown powder

2-Amino-3-bromopyridine Basic Attributes

Molecular Weight：

173.01

Exact Mass：

173.01

BRN：

109867

EC Number：

-0

DSSTox ID：

DTXSID00355840

HScode：

29333990

Characteristics

PSA：

38.9

XLogP3：

1.2

Appearance：

Gray to brown Powder

Density：

1.6065 (rough estimate)

Melting Point：

65-66 °C

Boiling Point：

232.0±20.0 °C(Predicted)

Flash Point：

94.1±21.8 °C

Refractive Index：

1.5182 (estimate)

Vapor Pressure：

0.0604mmHg at 25°C

Safety Information

Packing level：

Hazard category：

IRRITANT

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H302 (12.77%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 47 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Amino-3-bromopyridine Use and Manufacturing

30 g of 3-bromo-5-iodopyridin-2-amine and 300 ml of ethanol were added1 g palladium / silica, First replace the air with nitrogen three times, And then replaced with hydrogen three times.Adjust the pressure of 0.05Mpa ~ 0.1Mpa, Temperature control at 20 ~ 30 , until the raw material reaction is complete.Filtration recovery catalyst, Concentrated part of the solvent, Add 300 ml of water, Then add 4.2 g of sodium hydroxide to neutralize, Cooled to 0 ~ 5 , filtered and dried.To give 16.8 g of 3-bromopyridin-2-amine, Yield 97percent.To a stirred solution of N-(3-Bromo-pyridin-2-yl)-2, 2-dimethyl-propionamide

Computed Properties

Molecular Weight:173.01
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:171.96361
Monoisotopic Mass:171.96361
Topological Polar Surface Area:38.9
Heavy Atom Count:8
Complexity:76.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2-Amino-3-bromopyridine

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

3-Bromo-2-pyridinamine 99%

CAS No.: 13534-99-1

Content: 99%

Inquiry
Shaanxi Cuikang Pharmaceutical Technolog Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials,Fine Chemicals,Synthetic customization

3-Bromo-2-pyridinamine

CAS No.: 13534-99-1

Grade: Industrial Grade

Content: 99%

Inquiry