DSE

256.34

255.920914

205-547-0

0L6N5662WT

3077|2588

DTXSID5020603

Colorless crystals when pure.|Crystals from water

29302000

138.84000

1.91220

Nabam is a colorless to light amber solid with a a slight odor. Mixes with water. (USCG, 1999)

1.342 g/mL at 25 °C(lit.)

76-80 °C

308.2ºC at 760 mmHg

140.2ºC

n20/D 1.532(lit.)

ca. 200 g l -1 (room temperature)Water soluble . Decomposes in boiling hot to give poisonous hydrogen sulfide and flammable carbon disulfide.

0-6°C

Negligible

Oral-rat LD50: 395 mg/kg; Oral-Mouse LD50:380 mg/kg

Thermal decomposition of toxic nitrogen oxide and sulfur oxide gases

Henry's Law constant = 1.6X10-18 atm-cu m/mol at 25 °C (est)

Crystals from alcohol. Moderately soluble in water. Forms a continuous film on plant surfaces, which is said to become insoluble in water. /Nabam hexahydrate/|Colorless crystals /Hexahydrate/|NABAM FORMS ETHYLENETHIURAM DISULFIDE AND ETHYLENETHIURAM MONOSULFIDE, WHICH IS READILY CONVERTED TO AN ISOTHIOCYANATE; NABAM CAN ALSO BE CONVERTED UNDER MILDLY ACID CONDITIONS TO ETHYLENETHIOUREA AND HYDROGEN SULFIDE, AND UNDER MORE DRASTIC CONDITIONS TO ETHYLENEDIAMINE & CS2|Hydroxyl radical reaction rate constant = 1.47X10-10 cu cm/molec-sec at 25 °C (est)

Water soluble. Decomposes in boiling hot to give poisonous hydrogen sulfide and flammable carbon disulfide.

Thiocarbamate Esters and Salts/Dithiocarbamate Esters and Salts

NABAM is a dithiocarbamate. Flammable gases are generated by the combination of thiocarbamates and dithiocarbamates with aldehydes, nitrides, and hydrides. Thiocarbamates and dithiocarbamates are incompatible with acids, peroxides, and acid halides.

Aqueous soln is corrosive

II

8

UN30779/PG3

3

36/37/38-50/53-43-37-22

26-36/37/39-61-60-46-24/25-8

FA6825000

Xn,N

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Unstable in dry, crystalline form

P261-P273-P280-P501

H302-H317-H335-H410

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U114, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.|A potential candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds. A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A potential candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids. /Ethylenebisdithiocarbamate/|Do not discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans or other waters unless in accordance with the requirements of a National Pollutant Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge. ... For guidance contact your State Water Board or Regional Office of the EPA.

WHO; Environmental Health Criteria 78: Dithiocarbamate Pesticides, ethylenethiourea and Propylenethiourea (1988). EHC are designed for scientists and administrators responsible for the establishment of safety standards and regulations and provide basic scientific risk evaluations of a wide range of chemicals and groups of chemicals.[Available from, as of March 4, 2010: http://www.inchem.org/pages/ehc.html]|USEPA/OPP; Reregistration Eligibility Decision Document - Nabam EPA-738-R-95-035 (January 1996). The RED summarizes the risk assessment conclusions and outlines any risk reduction measures necessary for the pesticide to continue to be registered in the U.S.[Available from, as of March 28, 2010: http://www.epa.gov/pesticides/reregistration/status.htm]

Behavior in Fire: If water solution boils, poisonous hydrogen sulfide and highly flammable carbon disulfide vapors form. (USCG, 1999)

|Warning|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P272, P273, P280, P301+P312, P302+P352, P304+P340, P312, P321, P330, P333+P313, P363, P391, P403+P233, P405, and P501|H302 (92.4%): Harmful if swallowed [Warning Acute toxicity, oral]|Aggregated GHS information provided by 263 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Danger|P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P301+P312, P302+P352, P304+P340, P308+P313, P309+P311, P312, P314, P321, P330, P333+P313, P363, P391, P403+P233, P405, and P501

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: SMALL FIRE: Dry chemical, CO2, water spray or regular foam. LARGE FIRE: Water spray, fog or regular foam. Do not scatter spilled material with high-pressure water streams. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal. FIRE INVOLVING TANKS: Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent dust cloud. Avoid inhalation of asbestos dust. SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area. SMALL SPILL: Pick up with sand or other non-combustible absorbent material and place into containers for later disposal. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Cover powder spill with plastic sheet or tarp to minimize spreading. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2016)

Dust mask; self-contained breathing apparatus if compound is hot; goggles; rubber gloves. (USCG, 1999)|No nabam end-use products are within the scope of the Worker Protection Standard for Agricultural Pesticides (40 CFR parts 170 and 156). However, personal protective equipment for non-WPS occupational use is required.|The minimum (baseline) PPE for all occupational uses of nabam end use products is: Minimum PPE:Applicators and other handlers must wear: long-sleeve shirt and long pants, chemical-resistant gloves, socks plus shoes.|Engineering Control Requirements for liquid formulations: ... This product must be loaded and transferred only using a metering-pump system or a closed loading/application system for the following uses: air washer water systems; commercial/industrial water cooling systems (includes shipboard seawater cooling systems); evaporative condenser water systems; pasteurizer/warmer/cannery cooling water systems; and heat exchanger water systems.}. Open pouring is prohibited. For dry formulations: All nabam end-use products formulated as a dry formulation must be placed in water-soluble packaging.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|SRP: Contaminated protective clothing should be segregated in a manner that results in no direct personal contact by personnel who handle, dispose of, or clean the clothing. Quality assurance procedures to confirm the efficacy of the cleaning procedures should be implemented prior to the decontaminated protective clothing being returned for reuse by the workers. Contaminated clothing (including shoes/socks) should not be taken home at end of shift, but should remain at employee's place of work for cleaning.|Products Intended Primarily for Occupational Use. Do not apply this product in a way that will contact workers or other persons.|Products Intended Primarily for Occupational Use. If coveralls are required for pesticide handlers: Discard clothing or other absorbent materials that have been drenched or heavily contaminated with this product's concentrate. Do not reuse them.|For more Preventive Measures (Complete) data for Nabam (8 total), please visit the HSDB record page.

/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Health: TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. /Dithiocarbamate pesticide, liquid, flammable, poisonous; Dithiocarbamate pesticide, liquid, flammable, toxic; Dithiocarbamate pesticide, liquid, poisonous, flammable; Dithiocarbamate pesticide, liquid, toxic, flammable/|/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. /Dithiocarbamate pesticide, liquid, flammable, poisonous; Dithiocarbamate pesticide, liquid, flammable, toxic; Dithiocarbamate pesticide, liquid, poisonous, flammable; Dithiocarbamate pesticide, liquid, toxic, flammable/|/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Public Safety: CALL Emergency Response Telephone Number ... As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering. /Dithiocarbamate pesticide, liquid, flammable, poisonous; Dithiocarbamate pesticide, liquid, flammable, toxic; Dithiocarbamate pesticide, liquid, poisonous, flammable; Dithiocarbamate pesticide, liquid, toxic, flammable/|/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Dithiocarbamate pesticide, liquid, flammable, poisonous; Dithiocarbamate pesticide, liquid, flammable, toxic; Dithiocarbamate pesticide, liquid, poisonous, flammable; Dithiocarbamate pesticide, liquid, toxic, flammable/|For more DOT Emergency Guidelines (Complete) data for Nabam (16 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Contact with liquid irritates eyes ...|/Nabam is/ irritating to the skin and mucous membranes ...

U114; A toxic waste when a discarded commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or manufacturing chemical intermediate. /Ethylenebisdithiocarbamic acid, salts & esters/

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b). /Ethylenebisdithiocarbamic acid, salts and esters/

U114; As stipulated in 40 CFR 261.33, when ethylenebisdithiocarbamic acid, salts & esters, as a commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or a manufacturing chemical intermediate, becomes a waste, it must be managed according to Federal and/or State hazardous waste regulations. Also defined as a hazardous waste is any residue, contaminated soil, water, or other debris resulting from the cleanup of a spill, into water or on dry land, of this waste. Generators of small quantities of this waste may qualify for partial exclusion from hazardous waste regulations (40 CFR 261.5). /Ethylenebisdithiocarbamic acid, salts and esters/

highly toxic

Oils and alcohol increase the human absorption & toxicity.

LD50 Rat oral 395 mg/kg|LD50 Rat oral 1400 mg/kg|LD50 Rat ip 500 mg/kg|LC50 Rat inhalation 2.19 mg/L/4 hr|For more Non-Human Toxicity Values (Complete) data for Nabam (7 total), please visit the HSDB record page.

/BIRDS and MAMMALS/ Signs of intoxication /from acute oral administration to birds, goats, and bullfrogs (all symptoms may not be found in every species)/: ataxia, tremors, tachypnea, myasthenia, salivation, miosis, tenesmus, diarrhea, piloerection.|/BIRDS and MAMMALS/ Nabam was found to be practically nontoxic to birds on an acute oral and subacute dietary basis. To establish the toxicity of nabam to birds, the following tests /were/ required: one avian single-dose oral (LD50) study on one species (preferably mallard or bobwhite quail); one subacute dietary study (LC50) on one species (preferably the mallard duck or bobwhite quail).|/AQUATIC SPECIES/ Moderately toxic to fish.|/AQUATIC SPECIES/ To establish the toxicity of a pesticide to freshwater fish, the minimum data required/by the USEPA/ on the technical grade of the active ingredient is one freshwater fish toxicity study using either a coldwater fish (preferably the rainbow trout) or a warmwater fish (preferably the bluegill sunfish). Rainbow Trout, LC50 11ppm, and Bluegill Sunfish, LC50 28 ppm, Slightly Toxic, Static tests on 30% nabam. /From table/.|For more Ecotoxicity Excerpts (Complete) data for Nabam (9 total), please visit the HSDB record page.

Nabam's production may result in its release to the environment through various waste streams; its use as a fungicide(1) will result in its direct release to the environment(SRC).

TERRESTRIAL FATE: Nabam is decomposed by light, moisture, and heat(1,2). The major product of nabam abiotic decomposition is reported to be ethylenethiourea(2). Based on this rapid degradation, mobility in soil and volatilization are not expected to be important fate processes in the environment(SRC). Nabam exhibited a removal rate of 96% per day in activated sludge bench-scale reactors(3), indicating that biodegradation may be an important environmental fate process in soil(SRC).|AQUATIC FATE: Nabam is decomposed by light, moisture, and heat, and is unstable in aqueous solution(1,2). The major product of nabam abiotic decomposition is reported to be ethylenethiourea(2). Based on this rapid degradation, volatilization from water is not expected in the environment(SRC). According to a classification scheme(3), an estimated BCF of 3(SRC), from an estimated log Kow of -4.24(4) and a regression-derived equation(5), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Nabam exhibited a removal rate of 96% per day in activated sludge bench-scale reactors(6) indicating that biodegradation of nabam in water may be an important fate process(SRC).|ATMOSPHERIC FATE: Since nabam is a sodium salt(1), it will exist solely in the particulate phase in the ambient atmosphere. Particulate-phase nabam may be removed from the air by wet and dry deposition(SRC). Nabam absorbs light in the environmental UV spectrum(2) and therefore may be susceptible to direct photolysis by sunlight(SRC).

Nabam is decomposed by light, moisture, and heat, and is unstable in aqueous solution(1,2). The major product of nabam abiotic decomposition is reported to be ethylenethiourea(2).

An estimated BCF of 3 was calculated in fish for nabam(SRC), using an estimated log Kow of -4.24(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Nabam is decomposed by light, moisture, and heat, and is unstable in aqueous solution(1,2). The major product of nabam abiotic decomposition is reported to be ethylenethiourea(2). Based on this rapid degradation, mobility in soil is not expected to be an important fate process in the environment(SRC).

Volatilization from water surfaces, moist or dry soil is not expected given that nabam decomposes rapidly to ethylenethiourea(1).

Nabam was qualitatively found as a residue in samples tested during the Food and Drug Administration pesticide residue monitoring of various food samples for the test period of 1978-1982(1).|In 1989, 18,798 food samples were analyzed by the FDA for pesticide residues(1). Of these, only 1,278 samples were analyzed for EBDCs (ethylene bis-dithiocarbamates) in which nabam was detected; percent positive and concentrations not specified(1). Vegetables analyzed included peppers, leafy vegetables, cantaloupe, squash and peas(1). In 1990, the same study was conducted by the FDA but with 1,472 samples being analyzed for EBDCs; nabam was detected (percent positive and concentrations not specified)(2).

Occupational exposure to nabam may occur through dermal contact with this compound at workplaces where nabam is produced or used. The general population may be exposed to nabam via ingestion of food and dermal contact with fungicide products containing nabam. (SRC)

/Nabam is/ rapidly distributed in the mammalian system and /affects/ a variety of enzymes, phosphatase, phosphotransferase, and dopamine beta-hydroxylase. Most of the material is degraded and excreted ... . /Thiocarbamates/|... Radiolabelled nabam was administered to male and female rats by both oral and intravenous routes. Group A rats each received a single intravenous injection at 4.5 mg/kg; group B rats each received a single oral dose of 4.5 mg/kg. Each group C rat was dosed with 4.5 mg unlabelled nabam/kg/day, and then received 4.5 mg labelled nabam/kg on day 15. Each group D rat received a single dose of 100 mg labelled nabam/kg. For each group, most of the recovered radioactivity was in the urine (percentages ranged from 56.92 in group D males to 91.82 in group A females), with most of the remainder in the feces. Although the amount of radiolabelling in thyroids tended to be relatively low in terms of total administered (14)C (0.001% to 0.008%) concentrations were relatively high (10X to 31X) relative to carcass values. /Ethylene thiourea/ (ETU) was present in urine (11.7 to 36.6% of total (14)C present in the urine, with the highest percentages occurring in group D rats). No ETU was detected in the feces from group A animals; but 65.3% of the (14)C in the feces of group D males was from ETU; the value for group D females was 47.5%.|Nabam appears to be rapidly absorbed from the GI tract, distributed to target organs and excreted almost totally within 96 hr.|In a dermal absorption study ... male rats received 10 hr occluded exposures to 0.2%, 2%, and 20% (equal to 0.013, 0.13, and 1.3 mg/sq cm respectively) radiolabelled nabam in aqueous solutions; there was absorption of 0.24%, 0.05% and 0.08% of the label, respectively. Corresponding values for the amounts remaining on the skin (and presumably available for absorption) were 15.68%, 3.66%, and 1.09% respectively. It is noted that in a dermal absorption study for ETU ... "A significant portion of the dermal dose could not be washed off with soap and water and was subsequently absorbed."

... Radiolabelled nabam was administered to male and female rats by both oral and intravenous routes. Group A rats each received a single intravenous injection at 4.5 mg/kg; group B rats each received a single oral dose of 4.5 mg/kg. Each group C rat was dosed with 4.5 mg unlabelled nabam/kg/day, and then received 4.5 mg labelled nabam/kg on day 15. Each group D rat received a single dose of 100 mg labelled nabam/kg. For each group, most of the recovered radioactivity was in the urine (percentages ranged from 56.92 in group D males to 91.82 in group A females), with most of the remainder in the feces. Although the amount of radiolabelling in thyroids tended to be relatively low in terms of total administered (14)C (0.001% to 0.008%) concentrations were relatively high (10X to 31X) relative to carcass values. /Ethylene thiourea/ (ETU) was present in urine (11.7 to 36.6% of total (14)C present in the urine, with the highest percentages occurring in group D rats). No ETU was detected in the feces from group A animals; but 65.3% of the (14)C in the feces of group D males was from ETU; the value for group D females was 47.5%.|Cucumber seedlings were treated with Nabam via roots. Sap pressed from seedlings was chromatographed. Spots that appeared after development were chromatographically indistinguishable from ethylenethiourea. This could ... have been taken up from solution in which it may form spontaneously.|2-Imidazoline was tentatively identified as a minor conversion product of ethylenethiourea in cucumber and wheat seedlings and was assumed to be a terminal residue after root treatment with ethylenebisdithiocarbamate fungicides such as Nabam.|Studies with nabam, after application to soybeans, indicated the formation of ethyleneurea, 2,4-imidazolidinedione, 1-(2-imidaxolin-2-yl)-2-imidazolidinethione, and several other unidentified compounds.|For more Metabolism/Metabolites (Complete) data for Nabam (7 total), please visit the HSDB record page.

Contact with liquid irritates eyes and may cause mild to severe erythema of skin as well as sensitization reactions. (USCG, 1999)

INHALATION: remove to fresh air; administer artificial respiration and oxygen, if indicated. EYES: flush with copious quantities of water for 15 min.; call a physician. SKIN: wash thoroughly with soap and water. INGESTION: induce vomiting and follow with gastric lavage; get medical attention. (USCG, 1999)

Immediate first aid: Remove patient from contact with the material. Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Dithiocarbamates and Related Compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Dithiocarbamates and Related Compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or is in severe respiratory distress. Use moderate hyperventilation (rate of 20 respirations per minute) if signs of cerebral edema are present. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Dithiocarbamates and Related Compounds/|Gastrointestinal decontamination. If a large amount of the fungicide has been ingested in the last few hours, and if copious vomiting has not already occurred, it may be reasonable to consider GI decontamination. Activated charcoal can be used along with the addition of the cathartic sorbitol to the charcoal slurry. If sorbitol is given separately, it should be diluted with an equal volume of water before administration. No more than one dose of sorbitol is recommended and it should be used with caution in children and the elderly. If contact with the toxicant has been minimal (for example, oral contamination only, promptly flushed out of the mouth), administration of charcoal without a cathartic, followed by careful observation of the patient, probably represents optimal management. /Ethylene bis dithiocarbamates (EBDC compounds)/|For more Antidote and Emergency Treatment (Complete) data for Nabam (6 total), please visit the HSDB record page.

/HUMAN EXPOSURE STUDIES/ The irritant and allergic potential of most dithiocarbamates is evident in occupational exposure. Skin irritation and sensitization were studied in man using a conventional patch test. A cotton square was dipped in 19% nabam solution and placed on the inner surface of the forearm, and, 14 days later, this procedure was repeated on the opposite forearm. Zineb was tested in the same manner, except that the cotton square was dipped in 65% wettable powder. The patches were left in place for 48 hr. Of the 25 subjects included in the nabam study, 2 showed irritation (mild erythema and itching). Thirteen of the 25 reacted to the retest (from mild erythema to severe erythema, edema, and vesiculation), indicating sensitization. Of the 50 subjects used in the zineb study, no reaction at all was seen in 49 of them. One reacted in such a way that it indicated primary irritation rather than sensitization ...|/SIGNS AND SYMPTOMS/ It is irritating to the skin and mucous membranes, and it is /SRP: a CNS depressant/ in high concentrations.|/SIGNS AND SYMPTOMS/ Some applicators have experienced mild dermatitis, pharyngitis, rhinitis, bronchitis, and conjunctivitis from high exposure ... Skin irritation tests in humans showed reactions in 13 of 25 subjects including severe edema, erythema, vesiculation, and indications of development of sensitization reactions.|/SIGNS AND SYMPTOMS/ The ethylenebisdithiocarbamate (EBDC) compounds are not inhibitors of cholinesterase or of acetaldehyde dehydrogenase. They do not induce cholinergic illness or antabuse reactions. /Ethylenebisdithiocarbamates/|For more Human Toxicity Excerpts (Complete) data for Nabam (6 total), please visit the HSDB record page.

amobam

98% as a systemic fungicide on crops (fruit, nuts, and vegetables); and 2% in other applications (as a systemic fungicide on ornamentals, as a fungicide in the leather and paper industries, and as an intermediate for the fungicides Zineb, Maneb, Dithane M-45, and Manzate 200) (1975) /SRP: Former in USA/

A complete list of currently registered active pesticide products can be found in the National Pesticide Information Retrieval System's USEPA/OPP Registered and Cancelled Pesticide Product Database. These pesticide products are registered for use in the U.S. but approved products may change periodically and so federal, state and local authorities must be consulted for currently approved products.|AMA-9 (Kemira): Nabam 4.5%, Sodium dimethyldithiocarbamate 4.5%|AMA-30 (Kemira): Nabam 15%, Sodium dimethyldithiocarbamate 15%|Aquatreat DNM-9 (Akzo): Nabam 4.5%, sodium dimethyldithiocarbamate 4.5%|For more Formulations/Preparations (Complete) data for Nabam (9 total), please visit the HSDB record page.

Pesticide, fertilizer, and other agricultural chemical manufacturing|Carbamodithioic acid, N,N'-1,2-ethanediylbis-, sodium salt (1:2): ACTIVE|The WHO Recommended Classification of Pesticides by Hazard identifies Nabam (technical grade) as Class II: moderately hazardous; Main Use: fungicide, other than for seed treatment.|Superseded as protective fungicide by Zineb though the latter may be prepared by the mixing, in the field, of solutions of Nabam and of zinc sulfate.|In most countries, nabam has been superseded by zineb and maneb, because of the high phytotoxicity of nabam to plant foliage.

Method: AOAC 965.15; Procedure: carbon disulfide evolution method; Analyte: nabam; Matrix: pesticide formulations; Detection Limit: not provided.|GENERAL SAMPLE, REFLUX, SPECTROPHOTOMETRY @ 380 NM.|PRODUCT ANALYSIS /IS/ BY HYDROLYSIS TO CARBON DISULFIDE WHICH IS CONVERTED TO DITHIOCARBONATE & THIS MEASURED BY TITRATION WITH IODINE.|ETHYLENEBISDITHIOCARBAMATE RESIDUES IN CROPS. DETERMINATION OF ETHYLENE UREA IN FOODS. DETERMINATION OF ETHYLENE THIOUREA (ETU) RESIDUES.|For more Analytic Laboratory Methods (Complete) data for Nabam (7 total), please visit the HSDB record page.

Agrochemicals -> Fungicides, Herbicides