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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 743 qualified manufacturers and 379 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4831 Active Pharmaceutical Ingredients items

Flucytosine

CAS No: 2022-85-7

Formula: C4H4FN3O

Categories: Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Flucytosine (5-Fluorocytosine, 5-FC, Ancobon), a fluorinated pyrimidine analogue, is an antifungal drug.Target: antifungalFlucytosine, or 5-fluorocytosine, a fluorinated pyrimidine analogue, is a synthetic antimycotic drug. It is structurally related to the cytostatic fluorouracil and to floxuridine. It is available in oral and in some countries also in injectable form. A common brand name is Ancobon. Flucytosine was first synthesized in 1957 but its antifungal properties were discoveredMore

Ceftiofur

CAS No: 80370-57-6

Formula: C19H17N5O7S3

Categories: Active Pharmaceutical Ingredients > Antibiotics

Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals[1]. More

Empagliflozin

CAS No: 864070-44-0

Formula: C23H27ClO7

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Empagliflozin is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2. More

Calcitriol

CAS No: 32222-06-3

Formula: C27H44O3

Categories: Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines

Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist. More

Guaifenesin

CAS No: 93-14-1

Formula: C10H14O4

Categories: Active Pharmaceutical Ingredients > Respiratory Drugs

Guaifenesin is an expectorant that also has some muscle relaxing action.Target: OthersGuaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. It also stimulates the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx. Thus, it may increase the efficiency of the cough reflex and facilitate removal of the secretions; however, objectiveMore

Bismuth oxide (Bi2O3)

CAS No: 1304-76-3

Formula: Bi2O3

Categories: Active Pharmaceutical Ingredients > Digestive System Drugs

Bismuth oxide is an inorganic compound, odorless, stable in the air, with a molecular formula of Bi2O3. The pure products are α-type, β-type and δ-type. α-type is a yellow monoclinic crystal with a relative density of 8.9 and a melting point of 825 ℃. It is soluble in acid but insoluble in water and alkali; β-type is a bright yellow to orange tetragonal crystal with a relative density of 8.55 and a melting point of 860 ℃. It is soluble in acid but insoluble in water. It is easily reduced to metallic bismuth by hydrogen, hydrocarbons, etc.More

Latanoprost

CAS No: 130209-82-4

Formula: C26H40O5

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Latanoprost is an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP). More

Lamotrigine

CAS No: 84057-84-1

Formula: C9H7Cl2N5

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channelTarget: Sodium ChannelLamotrigine stabilises presynaptic neuronal membranes by blockade of voltage-dependent sodium channels, thus preventing the release of excitatory neurotransmitters, particularly glutamate and aspartate [1]. In rat cerebral cortex tissue incubated with veratrine 10 mg/L, lamotrigine is twice as potent in inhibiting the release of glutamate and aspartate (ED 50 = 5.38 mg/L forMore

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Bisacodyl

CAS No: 603-50-9

Formula: C22H19NO4

Categories: Active Pharmaceutical Ingredients > Digestive System Drugs

Bisacodyl is a stimulant laxative drug that works directly on the colon to produce a bowel movement.Target: OthersBisacodyl is an organic compound that is used as a stimulant laxative drug. Bisacodyl (20 mg/kg) results in a decrease in AQP3 protein expression and increased mRNA expression level of TNF-α in the colon of rats [1]. Bisacodyl inhibits water absorption in rat jejunum, ileum, and colon, the degree of inhibition is linearly related to the logarithm of the bisacodyl concentratioMore

Metformin hydrochloride

CAS No: 1115-70-4

Formula: C4H11N5.ClH

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Metformin (hydrochloride) is an FDA approved first-line drug for the treatment of type 2 diabetes. Metformin decreases hepatic glucose production, mostly through a mild and transient inhibition of the mitochondrial respiratory-chain complex 1. More

iodine

CAS No: 12190-71-5

Formula: I2

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Violet solid with a sharp, characteristic odor.More

Indomethacin

CAS No: 53-86-1

Formula: C19H16ClNO4

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. More

Tenofovir disoproxil

CAS No: 201341-05-1

Formula: C19H30N5O10P

Categories: Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. More

Doxazosin

CAS No: 74191-85-8

Formula: C23H25N5O5

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

Doxazosin(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.Target: Adrenergic ReceptorDoxazosin is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms [1]. doxazosin may have a direct inhibitory effect on cholesterol synthesis independent of the LDL receptor. The inhibition of cholesterol synthesis by doxazosin may cause cells to compensate by upregulMore

Roxithromycin

CAS No: 80214-83-1

Formula: C41H76N2O15

Categories: Active Pharmaceutical Ingredients > Antibiotics

Roxithromycin is a semi-synthetic macrolide antibiotic.Target: AntibacterialRoxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation ofMore

Retinol, acetate

CAS No: 127-47-9

Formula: C22H32O2

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

CrystallineRetinyl acetate (retinol acetate, vitamin A acetate) is a natural form of vitamin A. It is the acetate ester of retinol. It consists of yellow crystals which are greasy or sticky. It has a mild, characteristic odor. It has potential antineoplastic and chemo-preventive activities. It can be used to fortify food with vitamin A. As vitamin A acetate can induce cell differentiation and inhibit cell proliferation, it is used in skin-conditioning agent. More

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
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Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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