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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 743 qualified manufacturers and 379 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4831 Active Pharmaceutical Ingredients items

4-Piperidinemethanol

CAS No: 6457-49-4

Formula: C6H13NO

Categories: Active Pharmaceutical Ingredients > Other Chemical Drugs

white to off-white crystalline powder, chunksMore

Chloroethane

CAS No: 75-00-3

Formula: C2H5Cl

Categories: Active Pharmaceutical Ingredients > Anesthetic Agents

Chloroethane (also known as ethyl chloride) is a chemical compound with chemical formula C2H5Cl, and has been widely used in producing tetraethyllead, a gasoline additive. It is a colorless, flammable gas or refrigerated liquid with a faintly sweet odor.
Ethyl chloride is used in the production of ethyl cellulose, use as a solvent, refrigerant, and topical anesthetic, in the manufacture of dyes, chemicals, and pharmaceuticals, and as a medication to alleviate pain associated with insect bMore

Rivastigmine

CAS No: 123441-03-2

Formula: C14H22N2O2

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

ChEBI: A carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor.Rivastigmine (Exelon, EA 713) is apseudoirreversible noncompetitive carbamate inhibitor ofAChE. Although the half-life is approximately 2 hours,the inhibitory properties of this agent last for 10 hours becauseof the slow dissociation of the drug from the enzyme.The Food and Drug AdmiMore

Ranitidine hydrochloride

CAS No: 66357-59-3

Formula: C13H22N4O3S.ClH

Categories: Active Pharmaceutical Ingredients > Digestive System Drugs

Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production. Target: Histamine H2-ReceptorRanitidine (Zantac) is a histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 uM. It inhibits stomach acid production. It is also used alongside fexofenadine and other antihistamines for the treatment of skin conditions such as hives. It has 10% the affinity that cimetidine has to CYP450 so it causes fewer side effects, but other H2 blockers famotidine and nizatidine haMore

Sumatriptan

CAS No: 103628-46-2

Formula: C14H21N3O2S

Categories: Active Pharmaceutical Ingredients > Amides

ChEBI: A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor s btype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.Sumatriptan was the first triptan approved (1991) for theacute treatment of migraine headaches. It has the lowestoral bioavailability among all triptans becMore

Garlic oil

CAS No: 8008-99-9

Formula: C6H10S3

Categories: Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Garlic oil is obtained by steam distillation of crushed bulbs of the common garlic, Allium sativum L.; it is produced mainly in China, Mexico, India, Egypt, and, on a smaller scale, also in Europe (France,Hungary) and is a clear, reddish-orange liquid, with a strong, pungent, characteristic garlic odor. Garlic is an herbaceous, perennial plant of Mediterranean origin Its stalk can reach lengths of 1 m (39 in.) The plant exhibits fat, keeled leaves and is terminated by an umbellated fower clusteMore

Estradiol valerate

CAS No: 979-32-8

Formula: C23H32O3

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs. More

Doxazosin mesylate

CAS No: 77883-43-3

Formula: C23H25N5O5.CH4O3S

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

Doxazosin mesylate(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.Target: α1-adrenergic receptorDoxazosin (mesylate) is the mesylate salt form of doxazosin, which is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms [1]. doxazosin may have a direct inhibitory effect on cholesterol synthesis independent of the LDL receptor. The inhibition of cholesMore

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Ceftriaxone

CAS No: 73384-59-5

Formula: C18H18N8O7S3

Categories: Active Pharmaceutical Ingredients > Antibiotics

Ceftriaxone is an antibiotic useful for the treatment of a number of bacterial infections.Target: AntibacterialCeftriaxone inhibits bacterial cell wall synthesis by means of binding to the penicillin-binding proteins (PBPs). Inhibition of PBPs would in turn inhibit the transpeptidation step in peptidoglycan synthesis which is required for bacterial cell walls. Like other cephalosporins, ceftriaxone is bacteriocidal and exhibits time-dependent killing. Ceftriaxone, one of the beta-lactamMore

DL-α-Tocopherol

CAS No: 10191-41-0

Formula: C29H50O2

Categories: Active Pharmaceutical Ingredients > Antioxidant Ingredient

DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1]. More

Yohimbine hydrochloride

CAS No: 65-19-0

Formula: C21H26N2O3.ClH

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Yohimbine hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.IC50 value:Target:In vitro:In vivo: Yohimbine hydrochloride (0.2 mg/kg, i.p.) was administered to rats 1h before the stress session daily for 14 consecutive days and its effect was assessed. Results of this section revealed that, immersion of rats in cold water significantly decreased sexual arousal andMore

Voglibose

CAS No: 83480-29-9

Formula: C10H21NO7

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.Target: α-glucosidasesglibose can inhibit the intestinal α-glucosidases, which are responsible for the digestion of disaccharides such as maltose and sucrose, including maltase and sucrase. The Ki values of Voglibose for sucrase and maltase are about 106and 105 times smaller than the Km values forMore

ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate;hydrate;hydrochloride

CAS No: 868364-57-2

Formula: C22H28BrClN2O4S

Categories: Active Pharmaceutical Ingredients > Urinary System Drugs

Piperidine, hydrochloride

CAS No: 6091-44-7

Formula: C5H11N.ClH

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

WHITE FINE CRYSTALLINE POWDERMore

Olopatadine

CAS No: 113806-05-6

Formula: C21H23NO3

Categories: Active Pharmaceutical Ingredients > Antiallergic Drugs

Olopatadine belongs to a kind of antihistamine reagent. It is a relatively selective H1-receptor antagonist and can inhibit the histamine release process from the mast cell, subsequently leading to temporary relief on the negative symptoms associated with histamine. It is devoid of effects on alpha-adrenergic, dopamine and muscarinic type I and II receptors. Its 0.1% solution can be used for topical administration to the eyes. It is indicated for the treatment of itching associated with allergiMore

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

    40.0Yuan/kg -

Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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