Levothyroxine Sodium Tablets

Thyroid hormone drugs. This product is a synthetic sodium tetraiodothyronine, which is converted into triiodothyronine (T3) in the body and its activity is enhanced. It has the functions of maintaining normal growth and development of the human body, promoting metabolism, increasing heat production and improving the sensitivity of the sympathetic-adrenal system.

The main ingredient of this product is levothyroxine sodium

This product is white tablets.

It is suitable for long-term replacement therapy of congenital hypothyroidism (cretinism) and hypothyroidism caused by various reasons in children and adults. It can also be used for simple goiter, chronic lymphocytic thyroiditis, and suppression (and replacement) therapy after thyroid cancer surgery. Sometimes it can be used as an adjuvant therapy for hyperthyroidism and can also be used for thyroid suppression tests.

For adults, the initial daily dose is 25-100 μg, which can be increased by 25-50 μg every 2-4 weeks until normal metabolism is maintained. The general maintenance dose is 50-200 μg/day. For elderly patients or patients with cardiovascular diseases, the initial dose is 12.5-25 μg, which can be increased every 3-4 weeks, with each increase of 12.5-25 μg. After administration, the patient should be closely observed for increased heart rate, arrhythmia, and changes in blood pressure. If necessary, the dose should be temporarily increased or reduced. For newborns and children with hypothyroidism or cretinism, refer to the following table for dosage: Recommended dosage (daily): 0-6 months 25-50 micrograms (8-10 micrograms/kg body weight) 7-12 months 50-70 micrograms (6-8 micrograms/kg body weight) 2-5 years old 75-100 micrograms (5-6 micrograms/kg body weight) 6-12 years old 100-150 micrograms (4-5 micrograms/kg body weight) 12 years old and above 150-200 micrograms (2-3 micrograms/kg body weight) or follow the doctor's advice. Increase the dose (12.5 μg-25 μg) every 2-4 weeks until the clinical manifestations are completely normal. Normal pulse rate or normal stool is a good clinical observation indicator.

Symptoms of overdose include angina pectoris, arrhythmia, palpitations, diarrhea, vomiting, tremor, excitement, headache, restlessness, insomnia, sweating, hot flashes, weight loss, skeletal muscle cramps, etc. These symptoms usually disappear after reducing the dosage or stopping the drug for a few days.

It is contraindicated for patients with non-hypothyroid heart failure, tachyarrhythmias, recent myocardial infarction, and those who are allergic to the drug.

Precautions for children: For neonates and children with hypothyroidism or cretinism, refer to the following table for dosage: Recommended dosage (daily) or follow doctor's advice: Age Daily dosage (mg) By weight (mg/kg) 0-6 months 25-50 micrograms (8-10 micrograms/kg body weight) 7-12 months 50-70 micrograms (6-8 micrograms/kg body weight) 2-5 years old 75-100 micrograms (5-6 micrograms/kg body weight) 6-12 years old 100-150 micrograms (4-5 micrograms/kg body weight) 12 years old and above 15 Precautions for pregnancy and lactation: Special attention should be paid to continued use of thyroxine during pregnancy and lactation; levothyroxine and antithyroid drugs should not be used together to treat hyperthyroidism during pregnancy, because the addition of levothyroxine will increase the dose of antithyroid drugs. Unlike levothyroxine, antithyroid drugs can cross the placenta and reduce fetal thyroid function. Precautions for the elderly: The dosage of levothyroxine sodium tablets must be used with great caution in elderly patients. They should start with a small dose and increase the dose at longer intervals, that is, increase the dose slowly, and monitor blood thyroxine levels regularly.

1. Levothyroxine sodium will increase the anticoagulant effect; 2. Levothyroxine sodium will increase the level of phenytoin sodium in the blood; 3. Anticonvulsants such as carbamazepine and phenytoin sodium accelerate the metabolism of levothyroxine sodium and can replace thyroxine from plasma proteins; 4. This product is used together with cardiac glycosides, and the dosage of cardiac glycosides must be adjusted accordingly; 5. Levothyroxine sodium will also increase the effect of sympathomimetic drugs; 6. Levothyroxine sodium increases the sensitivity of catecholamine receptors, thereby enhancing the effect of tricyclic antidepressants; 7. Cholestyramine reduces the absorption of levothyroxine sodium. If oral contraceptives are used at the same time, the dosage of this product needs to be increased.

Keep away from light and store in a sealed container below 25℃.

50μg

36 months

Shenzhen Zhonglian Pharmaceutical Co., Ltd.

• Founded in:

  1988-10-11

• Address:

  Room 401, Building 1, Block B, No. 9 Danqing Road, Jinsha Community, Kengzi Street, Pingshan District, Shenzhen (One license, multiple locations enterprise)

• Tax NO.:

  91440300192188676Y

• Registered Funds:

  120 million yuan

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