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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Ledipasvir for Sale > Supply 99% Ledipasvir CAS 1256388-51-8
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Supply 99% Ledipasvir CAS 1256388-51-8

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CAS No.:

1256388-51-8

Grade:

Pharmaceutical grade

Content:

99%

Port:

Xi'an

Brand:

TGY

Packaging:

1kg/foil bag,25kg/Cardboard Drum

Price valid (until):

2023-06-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Product Name:Ledipasvir
    CAS:1256388-51-8
    MF:C49H54F2N8O6
    MW:889
    EINECS:1592732-453-0


    Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). After completing Phase III clinical trials, on February 10, 2014 Gilead filed for U.S. approval of a ledipasvir/sofosbuvir fixed-dose combination tablet for genotype 1 hepatitis C.The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication and can be used to treat patients with genotypes 1a or 1b without PEG-interferon or ribavirin.


    Function:

    Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion, a hepatitis C virus protein.

    Application:

    Ledipasvir is an orally available inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) replication complex, ledipasvir is indicated for the treatment of HCV genotypes 1, 4, 5, and 6. Its use has also proven successful in the treatment of HCV in patients co-infected with HIV

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    Basic Info
    Product Name:

    Ledipasvir

    Other Name:

    Carbamic acid,N-[(1S)-1-[[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-6-yl]-9H-fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]carbonyl]-2-methylpropyl]-,methyl ester;GS 5885;Ledipasvir;1350473-66-3

    CAS No.:

    1256388-51-8

    Molecular Formula:

    C49H54F2N8O6

    InChIKeys:

    InChIKey=VRTWBAAJJOHBQU-KMWAZVGDSA-N

    Molecular Weight:

    889.02

    Exact Mass:

    889.00

    EC Number:

    1592732-453-0

    UNII:

    013TE6E4WV

    DSSTox ID:

    DTXSID90154829

    NCI Thesaurus Code:

    C129019

    ATC Code:

    J05AX65

    HScode:

    29333990

    Characteristics
    PSA:

    175

    XLogP3:

    7.4

    Density:

    1.42±0.1 g/cm3(Predicted)

    Refractive Index:

    1.677

    Dissociation Constants:

    pka1 = 4.0, pka2 = 5.0

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

    Location:

    I-City unit 3, South of Tangyan Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2015

    Certifications:

    HACCP,Halal,GMP,ISO

    Company Profile

    XI'AN TIANGUANGYUAN BIOTECH CO., LTD. is specialized in researching, producing and selling Herbal Extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and Food Additives etc. Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. It is aiming of benefiting the world with lowest price but best products.We are keeping overcritical on the quality and persisting in the profession all the time. TGY owns two standardized production workshops, advanced multi-function extractors and juice concentrate equipment, covering 12,000㎡ annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service.


    So far, we have 10 years experience for export in this field and have good relationship with regular customers from countries and regions in the world. Our company has got independent Import & Export License and has built good relationship with international expresses, as well as some air and sea shipping agents to provide timely and professional service for all clients.

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