Oseltamivir acid
187227-45-8
0.98%
2026-08-13
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Oseltamivir acid Cat No CEI-1455 Product Overview Oseltamivir is an inhibitor of influenza neuraminidase. Oseltamivir is a prodrug that is converted by intestinal and/or hepatic esterases to the neuraminidase inhibitor molecule, oseltamivir carboxylate. Neuraminidase cleaves the terminal a-Neu5Ac residues from the newly synthesized virion progeny and let it elute from the infected cell and seek new host cells to infect. Oseltamivir efficiently block sialidase activity and significantly inhibit the releasing mechanism. In the treatment of adults, oseltamivir reduces the time to first alleviation of symptoms and investigator mediated unverified pneumonia. In prophylaxis trials, oseltamivir reduced symptomatic influenza in participants by 55%. Oseltamivir also has some harm. Adults treated with oseltamivir are associated with an increased risk of nausea. And in prophylaxis trials there is an increased risk of headaches on-treatment. As a neuraminidase inhibitor, the substitution of the amino acid histidine to tyrosine at position 275 (H275Y) in the neuraminidase gene of H1N1 can cause the resistance of oseltamivir. CAS No 187227-45-8 Molecular Weight 284.35 Purity 0.98 Storage Store at -20°C Synonyms GS 4071; Ro 64-0802 Targets Influenza neuraminidase Molecular Formula C14H24N2O4 Chemical Name (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylic acid Solubility Soluble in DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Standard(c2411) cas_num 187227-45-8 Basic Info-
Product Name:
Ro 64-0802
Other Name:1-Cyclohexene-1-carboxylic acid,4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-,(3R,4R,5S)-;1-Cyclohexene-1-carboxylic acid,4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-,[3R-(3α,4β,5α)]-;(3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid;GS 4071;Ro 64-0802;Oseltamivir acid
CAS No.:187227-45-8
Molecular Formula:C14H24N2O4
InChIKeys:InChIKey=NENPYTRHICXVCS-YNEHKIRRSA-N
Molecular Weight:284.354
Exact Mass:284.35
UNII:K6106LV5Q8
DSSTox ID:DTXSID50171996
ATC Code:J05AH02
Categories:
Characteristics-
PSA:
102
XLogP3:0.45
Density:1.15±0.1 g/cm3(Predicted)
Melting Point:185-187 °C
Boiling Point:508.7±50.0 °C(Predicted)
Flash Point:261.5±30.1 °C
Refractive Index:1.525
Storage Conditions:-20°C Freezer, Under Inert Atmosphere
Vapor Pressure:1E-11mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product