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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > (±)-Lipoic acid for Sale > China Largest factory Manufacturer Supply Alpha Lipoic Acid CAS 1077-28-7
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China Largest factory Manufacturer Supply Alpha Lipoic Acid CAS 1077-28-7

GMP HALAL KOSHER ISO FDA TDS 13 Inquiries

Unit Price: Get Latest Price
CAS No.:

1077-28-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Leader

Packaging:

25KG/Drum

Price valid (until):

2023-12-14

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      About Product Technical Details  


    α-Lipoic Acid Chemical Properties
    Melting point  60-62 °C
    Boiling point  160-165 °C(lit.)
    density  1.2888 (rough estimate)
    refractive index  1.5200 (estimate)
    Fp  160-165°C
    storage temp.  2-8°C
    solubility  ethanol: 50 mg/mL
    pka 4.75±0.10(Predicted)
    form  Crystals or Crystalline Powder
    color  Yellow
    Water Solubility  0.9 g/L (20 ºC)
    Merck  14,9326
    BRN  81853
    Stability: Stable. Incompatible with strong oxidizing agents.
    InChIKey AGBQKNBQESQNJD-UHFFFAOYSA-N
    LogP 2.530 (est)
    CAS DataBase Reference 1077-28-7(CAS DataBase Reference)
    NIST Chemistry Reference Dl-thioctic acid(1077-28-7)

    Safety Information
    Hazard Codes  Xn
    Risk Statements  22-20/21/22
    Safety Statements  37/39-26-24/25-36-36/37/39
    WGK Germany  3
    RTECS  JP1192000
    HS Code  29349990


      Product Pictures  


    Shop China Largest factory Manufacturer Supply Alpha Lipoic Acid CAS 1077-28-7-Detailed Image 1

    Shop China Largest factory Manufacturer Supply SODIUM SURFACTIN CAS 302933-83-1/24730-31-2-Detailed Image 3


      About Our Group


         Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry,  pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products. All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.


      Our Factories Production Lines  



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    Certificates
    • China Largest factory Manufacturer Supply Alpha Lipoic Acid CAS 1077-28-7 Certificates 7

    Basic Info
    Product Name:

    (±)-Lipoic acid

    Other Name:

    1,2-Dithiolane-3-pentanoic acid;1,2-Dithiolane-3-valeric acid,(±)-;1,2-Dithiolane-3-pentanoic acid,(±)-;dl-Thioctic acid;DL-α-Lipoic acid;DL-6-Thioctic acid;DL-6,8-Thioctic acid;(±)-Thioctic acid;(±)-α-Lipoic acid;DL-Thioctic acid;(RS)-Lipoic acid;(RS)-α-Lipoic acid;5-(1,2-Dithiolan-3-yl)pentanoic acid;5-(1,2-Dithiolan-3-yl)valeric acid;Protogen A;Pyruvate oxidation factor;Thioctacid;Thioctic acid;6,8-Thioctic acid;Tioctidasi;Tioctidasi acetate replacing factor;1,2-Dithiolane-3-valeric acid;6-Thioctic acid;α-Liponic acid;Tioctacid;Biletan;Thioctsan;Liposan;Lipothion;(±)-Lipoic acid;NSC 628502;dl-Lipoic acid;NSC 90788;Alipure;Espa-lipon;Thiotacid;dl-α-Lipoic acid;α-lipon 300;α-(±)-Lipoic acid;DL-Lipoic acid;Byodinoral-R;Octolipen;Oktolipen;62-46-4;27779-68-6

    CAS No.:

    1077-28-7

    Molecular Formula:

    C8H14O2S2

    InChIKeys:

    InChIKey=AGBQKNBQESQNJD-UHFFFAOYSA-N

    Molecular Weight:

    206.32600

    Exact Mass:

    206.33

    EC Number:

    200-534-6

    NSC Number:

    758651|90788

    DSSTox ID:

    DTXSID7025508

    Color/Form:

    Forms yellowish flakes

    ATC Code:

    A - Alimentary tract and metabolism

    HScode:

    2934999090

    Characteristics
    PSA:

    87.90000

    XLogP3:

    2.78510

    Appearance:

    light yellow to yellow powder

    Density:

    1.218g/cm3

    Melting Point:

    60-61 °C

    Boiling Point:

    160-165 °C

    Flash Point:

    173ºC

    Refractive Index:

    1.562

    Water Solubility:

    ethanol: 50 mg/mL | 0.9 g/L (20 ºC);In water, 127 mg/L at 25 deg C (est)

    Storage Conditions:

    2-8ºC

    Vapor Pressure:

    9.49X10-1 mm Hg at 25 deg C (est)

    Henrys Law Constant:

    Henry's Law constant = 1.64X10-8 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 5.10|pKa = 4.70 (carboxy) (est)

    Collision Cross Section:

    133.8 Ų [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]

    Experimental Properties:

    White powder, soluble in water, pH of aqueous solutions about 7.4 /Thioctic acid, sodium salt/|Crystals by vacuum sublimation (at 85-90 °C and 25 micron). MP: 46-48 °C (microblock). Specific optical rotation: + 104 deg at 23 °C/D (c = 0.88 in benzene). UV max (methanol): 333 nm (epsilon 150). pKa = 5.4. Practically insoluble in water. Soluble in fat solvents. /Thioctic acid, d-form/|Yellow needles from cyclohexane. MP: 60-61 °C. BP: 160-165 °C. Practically insoluble in water; soluble in fat solvents. Forms a water-soluble sodium salt. /Thioctic acid, dl-form/|Crystals from cyclohexane. MP: 45-47.5 °C (microblock). Specific optical rotation: -113 deg at 23 °C/D (c = 1.88 in benzene). UV max (methanol): 330 nm (epsilon 140). /Thioctic acid, l-form/|Hydroxyl radical reaction rate constant = 2.52X10-10 cu m/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin irritation, Category 2

    Skin sensitization, Category 1

    Eye irritation, Category 2

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H315 Causes skin irritation

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

    Location:

    National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2014

    Certifications:

    Level A of Tax Credit Registration Assessment by Government,Good Product Quality Management Certificate of Shanxi Province,China,Company Trade Union Qualification Certificate,Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina,AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China,FDA


    24 Hours Team Service

    Email

    info@leader-biogroup.com   

    Hot Line

    +86-029-68895030  

    +86-029-68569961  

    +86-029-68569962  

    Fax

    +86-029-68895030


    Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.

    • Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.

      Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.

      Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

      We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

    • Process Capability :   It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.

                                      

        Factory Overview

                                                                                 Factory Production Lines

    Our Professional Lab

                               Factory Warehouse 

    Factory Logistics Departments

    GROUP HONOR

    Honor Name: Level A of Tax Credit Registration Assessment   
    Issued By:National Administration of Taxation & Shaanxi Tax Bureau   
    Authorised Date:2018-09-16  
    Description: National Administration of Taxation & Shaanxi Tax Bureau




    Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China  
    Issued By:China Association of Shaanxi product Quality management Center   
    Authorised Date:2018-12-31  
    Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China



    Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina

    Issued By: China Association of Shaanxi product Quality management Center

    Authorised Date:2018-12-31

    Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China



    Honor Name: Products Patent Certificates


  • Inquiry History
    13 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    DL-Thioctic acid

    25 KG Jan 6, 2025
    Turkey

    Thioctic Acid

    600 MG Feb 25, 2025
    Egypt

    Alpha Lipoic Acid Powder

    200.00 KG Feb 24, 2025
    Thailand

    Alpha Lipoic Acid

    1 KG Jan 22, 2025
    India

    Alpha Lipoic Acid

    300 KG Dec 26, 2024
    India

    Alpha Lipoic Acid

    5000 KG Dec 20, 2024
    India

    ALPHA LIPOIC ACID

    200 KG Nov 22, 2024
    India

    Factory Price Alpha Lipoic Acid ALA 99% from China

    500 MT Oct 22, 2023
    Brazil

    Alpha L Acid

    1 KG Apr 16, 2026
    India

    Alpha Lipoic Acid

    500.00 KG Jun 28, 2024
    Egypt

    alpha lipoic acid

    2 MT Jul 21, 2024
    Egypt

    Thioctic acid 99% Yellow powder

    500 KG Oct 18, 2023
    Turkey

    Factory Price Alpha Lipoic Acid ALA 99% from China

    200 KG Aug 2, 2023
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