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deferasirox 98%

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CAS No.:

201530-41-8

Content:

99%

Port:

Shanghai

Packaging:

25kg/Cardboard Drum

Price valid (until):

2025-04-27

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Conier Chem&Pharma Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Dicobalt Octacarbonyl,(E,E)-Farnesol,(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,Geranyl linalool

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Product Description
Seller Information
Inquiry History

Description

Deferasirox Chemical Properties

Melting point	260-2620C
Boiling point	672.1±65.0 °C(Predicted)
density	1.40±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Soluble in DMSO (10 mg/ml)
pka	pKa1 4.57, pKa2 8.71, pKa3 10.56 (Nick); Also reported in H2O/DMSO (CDMSO = 0.20) as pKa1 4.61, pKa2 10.12, pKa3 12.08 (Steinhauser)
form	solid
color	Off-white to white
Stability:	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

HS Code	2933997500
Hazardous Substances Data	201530-41-8(Hazardous Substances Data)

Uses

1. DFS can be used to treat the reversible renal insufficiency caused by Fanconi syndrome.
2. It can be used for the treatment of secondary hemochromatosis.
3. It can be used for the treatment of delayed skin porphyria.
4. It can be used for the treatment of myelodysplastic syndromes.
5. It can be used for the treatment of iron overloading caused by blood transfusion for patients (older than 2 years old) of chronic anemia This information is compiled and edited by Ding Hong of Chemicalbook. (2015-09-18)

Precautions

Patients with allergy to deferasirox are disabled.

Pls input...

Items	Specifications
Appearance	White to Off-White Solid

Basic Info

Product Name:

Deferasirox

Other Name:

Benzoic acid,4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-;4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid;ICL 670A;ICL 670;Deferasirox;4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid;Exjade;Asunra;Jadenu

CAS No.:

201530-41-8

Molecular Formula:

C21H15N3O4

InChIKeys:

InChIKey=BOFQWVMAQOTZIW-UHFFFAOYSA-N

Molecular Weight:

373.3615

Exact Mass:

373.36

EC Number:

1806241-263-5

UNII:

V8G4MOF2V9

DSSTox ID:

DTXSID1048596

NCI Thesaurus Code:

C48384

Color/Form:

Crystals from ethanol|White to slightly yellow powder

ATC Code:

V03AC03|V - Various

HScode:

2933990090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

109 Å²

XLogP3:

log Kow = 6.30 (pH 7.4)|3.52

Density:

1.4±0.1 g/cm3

Melting Point:

260-2620C

Boiling Point:

651°C at 760 mmHg

Flash Point:

360.3±34.3 °C

Refractive Index:

1.699

Water Solubility:

In water, 0.4 mg/mL at 25 °C (pH 7.40)|3.43e-02 g/L

Storage Conditions:

-20°C Freezer

Vapor Pressure:

1.67X10-13 mm Hg at 25 °C (est)

Henrys Law Constant:

Henry's Law constant = 1.4X10-17 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = 4.57; pKa2 = 8.71; pKa3 = 10.56|Dissociation constant also reported in H2O/DMSO (X(DMSO = 0.20) as pKa1 = 4.61; pKa2 = 10.12; pKa3 = 12.08

Experimental Properties:

Hydroxyl radical reaction rate constant = 2.05X10-10 cu cm/molec-sec at 25 °C (est)

See More Deferasirox Properties 

Hazard Identification

Classification of the substance or mixture

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H410 Very toxic to aquatic life with long lasting effects
Prevention	P273 Avoid release to the environment.
Response	P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Deferasirox Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Dicobalt Octacarbonyl,(E,E)-Farnesol,(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,Geranyl linalool

Location:
11F ,#20 building, #18 Fuquan Road ,Jiangbei District, CHONGQING 400020, P.R China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
350

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2010

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Deferasirox	25 KG	Mar 19, 2024
Hongkong, China	Deferasirox is an iron chelator (binder)	5000 KG	May 12, 2025

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