Palmitoyl Tripeptide-8 99% White powder

Palmitoyl-Lysyl-Valyl-Lysine (Pal-Lys-Val-Lys-OH), also known as "Tripeptide" or "Collagen Peptide COLL-O2," is among the earliest and most widely utilized cosmetic peptides.

Effects and Functions

Palmitoyl-Lysyl-Valyl-Lysine belongs to the category of signaling peptides. It can promote the synthesis of collagen (Types I, II, and IV) and the production of extracellular matrix proteins by enhancing the activity of matrix cells, resulting in skin that appears younger and more elastic. When added to cosmetics, it aids in replenishing collagen in the skin, improving facial elasticity, and significantly reducing facial wrinkles. Additionally, it has the properties of enhancing cell activity, increasing skin moisture content, boosting skin radiance, and improving skin tone. It elevates skin hydration and moisture retention, leaving the skin feeling soft, smooth, and supple, while brightening the complexion from within to eliminate dullness.

Applications

Palmitoyl-Lysyl-Valyl-Lysine can inhibit melanin production within melanocytes by suppressing tyrosinase activity and downregulating the mRNA levels of Microphthalmia-associated Transcription Factor (MITF) and tyrosinase, making it a potential candidate for use as a whitening additive in the cosmetic industry. Clinical trials have demonstrated that skincare products containing Palmitoyl-Lysyl-Valyl-Lysine significantly reduce skin sagging and diminish and modify age-related wrinkles when compared to placebos and reference substances. It exhibits notably higher activity compared to 10 ppm Palmitoyl Pentapeptide-4. This ingredient has been included in the 2015 Inventory of Existing Cosmetic Ingredients in China and can be legally added to cosmetic products.