*Product Photos
Product Introduction
| Item | Details |
| CAS No. | 448944-47-6 |
| Names | Acetyl Hexapeptide-1 (Melitane, Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2) |
| Purity | >99 |
1. Product Overview
Acetyl Hexapeptide-1, whose common aliases include Melitane and Stellight, has a chemical sequence name of Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH₂, with the corresponding CAS number 448944-47-6. The molecular formula is C₃₉H₅₈N₁₂O₇, and the molecular weight is 806.96. The product appears as a white to off-white powder in a free-state (non-copper complexed) form. The high-purity specification is ≥98.0% (tested by HPLC), with a peptide content of ≥80.0%, an acetate content ranging from 5.0% to 12.0%, and a moisture content of ≤8.0%. It is highly soluble in water, forming a colorless and transparent solution after dissolution, which is compatible with various water-based skincare formulations.
2. Core Functions and Mechanisms of Action
As a highly active signal peptide, Acetyl Hexapeptide-1’s core functions focus on skin rejuvenation and maintenance, with scientific and clear mechanisms of action. Firstly, in terms of anti-wrinkle and skin smoothing, it regulates the rhythm of skin keratin metabolism, promotes the natural shedding of aged cuticles, improves skin roughness and obvious fine lines, especially exerting a significant soothing effect on dry lines and fine lines, leaving the skin delicate and smooth. Secondly, it has remarkable skin brightening effects, which can inhibit the activity of factors related to skin dullness, reduce pigmentation accumulation, enhance skin translucency, improve uneven and dull skin tone, and present a naturally bright skin state with long-term use. Thirdly, it helps repair the skin barrier by gently promoting the synthesis of skin barrier lipids, enhancing the skin's moisture-locking capacity and improving its tolerance to external stimuli. It is particularly suitable for the daily conditioning of sensitive and dry skin, being gentle and non-irritating. In addition, it optimizes the overall skin condition, regulates the balance of the skin microenvironment, maintains the skin's moisture and elasticity, and delays the initial aging problems caused by dryness and slow metabolism, meeting the skincare needs of all age groups and various skin types.
3. Application Scenarios
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Acetyl Hexapeptide-1’s application scenarios are mainly concentrated in the cosmetic field, and can also be extended to pharmaceutical intermediates and biological research reagents. In the cosmetic field, it is first applicable to anti-aging and brightening skincare products, such as serums, creams, eye creams, facial masks, toners and lotions. It can be used as a core active ingredient, focusing on anti-wrinkle, brightening, barrier repair and skin stabilization, suitable for mid-to-high-end skincare series and daily care products for the public, compatible with all skin types including dry, normal, combination and sensitive skin. In other fields, Acetyl Hexapeptide-1 can be used as a pharmaceutical intermediate for the R&D and production of topical skin conditioning preparations; it can also be used as a biological research reagent in scientific experiments related to skin metabolism and barrier repair.
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4. Packaging
We offer flexible and customizable packaging options to meet the diverse needs of different orders and customers.
5. Storage Requirements
To maximize the activity, stability, and shelf life of Acetyl Hexapeptide-1, the following storage requirements must be strictly followed. Regarding temperature control, long-term storage (more than 3 months) is recommended to be stored at -20℃ under freeze-dried and light-proof conditions, which can effectively extend the product shelf life; short-term storage (≤3 months) can be stored in sealed refrigeration at 2-8℃, avoiding excessive temperature fluctuations. The storage environment should be dry, well-ventilated, and cool, with relative humidity controlled at ≤60%, away from heat sources, fire sources, oxidants, and acids and alkalis to prevent product oxidation, deterioration, or chemical reactions. The storage container must always be kept in a vacuum or sealed state to avoid air and moisture entering, leading to product moisture absorption and oxidation; after opening the product, it should be used as soon as possible, and the remaining part should be tightly resealed and stored back in the corresponding temperature environment to reduce the contact time with air. In terms of shelf life, unopened products have a shelf life of 2 years when stored at -20℃ and 1 year when stored at 2-8℃; it is recommended to use the product within 1 month after opening to ensure that the product activity is not affected.
