—— Product Specifications ——
Parameter | Specification | Details / Test Method |
Purity (HPLC) | ≥95% | Standard test method for purity (hplc) |
Melting Point | 198-202°C | Differential Scanning Calorimetry (DSC) |
Loss on Drying | ≤1.0% | Gravimetric method, 105°C for 2 hours |
Residue on Ignition | ≤0.5% | Gravimetric method, 600°C ignition |
Heavy Metals | ≤10ppm | ICP-MS method, max 10 ppm as Pb |
Appearance | White powder | Visual inspection at room temperature |
Solubility | Freely soluble in DMSO, soluble in ethanol | Tested in various solvents at 25°C |
Storage Temperature | 2-8°C | Standard test method for storage temperature |
Molecular Weight | 259.31 g/mol | Calculated from molecular formula |
Chemical Formula | C14H17N3O2 | Standard test method for chemical formula |
Appearance Time | ≥24 months (sealed, cool storage) | Standard test method for appearance time |
Shelf Life | Two years | 24 months from date of manufacture under proper storage |
—— Product Detail ——
Product Overview
This compound is a pharmaceutical intermediate featuring a diazepane core structure with a 4-aminophenyl substituent. The molecule contains a seven-membered heterocyclic ring containing two nitrogen atoms, with a methyl group at position 3 and an aminophenyl group at position 4. This structural arrangement provides specific chemical reactivity and potential biological activity. The compound is primarily used in pharmaceutical research and development as a key building block for the synthesis of novel therapeutic agents. Its unique heterocyclic framework makes it valuable in medicinal chemistry for developing compounds targeting various diseases. The presence of both amino and carbonyl functional groups allows for diverse synthetic transformations.
Synthesis Process
The synthesis of this compound typically involves a multi-step process starting from commercially available materials. The diazepane ring is constructed through cyclization reactions, followed by sequential introduction of the methyl and 4-aminophenyl substituents. Key steps include N-protection, carbonyl group formation, and deprotection reactions. The process requires careful control of reaction conditions including temperature, pH, and solvent selection to achieve optimal yield and purity. Purification is achieved through column chromatography or recrystallization methods.
Quality Specifications
The product meets pharmaceutical grade specifications with purity typically above 95%, with HPLC verification. Key quality parameters include: Appearance as white powder, melting point within specified range, loss on drying below 1.0%, residue on ignition below 0.5%, heavy metals below 10ppm, and specific rotation within acceptable range for chiral compounds. Each batch is accompanied by comprehensive Certificate of Analysis including IR, NMR, and mass spectrometry data.
Packaging & Storage
The product is packaged in amber glass bottles with screw caps, placed in moisture-proof containers with desiccants. Storage conditions require cool and dry environment, away from direct sunlight and heat sources. Recommended storage temperature is 2-8°C for long-term stability. The product should be kept tightly sealed when not in use. Handling requires appropriate personal protective equipment including gloves, goggles, and lab coat in accordance with standard laboratory safety procedures.
—— C ompany Profile ——
Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.
Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.
We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.
To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.
Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.
—— Q&A ——
Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.
Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.
Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.