 Home > Encyclopedia > Simfibrate

Simfibrate

Simfibrate structure

CAS No:
14929-11-4
Formula:
C23H26Cl2O6
Chemical Name:
Simfibrate
Synonyms:
Propanoic acid,2-(4-chlorophenoxy)-2-methyl-,1,1′-(1,3-propanediyl) ester;Propionic acid,2-(p-chlorophenoxy)-2-methyl-,trimethylene ester;Propanoic acid,2-(4-chlorophenoxy)-2-methyl-,1,3-propanediyl ester;1,3-Propanediol,bis[2-(p-chlorophenoxy)-2-methylpropionate];1,3-Propanediol bis(2-p-chlorophenoxyisobutyrate);1,3-Propanediyl bis(α-p-chlorophenoxyisobutyrate);CLY 503;Simfibrate;1,3-Propane bis(2-p-chlorophenoxy-2-methylpropanoate);2-(p-Chlorphenoxy)-2-methylpropionic acid trimethylene ester;1,3-Propanediol bis[α-(chlorophenoxy)isobutyrate];Cholesolvin;Clofibric acid trimethylene ester;Diclofibrate;108913-91-3
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Request for Quotation

Description

Simfibrate is an organic molecular entity.|Simfibrate is a derivative of clofibrate with antilipidemic activity.

Simfibrate Basic Attributes

Molecular Weight：

469.358

Exact Mass：

469.35

EC Number：

238-998-7

UNII：

L2R75RQX26

DSSTox ID：

DTXSID8057647

NCI Thesaurus Code：

C72998

ATC Code：

C - Cardiovascular system

HScode：

2918990090

Characteristics

PSA：

71.1

XLogP3：

5.48490

Density：

1.2623 (estimate)

Melting Point：

52 °C

Boiling Point：

225 °C

Flash Point：

178.3ºC

Refractive Index：

1.541

Toxicity：

LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan)

Drug Information

MeSH Entry Terms：

1,3-propanediol bis(alpha-p-chlorophenoxyisobutyrate)

Computed Properties

Molecular Weight:469.4
XLogP3:6.2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:468.1106439
Monoisotopic Mass:468.1106439
Topological Polar Surface Area:71.1
Heavy Atom Count:31
Complexity:529
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Unspecified

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Double Bette
Manufacturer	China Resources Double-Crane Pharmaceutical Co., Ltd.

Registered Holders

China Resources Double-Crane Pharmaceutical Co., Ltd.

China
Active