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L-Valine

L-Valine structure

L-Valine 

structure
  • CAS No:

    72-18-4

  • Formula:

    C5H11NO2

  • Chemical Name:

    L-Valine

  • Synonyms:

    (S)-alpha-Aminoisovaleric acid, (L)-2-Amino-3-methylbutanoic acid;Valine (V) Solution, 100ppm;L-VALINE (13C5, 99%);L-Valine Vetec(TM) reagent grade, >=98%;(s)-2-amino-3-methylbutanoicacid;(S)-2-Amino-3-methylbutansαure;(s)-2-amino-3-methylbutyricacid;(s)-alpha-amino-beta-methylbutyricacid

  • Categories:

    Biochemical Engineering  >  Amino Acids and Proteins

Description

Valine (abbreviated as Val or V) is an α-amino acid with the chemical formula HO2CCH(NH2)CH(CH3)2. L-Valine is one of 20 proteinogenic amino acids. Its codons are GUU, GUC, GUA, and GUG. This essential amino acid is classified as nonpolar. Human dietary sources are any proteinaceous foods such as meats, dairy products, soy products, beans and legumes.Along with leucine and isoleucine, valine is a branched-chain amino acid. It is named after the plant valerian. In sickle-cell disease, valine substitutes for the hydrophilic amino acid glutamic acid in hemoglobin. Because valine is hydrophobic, the hemoglobin is prone to abnormal aggregation.


White or almost white, crystalline powder or colourless crystals, soluble in water, very slightly soluble in alcohol.


ChEBI: The L-enantiomer of valine.


Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA), maintains a balance among the BCAAs. L-Valine serves as an energy fuel.


Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

L-Valine Basic Attributes

117.15

1721136

200-773-6

TSCA listed

White

29224995

Characteristics

λ: 260 nm Amax: 0.15λ: 280 nm Amax: 0.1

1.23

295-300 °C (subl.) (lit.)

213.6±23.0 °C(Predicted)

28 ° (C=8, HCl)

85 g/L (20 ºC)

LD50 intraperitoneal in rat: 5390mg/kg

odorless

5.5-6.5 (100g/l, H2O, 20℃)

2.29(at 25℃)

2-8°C

Safety Information

3

Xn

24/25-36-22

YV9361000

40

L-Valine Use and Manufacturing

Amino acids drugs, nutritional supplements. It can be used as the main component of aminophenol transfusion and synthesize aminophenol. L-Valine is one of the three branched-chain amino acids. It is essential amino acid. It can be used to treat liver failure and central nervous system dysfunction.L-Valine is essential amino acid. The requirement for men is 10mg/(kg·d). Physiological effects of the L-form is 2 times of the D-type. L-Valine deficiency can cause neurological disorders, blastocolysis, loss of weight, anemia and the like. As nutritional supplements, it can be used to prepare aminophenol transfusion and synthesize aminophenol with other essential amino acid infusion. Valine added to metric pastry (1g/kg) can make the products aroma of sesame. L-Valine used in bread can also improve the flavor.L-Valine is the essential amino acid. It can be used as one of pharmaceutical composition of amino acid infusion to synthesize drugs. It also can be used as food additives.Nutritional supplements. It can be used to prepare aminophenol transfusion and synthesize aminophenol with other essential amino acid infusion.Valine added to metric pastry (1g/kg) can make the products aroma of sesame. L-Valine used in bread can also improve the flavor.L-Valine can be used for biochemical research, the preparation of tissue culture media. It also used as amino acids nutritional drugs in medicine.


L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.


valine is an amino acid used as a skin-conditioning and odor-masking agent. It is more commonly used in hair care preparations than in skin care.

Drug Function and Efficacy

Branched-chain amino acid contributing to skin repair and maintenance

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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