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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 740 qualified manufacturers and 374 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4830 Active Pharmaceutical Ingredients items

Poly(dimethylsiloxane)

CAS No: 9016-00-6

Formula: (C2H6OSi)n

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

colourless liquid with a viscosity, The polydimethylsiloxane materials are excellent examples of silicones because of their chemical properties and widespread industrial use. They can be manufactured as gels, resins, fluids, or elastomers, depending on the cross-linking characteristics. Toxicity testing using polydimethylsiloxane compounds on animals has found little, if any, harmful effects associated with chronic exposure. These tests include oral dosing and teratogenicity testing (Cutler et More

Cetirizine

CAS No: 83881-51-0

Formula: C21H25ClN2O3

Categories: Active Pharmaceutical Ingredients > Antiallergic Drugs

Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. IC50 value:Target: Histamine H1 receptorCetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. foundMore

Gemcitabine hydrochloride

CAS No: 122111-03-9

Formula: C9H11F2N3O4.ClH

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

Suitable for the treatment of inoperable advanced or metastatic pancreatic cancer and the treatment of locally advanced or metastatic non-small cell lung cancer, the treatment of intermediate and advanced non-small cell lung cancer, non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer and Other solid tumors.More

Dextran

CAS No: 9004-54-0

Categories: Active Pharmaceutical Ingredients > Viscosity Controlling

Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.More

Dasatinib

CAS No: 302962-49-8

Formula: C22H26ClN7O2S

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

Dasatinib (BMS-354825) is a dual Bcr-Abl and Src family tyrosine kinase inhibitor with IC50s of 0.6, 0.8, 79 and 37 nM for Abl, Src, c-Kit and c-KitD816V, respectively. More

Aripiprazole

CAS No: 129722-12-9

Formula: C23H27Cl2N3O2

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Colourless Flake Crystalline SolidAripiprazole was launched for the treatment of psychoses including schizophrenia and offers a novel mechanism of action as a partial D2 receptor agonist. Aripiprazole can be synthesized in three steps beginning by the condensation of 7-hydroxy-1,2,3,4-tetrahydroquinolin-2-one with 1 ,Cdibromobutane followed by reaction with 1-(2,3-dichlorophenyl)piperazine. Aripiprazole is a significant D2 agonist/antagonist, 5-HT2 antagonis.More

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Loratadine

CAS No: 79794-75-5

Formula: C22H23ClN2O2

Categories: Active Pharmaceutical Ingredients > Antiallergic Drugs

Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.IC50 value: 32 uMTarget: H1-receptorLoratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.More

Amlodipine Besylate

CAS No: 111470-99-6

Formula: C20H25ClN2O5.C6H6O3S

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

White Crystalline SolidChEBI: The benzenesulfonate salt of amlodipine.Amlodipine (generic name Amlodipine Besylate) is a class of calcium channel blockers. One of the amlodipine product on the market is Norvasc®.Amlodipine functionalizes by the dilation of blood vessels and the improvement of blood flow, which lead to lowered blood pressure. Thereby, it is used to treat high bold pressure (hypertension).More

Praziquantel

CAS No: 55268-74-1

Formula: C19H24N2O2

Categories: Active Pharmaceutical Ingredients > Antiparasitic Drugs

It is white or almost white crystalline powder; it is odorless with a slightly bitter taste. It also has hygroscopic effect. Solubility (g/100m1): 9.7 in ethanol, 56.7 in chloroform, and 0.04 in water. It is easily soluble in dimethyl sulfoxide (DMSO), but insoluble in ether. It has a melting point of 136~141 ℃. Acute toxicity LD50 in mice and rats (mg/kg): 2000~3000 oral administration,> 3,000 subcutaneously injection. White SolidMore

Metformin

CAS No: 657-24-9

Formula: C4H11N5

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Metformin (1,1-Dimethylbiguanide) inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin can cross the blood-brain barrier and triggers autophagy[1]. More

Gentamicin sulfate

CAS No: 1405-41-0

Formula: H2O4S.xUnspecified

Categories: Active Pharmaceutical Ingredients > Antibiotics

Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of 0.57 mM. More

Clobetasol propionate

CAS No: 25122-46-7

Formula: C25H32ClFO5

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Clobetasol propionate is a anti-inflammatory corticosteroid used to treat various skin disorders.Target: Glucocorticoid ReceptorClobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shamMore

Eucalyptus oil

CAS No: 8000-48-4

Formula:

Categories: Active Pharmaceutical Ingredients > Perfuming

E. globulus oil is produced by steam distillation of the leaves of E. globulus Labill. It is an almost colorless to pale yellow liquid with a fresh odor, characteristic of cineole.Thecrude oil contains more than 60% 1,8-cineole and between 10% and 22% α-pinene. Rectified qualities have a cineole content of more than 70 % or more than 80%. The respective specifications of these three types are as follows:
d
20
20
0.905–0.925/0.904–0.920/0.906–0.920; n
20
D
1.457–1.More

(±)-Atropine

CAS No: 51-55-8

Formula: C17H23NO3

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery. More

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

    40.0Yuan/kg -

Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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