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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 743 qualified manufacturers and 379 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4831 Active Pharmaceutical Ingredients items

Moxifloxacin

CAS No: 151096-09-2

Formula: C21H24FN3O4

Categories: Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent developed by Bayer AG (initially called BAY 12-8039), used to treat a number of infections, including: respiratory tract infections, cellulitis, anthrax, intraabdominal infections, endocarditis, meningitis, and tuberculosis. It is marketed worldwide (as the hydrochloride) under the brand names Avelox, Avalox, and Avelon for oral treatment. In most countries, the drug is also available in parenteral form for intravMore

(-)-Atropine

CAS No: 101-31-5

Formula: C17H23NO3

Categories: Active Pharmaceutical Ingredients > Digestive System Drugs

White to Off-White SolidChEBI: An atropine with a 2S-configuration. Hyoscyamine is a levorotatory alkaloidobtained from various solanaceous species. One ofthe commercial sources is Egyptian henbane (Hyoscyamusmuticus), in which it occurs to the extent of about 0.5%. Usually, it is prepared from the crude drug in a manner similarto that used for atropine and is purified as the oxalate. The free base is obtained easily from this salt. It occurs as white needles that are sparingly soluble in water.More

Rapamycin

CAS No: 53123-88-9

Formula: C51H79NO13

Categories: Active Pharmaceutical Ingredients > Drugs Influencing Immune Function

Rapamycin (Sirolimus) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM. More

Fludarabine

CAS No: 21679-14-1

Formula: C10H12FN5O4

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

Fludarabine(NSC 118218), a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment of hematological malignancies.Target:Fludarabine or fludarabine ph osphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas). It is a purine analog, which interferes with DNA synthesis. Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates thaMore

N-Methyl-D-glucamine

CAS No: 6284-40-8

Formula: C7H17NO5

Categories: Active Pharmaceutical Ingredients > Hair Conditioning

Meglumine is an amino sugar derived from sorbitol.Target: OthersMeglumine is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine and iodipamide meglumine.[1]More

Retinol

CAS No: 68-26-8

Formula: C20H30O

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

Retinol, also known as Vitamin A1, has pleiotropic functions including vison, immunity, hematopoiesis, reproduction, cell differentiation/growth, and development. More

Adefovir

CAS No: 106941-25-7

Formula: C8H12N5O4P

Categories: Active Pharmaceutical Ingredients > Phosphines

Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses[1][2][3]. More

Tripotassium citrate

CAS No: 866-84-2

Formula: C6H8O7.3K

Categories: Active Pharmaceutical Ingredients > Buffering

Colorless crystals or white crystalline powder, odorless, cool and salty, slight deliquescence, soluble in water and glycerin, insoluble in ethanol. Tests show that the product had no significant harm to the human body, ADI doesn’t need special provision (FAO/WHO, 1994). More

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Citalopram

CAS No: 59729-33-8

Formula: C20H21FN2O

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

ChEBI: A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.More

Ofloxacin

CAS No: 82419-36-1

Formula: C18H20FN3O4

Categories: Active Pharmaceutical Ingredients > Inhibitor Drugs

Ofloxacin is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.Target: DNA gyrase Ofloxacin is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. In vitro it has a broad spectrum of activity against aerobic Gram-negative and Gram-positive bacteria, although it is poorly active against anaerobes [1]. Ofloxacin, like other 4-quinolones, is unusual among front line drugs available to treat bacterial infections sMore

Potassium bromide

CAS No: 7758-02-3

Formula: BrK

Categories: Active Pharmaceutical Ingredients > Viscosity Controlling

White, crystalline granules or pow-der; pungent, strong, bitter, saline taste; somewhathygroscopic.Solu-ble in water and glycerol; slightly soluble in alcoholand ether.More

Rivaroxaban

CAS No: 366789-02-8

Formula: C19H18ClN3O5S

Categories: Active Pharmaceutical Ingredients > Blood System Drugs

Rivaroxaban is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM).More

Irbesartan

CAS No: 138402-11-6

Formula: C25H28N6O

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

Crystalline SolidChEBI: A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.Avapro was launched in Germany, the UK and the US for hypertension. It can be prepared in six steps starting with cyclopentanone or in three steps from 1- aminocyclopentanecarboxylic acid ethyl ester and pentanimidic ethyl ester. It is as potent as saralasin but with no agonist activity and is 10 times more potent than DuP753 in rats. It is similar in efMore

Clotrimazole

CAS No: 23593-75-1

Formula: C22H17ClN2

Categories: Active Pharmaceutical Ingredients > Anti-seborrheic

Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, suchMore

Tocopherol

CAS No: 1406-18-4

Formula: C29H50O2

Categories: Active Pharmaceutical Ingredients > Antioxidant Ingredient

Viscous oils. Soluble in fats; insoluble in water. Stable to heat in the absence of oxygen, to strong acids, and to visible light; unstable to UV light, alkalies, and oxidation.(vitamin E). Any of a group of related substances (α-, β-, γ-, andΔ-tocopherol) that constitute vitamin E. The α-form (which occurs naturally as the d-isomer) is the most potent. Occurs naturally in plants, especially wheat germ. All are derivatives of dihydrobenzo-γ-pyran and differ from each other only in the numberMore

Cetirizine

CAS No: 83881-51-0

Formula: C21H25ClN2O3

Categories: Active Pharmaceutical Ingredients > Antiallergic Drugs

Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. IC50 value:Target: Histamine H1 receptorCetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. foundMore

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

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Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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