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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 743 qualified manufacturers and 379 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4831 Active Pharmaceutical Ingredients items

Dutasteride

CAS No: 164656-23-9

Formula: C27H30F6N2O2

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Dutasteride is well tolerated and the most occurring adverse events are impotence, decrease in libido, ejaculation disorders and gynaecomastia. Unlike a-blockers which primarily act acutely on benign prostatic hyperplasia symptoms, 5a-reductase inhibitors can alter disease progression. Concomitant administration of dutasteride did not affect the pharmacokinetics of either tamsulosin or terazosin. In addition, the tolerability of both terazosin and tamsulosin were improved during combinatiMore

Thymol

CAS No: 89-83-8

Formula: C10H14O

Categories: Active Pharmaceutical Ingredients > Oral Care

Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects[1]. More

Ursodeoxycholic acid

CAS No: 128-13-2

Formula: C24H40O4

Categories: Active Pharmaceutical Ingredients > Skin Protecting

Ursodiol reduces cholesterol absorption and is used to dissolve gallstones.Target: OthersUrsodiol, also known as ursodeoxycholic acid and the abbreviation UDCA, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. The drug is very expensive, however, and if the patient stops taking it, the gallstones tend to recur iMore

Ezetimibe

CAS No: 163222-33-1

Formula: C24H21F2NO3

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

White SolidEzetimibe is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors.Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion.It takes effect throughactinMore

Glycyrrhizic acid

CAS No: 1405-86-3

Formula: C42H62O16

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.More

Piroxicam

CAS No: 36322-90-4

Formula: C15H13N3O4S

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively. More

Aminophylline

CAS No: 317-34-0

Formula: C7H8N4O2.1/2C2H8N2

Categories: Active Pharmaceutical Ingredients > Respiratory Drugs

Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD.Target: PhosphodiesteraseAminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthmaMore

Ascorbate

CAS No: 299-36-5

Formula: C6H7O6

Categories: Active Pharmaceutical Ingredients > Antibiotics

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Quetiapine

CAS No: 111974-69-7

Formula: C21H25N3O2S

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Quetiapine, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol fumarate (2:1,salt) (Seroquel), is a white to off-white crystalline powderthat is moderately water soluble. Quetiapine is rapidly absorbed,and peak plasma levels occur 1 to 2 hours after administration.Food does not appreciably affect the absorptionof quetiapine. The compound is 83% bound to plasma proteinsand it has a mean elimination half-life of 7 hours.Administration of a single dose of 14C-quetiapine showedtMore

Berberine hydrochloride

CAS No: 633-65-8

Formula: C20H18NO4.Cl

Categories: Active Pharmaceutical Ingredients > Plant Extracts

Berberine has shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells; MAPK and Wnt/β-catenin pathways affected by Berberine.IC50 value:Target: Anticancer agentThe plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecuMore

Colistin sulfate

CAS No: 1264-72-8

Formula: H2O4S.xUnspecified

Categories: Active Pharmaceutical Ingredients > Antibiotics

Colistin is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. More

(6R,7R)

CAS No: 155723-02-7

Formula: C13H13N3O3S2

Categories: Active Pharmaceutical Ingredients > Antibiotics

Intermediate in the preparation of Cephalosporin antibiotics and derivatives.More

Sulfadiazine

CAS No: 68-35-9

Formula: C10H10N4O2S

Categories: Active Pharmaceutical Ingredients > Amides

Sulfadiazine is a sulfonamide antibiotic.Target: AntibacterialSulfadiazine eliminates bacteria that cause infections by stopping the production of folate inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs). In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii. From Wikipedia.The ulcers who treated with silver sulfadiazine cream responded rapidly, with one-third showing bacterial leveMore

(±)-Chlorpheniramine

CAS No: 132-22-9

Formula: C16H19ClN2

Categories: Active Pharmaceutical Ingredients > Other Chemical Drugs

BPMore

Isosorbide

CAS No: 652-67-5

Formula: C6H10O4

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

Isosorbide is used as a diuretic used mainly to treat hydrocephalus and is also used to treat glaucoma. More

Hydroxycamptothecin

CAS No: 19685-09-7

Formula: C20H16N2O5

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

(S)-10-Hydroxycamptothecin is a clinical therapy agent against hepatoma.IC50 value:Target:In vitro: In vitro, the 10-hydroxycamptothecin nanosuspensions released the encapsulated drug with nearly zero-order kinetics, and the accumulative release reached 90% within 72 hours. In vitro cytotoxicity assay showed that the 10-hydroxycamptothecin nanosuspensions had significantly enhanced cytotoxicity against HepG2 cells compared to the commercially available 10-hydroxycamptothecin injections [More

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

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Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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