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Natural Products

Natural products refer to the constituents or metabolites of animals, plant or insects extracts, marine organisms, microorganisms, as well as many endogenous chemical components in humans and animals, of which include proteins, peptides, amino acids, nucleic acids, various enzymes, monosaccharides, oligosaccharides, polysaccharides, glycoproteins, resins, colloids, lignin, vitamins, fats, fats, waxes, alkaloids, volatile oils, flavonoids, glycosides, Terpenes, phenylpropanoids, organic acids, phenols, quinones, lactones, steroids, tannic acids, antibiotics and other chemical components in nature. Natural products are widely used in various industries, like pharmaceuticals, cosmetics, food, and agriculture, as they are considered healthy and versatile. ECHEMI is a leading B2B platform for global chemical products wholesale trade, including natural chemical products. Here you can easily connect with 1738 qualified natural products suppliers and companies for your natural hair products, natural cleaning products, natural skin care products, natural slim products, natural beauty products, natural baby products, etc.

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Sourcing natural chemical products is easy with ECHEMI. Connect with 56 trusted manufacturers and verified distributors providing a wide range of natural products, including plant extracts, bio-based materials, and other organic compounds for research, industrial, and commercial applications. Get high-quality natural chemicals and request competitive quotes from reliable suppliers.
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3060 Natural Products items

Sanguinarine

CAS No: 2447-54-3

Formula: C20H14NO4

Categories: Natural Products > Alkaloids

Sanguinarine, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB. More

Galangin

CAS No: 548-83-4

Formula: C15H10O5

Categories: Natural Products > Skin Protecting

Galangin is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity. More

Abietic acid

CAS No: 514-10-3

Formula: C20H30O2

Categories: Natural Products > Emulsifying Agent

Abietic Acid, also known as Abietic Acid or lignin acid, is a diterpenoid compound mainly derived from racemose capsicum. This compound has attracted much attention due to its unique anti-proliferation, antibacterial and anti-obesity properties. Abietic Acid has a wide range of potential applications in the medical field, especially in the treatment of allergies, where it can inhibit the activity of lipoxygenase, thereby exerting its therapeutic effect. Abietic Acid is found in a wide variety of trees, especially pine and resin. It is the main component of resinous acid and one of the main irritants in pine and resin. Abietic Acid can be separated from the rosin through an isomerization process. Rosin is the solid part of conifer oil resin, and Abietic Acid is the most abundant of several closely related organic acids that make up rosin. The esters or salts of Abietic Acid are called benzoates, and these compounds also have important applications in the chemical industry. Abietic Acid usually appears as a pale yellow resin powder with a distinctive odor. Its physical form can be liquid, dry powder, particles or large crystals and other forms. Light yellow to amber colored fragments or powders are a common appearance of Abietic Acid, and these forms have different use values in different applications. Abietic acid, another abietane diterpenoid, is formed by the substitution of abiet-7, 13-diene with a carboxyl group at position 18. Abietic acid plays an important role in plant metabolism and is a bioactive compound. It is not only a abietane diterpene, but also a monocarboxylic acid. Abietic acid, as the conjugated acid of pinic acid ester, also has certain application value in chemical reaction.More

(-)-Parthenolide

CAS No: 20554-84-1

Formula: C15H20O3

Categories: Natural Products > Skin Conditioning

Parthenolide is an NF-κB inhibitor, reduces histone deacetylase 1 (HDAC-1) and DNA methyltransferase 1 independent of NF-κB inhibition. More

Quercitrin

CAS No: 522-12-3

Formula: C21H20O11

Categories: Natural Products > Flavonoids

Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions.IC50 value:Target:In vitro: There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. [1] In vivo: ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration forMore

Quercetin 3-glucoside

CAS No: 482-35-9

Formula: C21H20O12

Categories: Natural Products > Antioxidant Ingredient

Quercetin-3-glucoside is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties.Quercetin-3-glucoside alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway[1].Quercetin-3-glucoside regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Quercetin-3-glucoside has high bioavailabMore

Hederagenin

CAS No: 465-99-6

Formula: C30H48O4

Categories: Natural Products > Terpenes

Hederagenin is a triterpenoid saponin. It can inhibit LPS-stimulated expression of iNOS, COX-2, and NF-κBHederagenin can Exhibits multiple pharmacological activities in the treatment of hyperlipidemia, antilipid peroxidation, antiplatelet aggregation, liver protection, antidepression, anti-inflammation.[1]In vitro:1) Hederagenin can correct the imbalance of endothelial function by inhibiting the release of large amounts of iNOS and increasing eNOS contents and inhibits the IKKβ/NF-κB sigMore

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2,2,6,6-Tetramethyl-4-piperidone

CAS No: 826-36-8

Formula: C9H17NO

Categories: Natural Products > Alkaloids

Triacetonamine is useful as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine is an artifact of plant and fungal extracts using acetone and ammonium hydroxide or natural occurrence of ammonium salts in various steps of the isolation procedures. TAA is the main component of the pyrolysis oil[1].More

Piceatannol

CAS No: 10083-24-6

Formula: C14H12O4

Categories: Natural Products > Antioxidant Ingredient

Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects.In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppreMore

Baccatin III

CAS No: 27548-93-2

Formula: C31H38O11

Categories: Natural Products > Terpenes

Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs[1].More

Hesperidin methylchalcone

CAS No: 24292-52-2

Formula: C29H36O15

Categories: Natural Products > Antioxidant Ingredient

Hesperidin methylchalcone (Hesperidin methyl chalcone) inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone inhibits inflammation and pain. Hesperidin methylchalcone exhibits vasoprotective activity[1]. More

Acacetin

CAS No: 480-44-4

Formula: C16H12O5

Categories: Natural Products > Flavonoids

1) Natural acacetin was a 4.0-fold and 5.5-fold more potent inhibitor of BACE-1 than oleanolic acid and maslinic acid, respectively.[1]2) Acacetin significantly suppressed the photoreceptor collapse. [1]3) Acacetin significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression. [1]4) Acacetin inhibited the generation of the APP-CTF by affecting APP cleavage. [1]5) Acacetin prolongs lifespan of significantly in the dose dependent manner. AcaMore

Amentoflavone

CAS No: 1617-53-4

Formula: C30H18O10

Categories: Natural Products > Bleaching Agent

Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects.IC50 value:Target:In vitro: In irradiated v79 cells, Pretreatment with amentoflavone 24 hours prior to 8 Gy 60Co γ-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass [2]. Amentoflavone dose-dependently inhibited the viability of SW480 cells, and a high concentMore

Gramine

CAS No: 87-52-5

Formula: C11H14N2

Categories: Natural Products > Alkaloids

Gramine (Donaxine) is a natural alkaloid isolated from giant reed[2], acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 µM for AdipoR2 and AdipoR1, respectively[1]. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist[2]. Gramine (Donaxine) has anti-tumor, anti-viral and anti-inflammatory properties[1]. More

(-)-Vindoline

CAS No: 2182-14-1

Formula: C25H32N2O6

Categories: Natural Products > Alkaloids

Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly[1].More

Frequently Asked Questions

What are natural products commonly used for in industry?

Natural products are widely used in pharmaceuticals, nutraceuticals, cosmetics, food and beverage, agricultural chemicals, and biotechnology. They are valued for their bioactivity, sustainability, and functional properties such as antioxidant, anti-inflammatory, antimicrobial, or aromatic effects. Many companies source natural compounds as active ingredients, intermediates, or additives in modern formulations.

Are natural chemicals always safe?

No, natural chemicals are not always safe. While many people associate “natural” with “safe,” some naturally occurring substances can be highly toxic or harmful. For example, mercury is a naturally occurring element, yet it is dangerous to human health even in small amounts.

In fact, very few substances are completely safe under all conditions. Even common natural products like water can be harmful if consumed in excessive quantities. Safety always depends on the type of substance, concentration, exposure level, and usage method, rather than whether it comes from a natural or synthetic source.

Are chemicals always synthetic, or can they be natural?

Chemicals can be either natural or synthetic. A natural chemical is a substance that occurs in nature without human intervention, such as water (H₂O), sodium chloride, or natural plant compounds like caffeine and menthol. Synthetic chemicals, on the other hand, are produced through industrial or laboratory processes.

Therefore, when discussing “chemicals” in general, the term includes both naturally occurring and man-made substances. The key difference lies in the source and the method of production, not in whether a substance is considered a “chemical.”

What are examples of natural products?

Natural products are organic or inorganic substances produced by living organisms or found in nature without industrial synthesis. Common examples include plant extracts, alkaloids, flavonoids, terpenes, phenols, steroids, lignans, and coumarins. Natural materials such as wood, silk, resins, essential oils, milk, soil, and coal are also considered natural products.

On ECHEMI, natural products are categorized into groups such as Lignans, Xanthones, Flavonoids, Terpenes, Iridoids, Coumarins, Phenols, Steroids, Phenylpropanoids, Anthraquinones, Chalcones, Alkaloids, Quinone Ring compounds, and Sesquiterpenes. You can easily browse these categories and connect with reliable wholesale natural products suppliers or request a quote based on your specific needs.

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