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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 743 qualified manufacturers and 379 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4831 Active Pharmaceutical Ingredients items

Maduramycin

CAS No: 61991-54-6

Formula: C28H20O11

Categories: Active Pharmaceutical Ingredients > Antiparasitic Drugs

Mevastatin

CAS No: 73573-88-3

Formula: C23H34O5

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. IC50 value: 1 nM (Ki)Target: HMGCRMevastatin induces apoptosis, arrests cancer cells in G1 phase and downregulates cdk 2, 4, and 6, cyclin D1 and E1, p21 and p27. Mevastatin suppresses TNF-induced NF-κB activation (IC50 = ~17 uM), which potentiates apoptosisMore

Quinine sulfate dihydrate

CAS No: 6119-70-6

Formula: C20H24N2O2.1/2H2O4S.2H2O

Categories: Active Pharmaceutical Ingredients > Antiparasitic Drugs

White or almost white, crystalline powder or fine, colourless needles. Quinine sulfate is odorless and has a persistent, very bitter taste. It darkens on exposure to light. Its saturated solution is neutral or alkaline to litmus.More

Dequalinium chloride

CAS No: 522-51-0

Formula: C30H40N4.2Cl

Categories: Active Pharmaceutical Ingredients > Antiplaque

Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels.Target: Potassium ChannelDequalinium Chloride is a selective blocker of apamin-sensitive K+ channels. Treatment with Dequalinium chloride did not influence conditions caused by haemolytic streptococci -- verified by bacteriological examinations of pharyngeal smears -- inspite of its efficiency in vitro [1]. Dequalinium chloride (DECA), a cationic, lipophilic mitochondrial poison, selectively targets the mitochondMore

Betahistine dihydrochloride

CAS No: 5579-84-0

Formula: C8H12N2.2ClH

Categories: Active Pharmaceutical Ingredients > Circulatory System Drugs

Betahistine Dihydrochloride is a histamine H3 receptors inhibitor used as an antivertigo drug.Target: Histamine ReceptorBetahistine, a structural analogue of histamine with weak histamine H(1) receptor agonist and more potent H(3) receptor antagonist properties. Betahistine acts centrally by enhancing histamine synthesis within tuberomammillary nuclei of the posterior hypothalamus and histamine release within vestibular nuclei through antagonism of H(3) autoreceptors [1].Therapeutic effeMore

Pemirolast potassium

CAS No: 100299-08-9

Formula: C10H8N6O.K

Categories: Active Pharmaceutical Ingredients > Antiallergic Drugs

Crystalline SolidPemirolast potassium is a new potent antiallergic mast cell stabilizer with a similarmechanism to sodium cromoglycate. Its main indication is bronchial asthma. Anotherindication under investigation is as a gastroprotective agent.Pemirolast potassium, 9-methyl-3-(1H-tetrazol-5-yl)-4Hpyrido[1, 2- ]pyrimidin-4-one potassium (Alamast), is ayellow, water-soluble powder. It can be considered an analogof one portion of the cromolyn structure in which thecarboxyl group has been repMore

Entecavir intermediate N5

CAS No: 142217-78-5

Formula: C52H49N5O5

Categories: Active Pharmaceutical Ingredients > Other Chemical Drugs

1122 Active Pharmaceutical Ingredients Suppliers

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Penicillin V

CAS No: 87-08-1

Formula: C16H18N2O5S

Categories: Active Pharmaceutical Ingredients > Antibiotics

Crystalline SolidMore

actinomycin D

CAS No: 50-76-0

Formula: C62 H86 N12 O16

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

Actinomycin D inhibits DNA repair with an IC50 of 0.42 μM. More

Benzydamine

CAS No: 642-72-8

Formula: C19H23N3O

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Used as an anti-inflammatory analgesicMore

Sitafloxacin

CAS No: 127254-12-0

Formula: C19H18ClF2N3O3

Categories: Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Sitafloxacin (Trade name: Gracevit in Japan) belongs to a new generation, broad-spectrum oral fluoroquinolone antibiotics. It is highly active against various kinds of gram-negative, gram-positive and anaerobic clinical isolates, even including strains that are resistant to other kinds of fluoroquinolone antibiotics. It has been listed in Japan for the treatment of respiratory and urinary tract infections. It also shows potential for the treatment of Buruli ulcer. Its mechanism of action is thrMore

Pilocarpine

CAS No: 92-13-7

Formula: C11H16N2O2

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Colorless crystalline solid or an oil; melts at34°C (93.2°F); dissolves in water, alcohol,and chloroform; slightly soluble in ether andbenzene.More

Alendronate sodium

CAS No: 129318-43-0

Formula: C4H13NO7P2.Na

Categories: Active Pharmaceutical Ingredients > Fluid, Electrolyte, and Acid-base Balance

Alendronate sodium is the fourth bisphosphonate to reach the market for the treatment of postmenopausal osteoporosis. Bisphosphonates are potent inhibitors of bone resorption. They reduce pain and complications due to bone metastases, are effective in Paget's disease and in increasing bone mineral density. These agents bind tightly to hydroxyapatite crystals and are retained on bone resorption surfaces. It has also been shown to reduce hypercalcemia in cancer patients.Alendronate sodium isMore

Febantel

CAS No: 58306-30-2

Formula: C20H22N4O6S

Categories: Active Pharmaceutical Ingredients > Antiparasitic Drugs

Febantel is an anthelmintic for veterinary use on dogs, cats, cattle, sheep, goats, pig and poultry against roundworms and tapeworms.Target: anthelmintic compoundFebantel is a veteran anthelmintic (wormer) compound belonging to the chemical class of the benzimidazoles, but is a so-called pro-benzimidazole, i.e. it is transformed into a benzimidazole once it gets into the host's organism. Febantel it is transformed into fenbendazole in the stomach and the intestine of the host, shortly afMore

(-)-Bergenin

CAS No: 477-90-7

Formula: C14H16O9

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

Bergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action. IC50 value: < 2.5 μM (antiplasmodial) [3]Target:In vitro: The naloxone-precipitated withdrawal symptom (jumping frequency) was significantly ameliorated (50% of control group) by administration of bergenin (20 mg/kg) in morphine-treated mice. Furthermore, morphine-induced down-regulation of glutathione (GSH) contents was reversed by bergenin administration in the frontal cortex and liver [2].In vivo: BergeninMore

Dithranol

CAS No: 1143-38-0

Formula: C14H10O3

Categories: Active Pharmaceutical Ingredients > Specialty Drugs

Yellow Crystalline SolidChEBI: An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9.Lemon yellow leaflets or plates or an orange powder. Melting point 176-181°C. No odor or taste. Insoluble in water. Moderately toxic by ingestion, inhalation and skin absorption. Used as a treatment for psoriasis.More

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

    40.0Yuan/kg -

Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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