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Natural Products

Natural products refer to the constituents or metabolites of animals, plant or insects extracts, marine organisms, microorganisms, as well as many endogenous chemical components in humans and animals, of which include proteins, peptides, amino acids, nucleic acids, various enzymes, monosaccharides, oligosaccharides, polysaccharides, glycoproteins, resins, colloids, lignin, vitamins, fats, fats, waxes, alkaloids, volatile oils, flavonoids, glycosides, Terpenes, phenylpropanoids, organic acids, phenols, quinones, lactones, steroids, tannic acids, antibiotics and other chemical components in nature. Natural products are widely used in various industries, like pharmaceuticals, cosmetics, food, and agriculture, as they are considered healthy and versatile. ECHEMI is a leading B2B platform for global chemical products wholesale trade, including natural chemical products. Here you can easily connect with 1738 qualified natural products suppliers and companies for your natural hair products, natural cleaning products, natural skin care products, natural slim products, natural beauty products, natural baby products, etc.

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Sourcing natural chemical products is easy with ECHEMI. Connect with 54 trusted manufacturers and verified distributors providing a wide range of natural products, including plant extracts, bio-based materials, and other organic compounds for research, industrial, and commercial applications. Get high-quality natural chemicals and request competitive quotes from reliable suppliers.
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3058 Natural Products items

(-)-Maackiain

CAS No: 2035-15-6

Formula: C16H12O5

Categories: Natural Products > Phenols

(-)-Maackiain is a pterocarpan phytoalexin produced from Red clover (Trifolium pretense L.). (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts[1]. More

Neobavaisoflavone

CAS No: 41060-15-5

Formula: C20H18O4

Categories: Natural Products > Flavonoids

Neobavaisoflavone, an isoflavone isolated from Psoralea corylifolia, has striking anti-inflammatory and anti-cancer effects. IC50 value: 42.93 μM (toward CCRF-CEM cells); 114.64 μM [against HCT116 (p53(+/+)) cells] [2]Target:In vitro: In the cancer cells, neobavaisoflavone sensitizes human U373MG glioma cells to TRAIL-mediated apoptosis; upregulated DR5 expression; induced TRAIL-mediated apoptosis in human glioma cells by suppressing migration and invasion, and by inhibiting anoikis resiMore

Glycoursodeoxycholic acid

CAS No: 64480-66-6

Formula: C26H43NO5

Categories: Natural Products > Steroids

Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.In Vitro: The antioxidant compound glycoursodeoxycholic acid (GUDCA) fully abrogates UCB-induced cytochrome c oxidase inhibition and significantly prevents oxidative stress, metabolic alterations, and cell demise[1].GUDCA has shown therapeutic efficacy in neurodegenerative models and diseases. Increased cytosolic SOD1 inclusions were observed in 4 DIV NSC-34/hSOD1(G93A) ceMore

Jaceosidin

CAS No: 18085-97-7

Formula: C17H14O7

Categories: Natural Products > Flavonoids

Jaceosidin is a flavonoid isolated from Artemisia vestita, induces apoptosis in cancer cells, activates Bax and down-regulates Mcl-1 and c-FLIP expression[1]. Jaceosidin exhibits anti-cancer[2], anti-inflammatory activities, decreases leves of inflammatory markers, and suppresses COX-2 expression and NF-κB activation[3]. More

(+)-Boldine

CAS No: 476-70-0

Formula: C19H21NO4

Categories: Natural Products > Alkaloids

Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1]. More

Kaempferol 3-O-rutinoside

CAS No: 17650-84-9

Formula: C27H30O15

Categories: Natural Products > Antioxidant Ingredient

Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Flos Carthami. Nicotiflorin shows potent antiglycation activity and neuroprotection effects. More

Koumine

CAS No: 1358-76-5

Formula: C20H22N2O

Categories: Natural Products > Alkaloids

Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells[1]. Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities[3], protects against the development of arthritis in Rheumatoid arthritis (RA) animal models[2]. More

(R)-Usnic acid

CAS No: 7562-61-0

Formula: C18H16O7

Categories: Natural Products > Phenols

(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. More

3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one

CAS No: 53947-92-5

Formula: C20H16O4

Categories: Natural Products > Flavonoids

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound.IC50 value:Target: in vitro: Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM [1]. More

trans-Nerolidol

CAS No: 40716-66-3

Formula: C15H26O

Categories: Natural Products > Perfuming

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Prunetin

CAS No: 552-59-0

Formula: C16H12O5

Categories: Natural Products > Flavonoids

Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor[1][2]. More

Isoxanthohumol

CAS No: 70872-29-6

Formula: C21H22O5

Categories: Natural Products > Flavonoids

(2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol[1]. More

Rhoifolin

CAS No: 17306-46-6

Formula: C27H30O14

Categories: Natural Products > Flavonoids

Rhoifolin is a flavone glycoside isolated from Citrus grandis (L.) Osbeck leaves. Rhoifolin is beneficial for diabetic complications through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation[1]. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways[2]. More

(+)-Betulonic acid

CAS No: 4481-62-3

Formula: C30H46O3

Categories: Natural Products > Terpenes

Betulonic acid belongs to the pentacyclic triterpenic derivative class, has antitumor activities.In vitro: BEA-NP is found over three-times more permeable than that solubilized by DMSO in Caco-2 cell monocultures.[1]In vivo: The tumor growth in the S180 berry mice orally doses with BEA-NP at 75 mg/kg is inhibited by 50%. Rubusoside is effective in solubilizing BEA, maintaining its cytotoxicity, enhancing its permeability and reducing tumor growth when orally administered.[1] antitumor acMore

2',4',6'-TRIMETHOXYACETOPHENONE

CAS No: 832-58-6

Formula: C11H14O4

Categories: Natural Products > Phenols

4,4'-DIHYDROXY-2-METHOXYCHALCONE

CAS No: 34221-41-5

Formula: C16H14O4

Categories: Natural Products > Chalcones

Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2]. More

Trifolirhizin

CAS No: 6807-83-6

Formula: C22H22O10

Categories: Natural Products > Phenols

Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM[1]. Trifolirhizin exhibits potential anti-inflammatory and anticancer activities[2]. More

Loganic acid

CAS No: 22255-40-9

Formula: C16H24O10

Categories: Natural Products > Iridoid Derivatives

Loganic acid is an iridoid isolated from cornelian cherry fruits. Loganic acid can modulate diet-induced atherosclerosis and redox status. Loganic acid has strong free radical scavenging activity and remarkable cyto-protective effect against heavy metal mediated toxicity[1][2]. More

Hinokiflavone

CAS No: 19202-36-9

Formula: C30H18O10

Categories: Natural Products > Flavonoids

ChEBI: A biflavonoid that is apigenin substituted by a 4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy group at position 6. A diflavonyl ether, it is isolated from Rhus succedanea and has been found to possess significant cytotoxic otential.More

Asperuloside

CAS No: 14259-45-1

Formula: C18H22O11

Categories: Natural Products > Iridoid Derivatives

ChEBI: A iridoid monoterpenoid glycoside isolated from Galium verum.More

Frequently Asked Questions

What are natural products commonly used for in industry?

Natural products are widely used in pharmaceuticals, nutraceuticals, cosmetics, food and beverage, agricultural chemicals, and biotechnology. They are valued for their bioactivity, sustainability, and functional properties such as antioxidant, anti-inflammatory, antimicrobial, or aromatic effects. Many companies source natural compounds as active ingredients, intermediates, or additives in modern formulations.

Are natural chemicals always safe?

No, natural chemicals are not always safe. While many people associate “natural” with “safe,” some naturally occurring substances can be highly toxic or harmful. For example, mercury is a naturally occurring element, yet it is dangerous to human health even in small amounts.

In fact, very few substances are completely safe under all conditions. Even common natural products like water can be harmful if consumed in excessive quantities. Safety always depends on the type of substance, concentration, exposure level, and usage method, rather than whether it comes from a natural or synthetic source.

Are chemicals always synthetic, or can they be natural?

Chemicals can be either natural or synthetic. A natural chemical is a substance that occurs in nature without human intervention, such as water (H₂O), sodium chloride, or natural plant compounds like caffeine and menthol. Synthetic chemicals, on the other hand, are produced through industrial or laboratory processes.

Therefore, when discussing “chemicals” in general, the term includes both naturally occurring and man-made substances. The key difference lies in the source and the method of production, not in whether a substance is considered a “chemical.”

What are examples of natural products?

Natural products are organic or inorganic substances produced by living organisms or found in nature without industrial synthesis. Common examples include plant extracts, alkaloids, flavonoids, terpenes, phenols, steroids, lignans, and coumarins. Natural materials such as wood, silk, resins, essential oils, milk, soil, and coal are also considered natural products.

On ECHEMI, natural products are categorized into groups such as Lignans, Xanthones, Flavonoids, Terpenes, Iridoids, Coumarins, Phenols, Steroids, Phenylpropanoids, Anthraquinones, Chalcones, Alkaloids, Quinone Ring compounds, and Sesquiterpenes. You can easily browse these categories and connect with reliable wholesale natural products suppliers or request a quote based on your specific needs.

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