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Methylcellulose

Methylcellulose structure

CAS No:
9004-67-5
Formula:
CH4O.xUnspecified
Chemical Name:
Methylcellulose
Synonyms:
Cellulose,methyl ether;Adulsin;Bagolax;Bufapto Methalose;Bulkaloid;Celacol M;Celacol MM;Cellapret;Cellogran;Cellothyl;Cellulose methylate;Cellumeth;Cethytin;Hydrolose;Mellose;Methocel 400CPS;Methocel 4000CPS;Methulose;Methocel 400;Methocel 10;Rhomellose;Syncelose;Tylose SAP;Tylose SL;Tylose TWA;Viscol;Viscosol;Tylose A 4S;Methylcellulose;Methocel MC;Methyl cellulose ether;SM 4000;Methocel MC 25;Methocel SM 100;Tylose 444;Methocel MC 4000;Celacol M 20;Walsroder MC 20000S;Cethylose;Nicel;Methocel A;Methocel MC 8000;Tylose MF;Celacol M 450;Celacol M 20P;MCO 8000;MC 20000S;Tylose SL 100;Tylose SL 400;Viscontran L 52;Celacol MM 10P;Tylose SL 600;Napolone;Marpolose 60SH50;Marpolose M 25;Metolose MC 8000;Methocel CHG;Metolose SM 4000;Metolose SM 100;MTs (cellulose derivative);Metolose SM 15;MC 4000cP;Culminal K 42;Edisol M;MMTs-BTR;Methylan SP;Culminal MC 2000;Culminal MC;Celacol M 2500;O-Methylcellulose;Marpolose M 10000;Marpolose 90MP30000;Methocel ST 65HG50;Methocel A 4C;Metolose SM 1500;Marpolose M 400;Marpolose EM 2000;Metolose SM 25;Marpolose 90MP10000;EMP-H;Celacol MMPR;Methocel A 15LV;Methoxycellulose;Viscontran MC 400;Metolose 4000;Walocel M;Methocel A 15C;Metolose SM 8000;SM 8000;Probe D;Methocel A 4M;Culminal MC 40;MC 40;Methocel A 50;Metolose SM;Viskontran MC 10S;Cesca C 8556;Methocel A 100;Methocel 4C;Culminal MC 6OS;Cesca MC 25S;Cesca MC 400;SM 15;SM 100000;39384-65-1;53568-34-6;71812-19-6;88402-84-0;99638-59-2;730985-58-7;2098627-58-6
Categories:
Cosmetic Ingredient > Emulsion Stabilising

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Description

Methylcellulose is a natural polymer which gels on heating. Methylcellulose is not toxic.

Methylcellulose Basic Attributes

Molecular Weight：

658.72900

Exact Mass：

658.34100

EC Number：

618-391-7

HScode：

39129000

Characteristics

PSA：

147.68000

XLogP3：

-0.37790

Appearance：

Methyl cellulose appears as odorless white or creamy white fibrous powder. Tasteless. (NTP, 1992)

Density：

1.01 g/cm³ @ Temp: 70 °C

Melting Point：

290-305 °C

Water Solubility：

soluble in cold water

Storage Conditions：

Methylcellulose powder is stable, although slightly hygroscopic. The bulk material should be stored in an airtight container in a cool, dry place.
Solutions of methylcellulose are stable to alkalis and dilute acids at pH 3–11, at room temperature. At pH less than 3, acid-catalyzed hydrolysis of the glucose–glucose linkages occurs and the viscosity of methylcellulose solutions is reduced.On heating, solution viscosity is reduced until gel formation occurs at approximately 50°C;
Methylc

Odor：

Odorless

Taste：

Tasteless

PH：

Aq suspensions neutral to litmus

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

S24/25

RTECS Number：

FJ5959000

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents, bleach, perchloric acid, nitric acid, perchlorates, alkali nitrates, alkali nitrites, calcium oxide.

Methylcellulose Use and Manufacturing

Thickener & suspending agent in latex paints, paintermediate remover, protective colloid in textile inks, vinyl chloride polymerization, binder, thickener in various building products, water retention agent in various building products, component of adhesives in pasting of hides during tanning, thickener & suspending agent in detergents, hard surface cleaners, additive in foods & pharmaceuticals.

Material

Propylene Oxide

Hydrochloric acid

Drug Function and Efficacy

Methylcellulose is widely used in various oral and topical formulations as a pharmaceutical excipient, serving as a binder and suspending agent. It has bulking laxative effects when administered orally in large amounts due to its high viscosity grade.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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FOSTER AND THRIVE FIBER LAXATIVE 188_- methylcellulose_tablet
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PEPTO-BISMOL- bismuth subsalicylate_suspension
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Registered Holders

NUTRITION & BIOSCIENCES USA 1 LLC

United States
Active
Taian Ruitai Cellul'ose Co., Ltd.

China
Active
Shandong Liaocheng E HUA Pharmaceutical Co., Ltd.

China
Active

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