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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 744 qualified manufacturers and 392 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4852 Active Pharmaceutical Ingredients items

Bimatoprost

CAS No: 155206-00-1

Formula: C25H37NO4

Categories: Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Crystalline SolidBimatoprost was first introduced in the US and Brazil as Lumigan, an ophthalmic solution (0.03%) for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension, a proven risk of glaucomatous visual field loss. Bitamoprost is a new agent belonging to the PGF2α analog class of prostamides launched in this indication after latanoprost, the most efficaceous topical medication currently available. More

Anethole

CAS No: 104-46-1

Formula: C10H12O

Categories: Active Pharmaceutical Ingredients > Denaturant

Anethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.More

Famotidine

CAS No: 76824-35-6

Formula: C8H15N7O2S3

Categories: Active Pharmaceutical Ingredients > Digestive System Drugs

Famotidine is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.Target: Histamine H2 ReceptorFamotidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and it is commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD/GORD). Famotidine Group(2 mg/kg/day) were significantly lower than the equivalent parameters for the Control Group on both the thMore

Dabigatran

CAS No: 211914-51-1

Formula: C25H25N7O3

Categories: Active Pharmaceutical Ingredients > Blood System Drugs

Dabigatran(BIB-953; BIBR 953ZW) is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.IC50 Value: 4.5 nM (Ki); 10 nM(Thrombin-induced platelet aggregation) [1]Target: thrombinin vitro: Dabigatran selectively and reversibly inhibited human thrombin(Ki: 4.5 nM) as well as thrombin-induced platelet aggregation (IC(50): 10 nM), while showing no inhibitory effect on other platelet-stimulating agents.Thrombin generation in platelet-poor plasma (PPP), measured aMore

Calcitonin

CAS No: 9007-12-9

Categories: Active Pharmaceutical Ingredients > Fluid, Electrolyte, and Acid-base Balance

Calcitonin is a single-chain polypeptide composed of 32 amino acid residues having a molecular weight of approximately 3600. A cysteine disulfide bridge at the 1-7 position of the amino terminal end of the peptide is essential for biological activity; however, the entire amino acid sequence is required for optimal activity.More

Piracetam

CAS No: 7491-74-9

Formula: C6H10N2O2

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

Piracetam is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.Target: OthersPiracetam is able to significantly decrease the fusogenic and destabilising effect of Abeta 29-42, in a concentration-dependent manner. Preincubation of piracetam, at a piracetam/peptide ratio of 960, during 20 min before the addition of Abeta 29-42 prevents almost completely the mixture of the two fluorescent probes. PreincubatioMore

Ampicillin trihydrate

CAS No: 7177-48-2

Formula: C16H19N3O4S.3H2O

Categories: Active Pharmaceutical Ingredients > Antibiotics

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. More

Oxazolidin

CAS No: 129-20-4

Formula: C19H20N2O3

Categories: Active Pharmaceutical Ingredients > Antipyretic Analgesics

Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2]. More

Agomelatine

CAS No: 138112-76-2

Formula: C15H17NO2

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). IC50 value: 6.2 (pKi, 5-HT2c); 6.6 (pKi, 5-HT2b)Target: 5-HT2C Receptor; 5-HT2B receptorIt is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results inMore

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Clindamycin phosphate

CAS No: 24729-96-2

Formula: C18H34ClN2O8PS

Categories: Active Pharmaceutical Ingredients > Antibiotics

Clindamycin phosphate is an antibiotic, which blocks the ribosomes of microorganisms. It is usually used to treat infections with anaerobic bacteria, can also be used to treat protozoal diseases, such as malaria. More

Gatifloxacin

CAS No: 112811-59-3

Formula: C19H22FN3O4

Categories: Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.Target: AntibacterialGatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Gatifloxacin had activity equal to that of tosufloxacin and activity more potent than those of norfloxacin, ofloxacin, ciprofloxacin, and sparfMore

Nifedipine

CAS No: 21829-25-4

Formula: C17H18N2O6

Categories: Active Pharmaceutical Ingredients > Antioxidant Ingredient

Yellow crystals. Melting point 172-174 ℃. Soluble in acetone, chloroform, ethyl acetate, dissolved in hot methanol, insoluble in water. It easily deteriorates in case of light. More

Carboplatin

CAS No: 41575-94-4

Formula: C6H12N2O4Pt

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of cisplatin and a potent anti-cancer agent. More

Risperidone

CAS No: 106266-06-2

Formula: C23H27FN4O2

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.More

Baclofen

CAS No: 1134-47-0

Formula: C10H12ClNO2

Categories: Active Pharmaceutical Ingredients > Anesthetic Agents

White powder. Melting point: 206-208 °C. Dissolve using hot water, the aqueous solution was neutral, almost insoluble in alcohol, ether, acetone and other organic solvents, easily soluble in acidic, alkaline aqueous solution. The melting point of Chlorobenzene aminobutyric acid hydrochloride: 179-181 °C. Off-White SolidChEBI: A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depMore

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
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Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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