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Home > Active Pharmaceutical Ingredients
In the chemical industry, API is Active Pharmaceutical Ingredients, meaning the active ingredients in pharmaceutical products. It is the core substance for producing the intended therapeutic effect. The quality of Active Pharmaceutical Ingredients is critical to the safety and efficacy of the final pharmaceutical product. Therefore, the production of API chemicals involves strict regulatory guidelines and standards, such as GMP (Good Manufacturing Practices) and GLP (Good Laboratory Practices). On ECHEMI, you can select API chemical products on your demand from various active pharmaceutical ingredient manufacturers and distributors.

Active Pharmaceutical Ingredients Suppliers

Buying Active Pharmaceutical Ingredients (APIs) can still be challenging, especially when quality, compliance, and supply stability matter most. On ECHEMI, you can access 741 qualified manufacturers and 356 verified distributors across China, India, the USA, Europe, and other regions. Compare API specifications, review compliance standards, and connect directly with reliable suppliers to support your pharmaceutical production and research needs.
Explore active pharmaceutical ingredients for your specific needs now.
4827 Active Pharmaceutical Ingredients items

(±)-Chloroquine diphosphate

CAS No: 50-63-5

Formula: C18H26ClN3.2H3O4P

Categories: Active Pharmaceutical Ingredients > Antiparasitic Drugs

Chloroquine (diphosphate) is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. Chloroquine is an inhibitor of autophagy and toll-like receptors (TLRs). More

Paeonol

CAS No: 552-41-0

Formula: C9H10O3

Categories: Active Pharmaceutical Ingredients > Antioxidant Ingredient

Paeonol is an active extraction from the root of Paeonia suffruticosa, Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. More

Roflumilast

CAS No: 162401-32-3

Formula: C17H14Cl2F2N2O3

Categories: Active Pharmaceutical Ingredients > Respiratory Drugs

Crystallin SolidChEBI: A benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary diseaseRoflumilast is a selective, orally active PDE4 inhibitor thatwas approvedin Germany in July 2010 as an add-on to bronchodilator treatment formaintenance therapy of severe chronic obstructive pulmonary disorder(COPDMore

Argipressine

CAS No: 113-79-1

Formula: C46H65N15O12S2

Categories: Active Pharmaceutical Ingredients > Urinary System Drugs

ChEBI: The predominant form of mammalian vasopressin (antidiuretic hormone). It is a nonapeptide containing an arginine at residue 8 and two disulfide-linked cysteines at residues of 1 and 6.Vasopressin tannate (PitressinTannate) is a water-insoluble tannate of vasopressin administeredintramuscularly (1.5–5.0 pressor units daily)for its prolonged duration of action by the slow release ofvasopressin. It is particularly useful for patients who havediabetes insipidus, but it should never be used iMore

Iron dextran

CAS No: 9004-66-4

Categories: Active Pharmaceutical Ingredients > Blood System Drugs

Light to dark brown powder. Colloidal suspension of an iron-dextran complex in water. pH 5.2-6.5.More

Sodium bromide

CAS No: 7647-15-6

Formula: BrNa

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Sodium bromide is an inorganic compound that appears as colorless cubic crystals or white granular powder, similar to sodium chloride. Its chemical formula is NaBr, its molecular weight is 102.89, it is odorless, and tastes salty and slightly bitter. Sodium bromide easily absorbs moisture in the air and clumps, but does not deliquesce. The aqueous solution of sodium bromide is neutral. It is slightly soluble in alcohol and can react with dilute sulfuric acid to produce hydrogen bromide. Under acidic conditions, sodium bromide can be oxidized to release bromine.More

Cromolyn Disodium Salt

CAS No: 15826-37-6

Formula: C23H17NaO11

Categories: Active Pharmaceutical Ingredients > Anti-sebum

Disodium cromoglycate, white to off-white powder, soluble in water, practically insoluble in ethanol. It is an organic sodium salt, the disodium salt of cromoglycic acid, with a molecular weight of 512.33, a melting point of 241-242°C, a boiling point of 752.3 °C, and a flash point of 263.9°C. Disodium cromoglycate is a compound that blocks the release of pro-inflammatory mediators, preventing the release of histamine, leukotrienes, and cytokines from mast cells. It does this by binding to calcium channels on the mast cell membrane, thereby preventing the influx of calcium ions necessary for the release of histamine and other mediators. It has also been found to reduce the expression of adhesion molecules and chemokines involved in inflammatory responses.More

PD 0332991 HCl

CAS No: 827022-32-2

Formula: C24H30ClN7O2

Categories: Active Pharmaceutical Ingredients > Inhibitor Drugs

Palbociclib hydrochloride is a highly selective CDK4/6 inhibitor with IC50s of 11 nM and 16 nM, respectively. More

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1,3,5-Trioxane, polymer with 1,3-dioxolane

CAS No: 24969-26-4

Formula: (C3H6O3.C3H6O2)x

Categories: Active Pharmaceutical Ingredients > Specialty Drugs

Paraformaldehyde is a white crystalline solid. Irritating odor. The term “trioxane” applies specifically to this trimer (CH2O)3 but paraformaldehyde is applied both to trioxane and other low polymers or oligomers of formaldehyde.More

Erythromycin

CAS No: 114-07-8

Formula: C37H67NO13

Categories: Active Pharmaceutical Ingredients > Antibiotics

Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.Target: AntibacterialErythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often prescribed for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including Mycoplasma and legioneMore

Aluminum chloride

CAS No: 7446-70-0

Formula: AlCl3

Categories: Active Pharmaceutical Ingredients > Astringent

Aluminum chloride is a noncombustible but highly reactive whitish-gray, yellow, or green powder or liquid. Strong, acidic, irritating odor like hydrochloric acid.The vapor consists of double molecules Al2Cl6 . Soluble in water.More

Potassium iodide

CAS No: 7681-11-0

Formula: IK

Categories: Active Pharmaceutical Ingredients > Antimicrobials

Colorless or white cubic crystals or granules; becomes yellowish when exposed to bright light due to photochemical decomposition liberating traces of free iodine; density 3.13 g/cm3; melts at 681°C; vaporizes at 1,330°C; highly soluble in water, ~140 g/100mL at 20°C; aqueous solution readily dissolves iodine; sparingly soluble in ethanol (about 2 g/100mL at 25°C) and acetone; slightly soluble in ether and ammonia. More

2,4-Hexadienoic acid, potassium salt (1:1)

CAS No: 590-00-1

Formula: C6H8O2.K

Categories: Active Pharmaceutical Ingredients > Cosmetic Preservative

It appears as white to pale yellow flaky crystals and crystalline powder or granular. It is odorless or slightly smelly. Long-term storage in the air is easy to absorb moisture and oxidative decomposition as well as coloring. Relative density (d2025): 1.363. The melting point temperature: 270 ° C (decomposition). It is easily soluble in water (67.6g/100ml, 20 ℃) 5% salt water (47.5g/100ml, room temperature), 25% sugar water (5lg/100ml, room temperature). It can be dissolved in propylene glycolMore

Imatinib mesylate

CAS No: 220127-57-1

Formula: C29H31N7O.CH4O3S

Categories: Active Pharmaceutical Ingredients > Antineoplastic Agents

Imatinib Mesylate is a tyrosine kinases inhibitor that inhibits c-Kit, Bcr-Abl, and PDGFR (IC50=100 nM) tyrosine kinases.More

Tylosin

CAS No: 1401-69-0

Formula: C46H77NO17

Categories: Active Pharmaceutical Ingredients > Feed Additive

Tylosin (Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms.More

Huperzine A

CAS No: 102518-79-6

Formula: C15H18N2O

Categories: Active Pharmaceutical Ingredients > Nervous System Drugs

Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). IC50 value:Target: AChEHuperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The huperzine A mechanism might beMore

Tolterodine

CAS No: 124937-51-5

Formula: C22H31NO

Categories: Active Pharmaceutical Ingredients > Urinary System Drugs

Pale Yellow GelTolterodine (Detrol), 2-[3-[bis(1-methylethyl)amino]-1-phenyl-propyl]-4-methyl-phenol, is an antimuscarinicagent that acts on M2 and M3 muscarinic subtypereceptors. By competitively blocking of the muscarinicreceptors results in a reduction of the smooth muscle tone,allowing for greater volume of urine to be stored in the bladder.This results in less urinary incontinence, urgency, andfrequency.More

Orotic acid

CAS No: 65-86-1

Formula: C5H4N2O4

Categories: Active Pharmaceutical Ingredients > Skin Conditioning

Orotic acid (OA) is an intermediate in pyrimidine metabolism.IC50 Value: Target: Nucleoside antimetabolite/analogin vitro: OA increases cell proliferation and decreases apoptosis in serum-starved SK-Hep1 hepatocellular carcinoma cells, which may ascribe to the inhibition of AMP-activated protein kinase (AMPK) phosphorylation and thus activation of mammalian target of rapamycin complex 1 (mTORC1) [1].in vivo: male Fischer 344 rats (130-150 g) to two-thirds PH in the absence or in the presMore

Active Pharmaceutical Ingredients Market

Market report will help you efficiently source API chemicals! ECHEMI can provide export and import data of API products you need to monitor and analyze the API market!
  • Phytosterol:

    40.0Yuan/kg -

Frequently Asked Questions

Are APIs safe to store and transport?

APIs must be handled according to regulatory and safety guidelines. Proper storage conditions, protective equipment, and transportation protocols are required to maintain stability and prevent contamination or hazards.

What industries use APIs?

APIs are widely used in pharmaceutical, veterinary, nutraceutical, and chemical research industries. They are essential for manufacturing medications, supplements, and experimental formulations.

How can I buy active pharmaceutical ingredients in bulk?

You can find certified API manufacturers and traders on ECHEMI. They provide detailed product information, CAS numbers, and safety data sheets (SDS) to ensure safe and reliable bulk purchases.

What are the top selling APIs on ECHEMI?

The top selling APIs on ECHEMI include Veterinary Raw Materials, Anesthetic Agents, Antiallergic Drugs, Feed Additives, Hormones and Endocrine Drugs, Digestive System Drugs, Vitamins and Minerals, Synthetic Anti-infective Drugs, Respiratory Drugs, and other chemical drugs.

What are active pharmaceutical ingredients?

Active Pharmaceutical Ingredients, also known as APIs, are the main active ingredients in a pharmaceutical drug to provide the intended therapeutic effect. APIs can be chemically synthesized or obtained from natural sources like plants and animals. After identifying the API, it is combined with other inactive ingredients to create a drug product that can be taken in different forms, such as tablets, capsules or injections.

What are the most common active pharmaceutical ingredients?

Here are some examples of common API chemicals.

1) Paracetamol (Acetaminophen) - a pain reliever and fever reducer

2) Ibuprofen - a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation

3) Aspirin - a medication used to reduce pain, fever, and inflammation and also used as a blood thinner

4) Amoxicillin - an antibiotic used to treat bacterial infections

5) Metformin - an oral medication for type 2 diabetes that lowers blood sugar levels

6) Omeprazole - a proton-pump inhibitor (PPI) used to reduce stomach acid production

7) Atorvastatin - a medication used to lower cholesterol levels in the blood

8) Sertraline - an antidepressant medication belonging to the class of selective serotonin reuptake inhibitors (SSRIs)

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