3-Hydroxy-N-(2-methylphenyl)-2-naphthalenecarboxamide

Using 2, 3-acid and o-toluidine as raw materials, firstly 2, 3-acid is made into sodium salt in chlorobenzene medium, and then condensed with o-toluidine in the presence of PCl3, and then neutralized, distilled, filtered and dried Get the finished product. Add 4000-4500L of chlorobenzene, 630kg of 2, 3-acid (100%), and 280kg of sodium carbonate into the salt-forming pot, and heat to 45℃. After the carbon dioxide escapes, continue to heat up to 134-135℃, and continue dehydration. When there is no water in the chlorobenzene to be distilled off, stop heating, and the volume of the material liquid is about 2800-3000L. The above-mentioned salt-forming reaction was hydraulically put into the condensation kettle, cooled to 90°C, 430kg (98%) o-toluidine was added, and cooling continued to 65-70°C, and the phosphorus trichloride-chlorobenzene mixture (230kg PCl3) was added within 2h. Use anhydrous chlorobenzene to make a 55%-60% mixture), and keep it at 119-120℃ for 2h after adding. Add 1000L of water and 330L of 30% sodium hydroxide solution into the distillation kettle, then press into the above condensate, stir for 15min, and determine the pH value should be 8-8.5. Then use direct steam distillation until the distillate is clear and chlorine-free benzene. Add hot water above 90°C until the material volume reaches about 5000L, filter, wash the filter cake with hot water above 90°C until the filtrate is clarified, drain the water, and dry to obtain about 885kg of finished product. During the condensation reaction, the solvent must be anhydrous (that is, the moisture content should be below 1%). Secondly, hydrogen chloride must be fully eliminated, otherwise it will seriously affect the product yield.

Mainly used as a primer for dyeing and printing cotton fabrics, and as an intermediate for fast pigments and organic pigments.

Molecular Weight:277.3
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:277.110278721
Monoisotopic Mass:277.110278721
Topological Polar Surface Area:49.3
Heavy Atom Count:21
Complexity:370
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes