The antibacterial property is similar to that of cefazolin, and it has good antibacterial effect on Staphylococcus aureus (including enzyme-producing strains), Streptococcus pyogenes, Pneumococcus, Escherichia coli, Proteus mirabilis, Haemophilus influenzae, etc.

A semi-synthetic antibiotic of the first generation of cephalosporins. Its antibacterial mechanism is to achieve the purpose of sterilization by interfering with the synthesis of cell walls. It generally has a strong antibacterial effect on Gram-positive bacteria, and also has a certain antibacterial effect on Gram-negative bacteria such as Escherichia coli and Shigella dysenteriae. Pseudomonas aeruginosa and Acinetobacter are resistant to this product.

A semi-synthetic antibiotic of the first generation of cephalosporins. Its antibacterial mechanism is to achieve the purpose of sterilization by interfering with the synthesis of cell walls. It generally has a strong antibacterial effect on Gram-positive bacteria, and also has a certain antibacterial effect on Gram-negative bacteria such as Escherichia coli and Shigella dysenteriae. Pseudomonas aeruginosa and Acinetobacter are resistant to this product.

This product is a semi-synthetic β-lactamase inhibitor, which has strong antibacterial activity against Neisseria gonorrhoeae, Neisseria meningitidis and Acinetobacter calcoaceticus, but has poor effects on other bacteria. When used in combination with penicillins and cephalosporins, it can reduce the MIC of Staphylococcus aureus, Haemophilus influenzae, Escherichia coli, Bacteroides fragilis, etc., which are resistant to the first two types of antibiotics due to enzyme production, to within the sensitive range.

It has a strong and irreversible competitive inhibitory effect on β-lactamases produced by Staphylococcus aureus and most Gram-negative bacteria. A concentration of 2 mg/L has a strong inhibitory effect on Richmond classification type II, III, IV and V β-lactamases, but has a poor effect on type I β-lactamases. It has a strong affinity for PBP1 of Bacillus paradoxus and PBP2 of Acinetobacter calcoaceticus.

The second generation of cephalosporin antibiotics, which are rapidly hydrolyzed into cefadroxil after entering the body, have strong antibacterial effects on most Gram-positive cocci, have good effects on diphtheria and Gram-positive anaerobic bacteria, have strong activity against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae and Haemophilus influenzae, and are sensitive to Salmonella typhi, Shigella, Neisseria gonorrhoeae and Neisseria meningitidis. The mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, inhibit the synthesis of bacterial septum and cell wall, make the bacteria longer in shape, and finally dissolve and die.