Butyl ether

130.22800

130.23

205-575-3

PBM2R52P5G

1150

8459

1149

DTXSID1022007

Colorless liquid

2909199090

9.23000

2.60320

N-butyl ether appears as a clear colorless liquid with an ethereal odor. Flash point below 141°F. Less dense than water and insoluble in water. Vapors heavier than air. Irritates the eyes, nose, throat, and respiratory tract.

0.7684 g/cm³ @ Temp: 20 °C

-95.2 °C

140.2 °C

25ºC

1.3978-1.3998

H2O: 0.03 g/100 mL (20 ºC)

Flammables area

4.8 mm Hg ( 20 °C)

4.48 (vs air)

Lower flammable limit: 1.5% by volume; Upper flammable limit: 7.6% by volume

vol% in air: 0.9.5

Mild, ethereal odor

2.88e-11 cm3/molecule*sec

0.01 atm-m3/mole|Henry's Law constant = 6.0X10-3 atm cu-m/mol at 25 °C

1 PPM= APPROX 5.33 MG/CU M @ 25 °C, 760 MM HG; 1 MG/L= APPROX 188 PPM @ 25 °C, 760 MM HG|LIQUID-WATER INTERFACIAL TENSION: (EST) 30 DYNES/CM= 0.030 N/M @ 20 °C|Azeotrope 67 wt% at 92.9 °C|Hydroxyl radical reaction rate constant = 2.88X10-11 cu cm/molecule-sec at 25 °C

Highly flammable. Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979 p.151-154, 164]. A mixture of liquid air and diethyl ether exploded spontaneously [MCA Case History 616 1960]. Insoluble in water.

Ethers

Highly Flammable

Ethers, such as BUTYL ETHER can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

Dibutyl ether|B*: Compounds that form peroxides on concentration (distillation/evaporation)|Moderate peroxides found in new commerically available containers|Bretherick's, Pubchem|Dasler,W.etal.,Ind.Eng.Chem.(Anal.Ed.),1946,18,52

382 °F (USCG, 1999)|382 °F (194 °C)|175 °C

-17,670 BTU/LB= -9,820 CAL/G= -411X10+5 JOULES/KG

Lower flammable limit: 1.5% by volume; Upper flammable limit: 7.6% by volume

As a result of flow, agitation, etc., electrostatic charges can be generated.

Latent heat of vaporization: 67.8 cal/g at 140.9 °C

III

3

UN 1149

2

R10; R36/37/38; R52/53

S61

EK5425000

Xi

Fireproof. Provision to contain effluent from fire extinguishing. Separated from incompatible materials. See Chemical Dangers. Cool. Keep in the dark. Store only if stabilized. Store in an area without drain or sewer access.

Stable. Flammable. May form peroxides in storage. Incompatible with strong oxidizing agents.

P210-P273-P280-P304 + P340 + P312-P337 + P313-P403 + P235

H226-H315-H319-H335-H412

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.|Incineration|The following wastewater treatment technologies have been investigated for butyl ether: Concentration process: Activated carbon.|Used ether containers, which are suspected of containing ether crystals or solids, are especially hazardous and may require bomb-squad assistance for their disposal. /Short alkyl-chain ethers/|This compound should be susceptible to removal from waste water by air stripping. /Bis(2-chloroethyl)ether/

Forms explosive mixture with air. May accumulate static electrical charges, and may cause ignition of its vapors. Incompatible with strong acids, oxidizers. Contact with air or light may form unstable and explosive peroxides, especially anhydrous form.|REACTS VIOLENTLY WITH NITROGEN TRICHLORIDE. ... CAN REACT WITH OXIDIZING MATERIALS.|alpha-Hydroperoxy ethers are obtained readily from the autoxidation of most ethers /including di-n-butyl ether/ containing alpha-hydrogens. From certain ethers ... the initially formed alpha-hydroperoxy ethers can ... with acid treatment, form dangerously sensitive and explosive polymeric peroxides.

Behavior in Fire: Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back. (USCG, 1999)|Flammable. Above 25 °C explosive vapour/air mixtures may be formed.|Flammable - 3rd degree, Reactive - 1st degree

|Warning|H226: Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P271, P273, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501|H226 (97.51%): Flammable liquid and vapor [Warning Flammable liquids]|Aggregated GHS information provided by 1323 companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Danger|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501

Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Goggles or face shield; rubber gloves. (USCG, 1999)|Wear protective gloves and clothing to prevent any reasonable probability of skin contact. Safety equipment suppliers/manufacturers can provide recommendations on the most protective glove/clothing material for your operation. All protective clothing (suits, gloves, footwear, headgear) should be clean, available each day, and put on before work. Contact lenses should not be worn when working with this chemical. Wear splash-proof chemical goggles and face shield unless full-piece respiratory protection is worn. Employees should wash immediately with soap when skin is wet or contaminated. Provide emergency showers and eyewash.|Wear full protective clothing and positive pressure self-contained breathing apparatus.

ONLY ELECTRICAL EQUIPMENT OF EXPLOSION-PROOF TYPE (GROUP C CLASSIFICATION) IS PERMITTED TO BE OPERATED IN ETHER AREAS. ETHER SHOULD NOT BE STORED NEAR POWERFUL OXIDIZERS OR IN AREAS OF HIGH FIRE HAZARD. /ETHERS/

MAY FORM EXPLOSIVE PEROXIDES, ESPECIALLY IN ANHYDROUS FORM.|lel: 1.5%; uel: 7.6%|Explosive limits , vol% in air: 0.9-8.5

Use dry chemical, foam, carbon dioxide or water spray. Water may be ineffective. Use water spray to keep fire-exposed containers cool.|Eliminate all ignition sources. Stop or control the leak, if this can be done without undue risk. Use appropriate foam to blanket release and suppress vapors. Absorb in noncombustible material for proper disposal.|If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.

Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or similar material and deposit in sealed containers. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.|Environmental considerations-land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents.|Environmental considerations-water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses.|Environmental considerations-air spill: Apply water spray or mist to knock down vapors.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|TO PREVENT EXPOSURE OF WORKERS TO HARMFUL CONCN OF SOLVENT VAPOR, MOST EFFECTIVE MEASURE IS ENCLOSURE OF PROCESS. LOCAL EXHAUST VENTILATION SHOULD BE INSTALLED ON ENCLOSURE ... /IF/ THIS IS NOT PRACTICABLE OPERATIONS MAY BE CONDUCTED UNDER HOOD FITTED WITH EXHAUST VENTILATION ... . /SOLVENTS INDUST/|... COMMON /ETHERS/ ... ARE EASILY IGNITED & HAVE LOW FLASH POINTS. IT IS NECESSARY TO CONTROL SMOKING, OPEN FLAMES OR HOT PLATES IN AREAS WHERE LOW MOL WT ETHERS ARE APT TO REACH 1% CONCN OR MORE IN AIR. /ETHERS/|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.|Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. Substances may be transported hot. /Dibutyl ethers/|/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Health: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. /Dibutyl ethers/|/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering. /Dibutyl ethers/|/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection. /Dibutyl ethers/|For more DOT Emergency Guidelines (Complete) data for DIBUTYL ETHER (8 total), please visit the HSDB record page.

Dibutyl ethers require a "Flammable Liquid" label. They fall into Hazard Class 3 and Packing Group III.|No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

At 200 ppm /is/ ... irritation to the eyes and nose.|... Seems to have a greater toxicity by inhalation than the lower ethers of the series. It is also more irritating to the skin.|Human systemic effects by inhalation: conjunctiva irritation and unspecified nasal effects. An experimental skin and human eye irritant.

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Cover the spilled material with foam. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Fireproof. Provision to contain effluent from fire extinguishing. Separated from incompatible materials. See Chemical Dangers. Cool. Keep in the dark. Store only if stabilized. Store in an area without drain or sewer access.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is mildly irritating to the eyes and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.

The substance defats the skin, which may cause dryness or cracking.

NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Above 25 °C use a closed system, ventilation and explosion-proof electrical equipment. Prevent build-up of electrostatic charges (e.g., by grounding).

Use ventilation, local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles.

| 1 - Materials that, under emergency conditions, can cause significant irritation.| 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions.| 1 - Materials that in themselves are normally stable but that can become unstable at elevated temperatures and pressures.

Dibutyl ether has been detected in 1 out of 63 samples of industrial effluents collected from a wide variety of industries across the U.S. at a concn of <10 ug/L (dates not reported)(1). Dibutyl ether was tentatively identified, but not quantified, in an advanced waste treatment concentrate from Lake Tahoe, CA, sampled in Oct 1974(2). Dibutyl ether was detected at concn of 5.6 and 0.2 ug/L in 2 of 7 sites sampled in Feb 1979 for standing water and impoundments which were discharged into Wilson Creek from a hazardous waste dump site called "Valley of the Drums" in Bullitt County, KY(3).

Dibutyl ether was qualitatively detected in the atmosphere of a chamber containing latex paint which suggests that the compound may be present in indoor air in buildings that have been painted with interior latex paint(1).

LD50 Rat oral 7.40 (6.41-8.53) mL/kg /from table/|LD50 Rabbit percutaneous 10.08 (4.41-23.04) mL/kg /from table/

Dibutyl ether's production and use as an extracting agent and solvent(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 51(SRC), determined from a structure estimation method(2), indicates that dibutyl ether is expected to have high mobility in soil(SRC). Volatilization of dibutyl ether from moist soil surfaces may be important(SRC) given a Henry's Law constant of 6.0X10-3 atm-cu m/mole(3). Volatilization of dibutyl ether from dry soil surfaces is expected(SRC) based upon an extrapolated vapor pressure of 6.0 mm Hg at 25 °C(4). Biodegradation of dibutyl ether in soil is expected to be a slow process(SRC), based upon its slow biodegradation in aqueous screening studies(5,6).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 51(SRC), determined from a structure estimation method(2), indicates that dibutyl ether is not expected to adsorb to suspended solids and sediment in water(SRC). Dibutyl ether is expected to volatilize from water surfaces(3) based on a Henry's Law constant of 6.0X10-3 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 3.5 hours and 4.6 days, respectively(SRC). According to a classification scheme(5), BCFs ranging from 30 to 114 measured in carp(6), suggest that bioconcentration in aquatic organisms is moderate to high(SRC). Biodegradation of dibutyl ether in water is expected to be a slow process(SRC), based upon its slow biodegradation in aqueous screening studies(6,7).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dibutyl ether, which has an extrapolated vapor pressure of 6.0 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dibutyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 13 hours(SRC) calculated from its rate constant of 2.88X10-11 cu cm/molecule-sec at 25 °C(3). Direct photolysis is not expected to be an important removal process since aliphatic ethers do not absorb light in the environmental spectrum(4).

The rate constant for the vapor-phase reaction of dibutyl ether with photochemically-produced hydroxyl radicals is 2.88X10-11 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 13 hours at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(SRC). Direct photolysis is not expected to be an important removal process since aliphatic ethers do not absorb light in the environmental spectrum(2). Dibutyl ether is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3).

72.44|BCFs of 47 to 83 and 30 to 114 were measured for carp exposed to 200 and 20 ug/L of dibutyl ether over the course of a 6 week incubation period(1). According to a classification scheme(2), these BCFs suggest bioconcentration in aquatic organisms is moderate to high, provided the compound is not metabolized by the organism(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for dibutyl ether can be estimated to be 51(SRC). According to a classification scheme(2), this estimated Koc value suggests that dibutyl ether is expected to have high mobility in soil(SRC).

The Henry's Law constant for dibutyl ether is 6.0X10-3 atm-cu m/mole(1). This Henry's Law constant indicates that dibutyl ether is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the estimated volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is approximately 3.5 hours(SRC). The estimated volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is approximately 4.6 days(SRC). Dibutyl ether's Henry's Law constant(1) indicates that volatilization from moist soil surfaces may occur(SRC). Volatilization of dibutyl ether from dry soil surfaces is expected(SRC) based upon an extrapolated vapor pressure of 6.0 mm Hg at 25 °C(3).

DRINKING WATER: Diethyl ether has been detected, but not quantified, in drinking water from unidentified sources(1).|GROUNDWATER: Dibutyl ether has been found in contaminated groundwater in The Netherlands at a max concn of 1 ug/L(1).|Dibutyl ether was detected at 1 ug/L in water from 3 sites on the River Rhine in The Netherlands sampled in 1979(1).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 6,292 workers (235 of these are female) are potentially exposed to dibutyl ether in the US(1). Occupational exposure to dibutyl ether may occur through inhalation and dermal contact with this compound at workplaces where dibutyl ether is produced or used(SRC).

0.56 Days

Inhalation causes irritation of nose and throat. Liquid irritates eyes and may irritate skin on prolonged contact. Ingestion causes irritation of mouth and stomach. (USCG, 1999)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Fresh air, rest. Refer for medical attention.

First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Ethers and related compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Provide a low-stimulus environment. Monitor for shock and treat if necessary ... Anticipate seizures and treat if necessary ... For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... Treat frostbite by rapid rewarming ... /Ethers and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Monitor cardiac rhythm and treat arrhythmias if necessary ... Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... Treat seizures with diazepam or lorazepam ... Use proparacaine hydrochloride to assist eye irrigation ... /Ethers and related compounds/

/SIGNS AND SYMPTOMS/ ... humans exposed to 100 ppm of dibutyl ether estimated it satisfactory for 8 hr exposures. At 200 ppm for 15 min the vapors produced a sensation of irritation to the eyes and nose, although at 300 ppm the odor was not objectionable to the majority of subjects.|/SIGNS AND SYMPTOMS/ Dibutyl ether, although not highly toxic orally, seems to have a greater toxicity by inhalation than the lower ethers of the series. It is also more irritating to the skin.

dibutyl ether

The substance can be absorbed into the body by inhalation of its vapour.

Cough. Sore throat.

Dry skin.

Redness. Pain.

Grade: Technical, spectrophotometric

All other basic inorganic chemical manufacturing|Butane, 1,1'-oxybis-: ACTIVE|Autooxidation produces di-n-butyl hydroperoxy ether

Dibutyl ether can be determined qualitatively and quantitatively by silica gel absorption, elution with ethanol, and gas chromatography of the eluate. It can also be determined by ... infrared analysis in a gas cell of long path length. /diethyl ether/|EPA Method 1625: Semivolatile Organic Compounds. An isotope dilution gas chromatography/mass spectrometry method for the determination of semivolatile organic compounds in municipal and industrial discharges, this method is designed to meet the survey requirements of Effluent Guidelines Division (EGD) and the National Pollution Discharge Elimination System (NPDES). /Semivolatile organic compounds/|NIOSH Method 1610: A gas chromatographic method for the analysis of ethyl ether, consists of a stainless steel column, 1.2 m x 6 mm OD, packed with Porapak Q (50/80 mesh), with hydrogen-air flame ionization detection, and nitrogen as the carrier gas at a flow rate of 30 ml/min, is a NIOSH approved method. A sample injection volume of 5 ul is suggested, the column temperature is 175 °C, the injection temperature is 195 °C, and the detection temperature is 250 °C. This method has a estimated detection limit of 0.01 mg/sample, and a relative standard deviation of 0.024 at 1.8 to 7.1 mg/sample over a working range of 100 to 2500 mg/sample. /Diethyl ether/|EPA Method 1624: An isotope dilution gas chromatography/ mass spectrometry method for the determination of volatile organic compounds in municipal and industrial discharges is described. This method is designed to meet the survey requirements of Effluent Guidelines Division (EGD) and the National Pollution Discharge Elimination System (NPDES). Under the prescribed conditions, unlabeled diethyl ether has a minimum level of 50 ug/l and a mean retention time of 820 sec. The labeled compound has a minimum level of 50 ug/L, a mean retention time of 804 sec, and a characteristic primary m/z of 74/84. /Diethyl ether/|For more Analytic Laboratory Methods (Complete) data for DIBUTYL ETHER (8 total), please visit the HSDB record page.

Ether in blood or urine is analyzed by direct injection of the specimen into a gas chromatograph equipped with a flame-ionization detector and a molecular sieve column. This method has a sensitivity of 10 mg/L, linearity of 10-200 mg/L, cv of 3-5% within-run, and a relative recovery of 96-100%. /Diethyl ether/

Fire Hazards -> Flammable - 3rd degree, Reactive - 1st degree